Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds
about
Genome-wide association study of bipolar disorder in Canadian and UK populations corroborates disease loci including SYNE1 and CSMD1LINC complexes mediate the positioning of cone photoreceptor nuclei in mouse retinaNuclear envelope: positioning nuclei and organizing synapsesMammalian microtubule P-body dynamics are mediated by nesprin-1.Novel nesprin-1 mutations associated with dilated cardiomyopathy cause nuclear envelope disruption and defects in myogenesis.Linker of nucleoskeleton and cytoskeleton complex proteins in cardiac structure, function, and disease.KASHing up with the nucleus: novel functional roles of KASH proteins at the cytoplasmic surface of the nucleus.Nesprin 1α2 is essential for mouse postnatal viability and nuclear positioning in skeletal muscleDisruption of both nesprin 1 and desmin results in nuclear anchorage defects and fibrosis in skeletal muscle.Cellular mechanosensing: getting to the nucleus of it all.First comparative transcriptomic analysis of wild adult male and female Lutzomyia longipalpis, vector of visceral leishmaniasisNuclear forces and cell mechanosensing.Large-scale modelling of the divergent spectrin repeats in nesprins: giant modular proteinsAccessorizing and anchoring the LINC complex for multifunctionality.Mutations in LMNA modulate the lamin A--Nesprin-2 interaction and cause LINC complex alterationsNuclear envelope in nuclear positioning and cell migrationNesprins: tissue-specific expression of epsilon and other short isoforms.Making the LINC: SUN and KASH protein interactions.A variant of Nesprin1 giant devoid of KASH domain underlies the molecular etiology of autosomal recessive cerebellar ataxia type INuclear membrane diversity: underlying tissue-specific pathologies in disease?Hereditary protein S deficiency leads to ischemic strokeSun1 deficiency leads to cerebellar ataxia in miceNesprin-2-dependent ERK1/2 compartmentalisation regulates the DNA damage response in vascular smooth muscle cell ageingSpecific localization of nesprin-1-α2, the short isoform of nesprin-1 with a KASH domain, in developing, fetal and regenerating muscle, using a new monoclonal antibody.Nuclear mechanics in cancerCell Mechanosensitivity is Enabled by the LINC Nuclear Complex.Nonsteroidal anti-inflammatory drug sulindac sulfide suppresses structural protein Nesprin-2 expression in colorectal cancer cellsMutations in Hedgehog pathway genes in fetal rhabdomyomasDevelopmental regulation of linkers of the nucleoskeleton to the cytoskeleton during mouse postnatal retinogenesis.Opposing roles for distinct LINC complexes in regulation of the small GTPase RhoA.Nesprins: from the nuclear envelope and beyond.Composite biopolymer scaffolds shape muscle nucleus: Insights and perspectives from Drosophila.Multiple Isoforms of Nesprin1 Are Integral Components of Ciliary Rootlets.Whole Exome Sequencing Identifies Truncating Variants in Nuclear Envelope Genes in Patients With Cardiovascular Disease.N-terminal nesprin-2 variants regulate β-catenin signallingMechanotransduction and nuclear function.Nesprin-1 role in DNA damage responseIdentification of novel nesprin-1 binding partners and cytoplasmic matrin-3 in processing bodiesNesprin-1α-Dependent Microtubule Nucleation from the Nuclear Envelope via Akap450 Is Necessary for Nuclear Positioning in Muscle Cells.Nesprin-2 Interacts with Condensin Component SMC2.
P2860
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P2860
Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds
description
2012 nî lūn-bûn
@nan
2012 թուականին հրատարակուած գիտական յօդուած
@hyw
2012 թվականին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Multiple novel nesprin-1 and n ...... ecific intracellular scaffolds
@ast
Multiple novel nesprin-1 and n ...... ecific intracellular scaffolds
@en
Multiple novel nesprin-1 and n ...... ecific intracellular scaffolds
@en-gb
Multiple novel nesprin-1 and n ...... ecific intracellular scaffolds
@nl
type
label
Multiple novel nesprin-1 and n ...... ecific intracellular scaffolds
@ast
Multiple novel nesprin-1 and n ...... ecific intracellular scaffolds
@en
Multiple novel nesprin-1 and n ...... ecific intracellular scaffolds
@en-gb
Multiple novel nesprin-1 and n ...... ecific intracellular scaffolds
@nl
altLabel
Multiple Novel Nesprin-1 and N ...... ecific Intracellular Scaffolds
@en
prefLabel
Multiple novel nesprin-1 and n ...... ecific intracellular scaffolds
@ast
Multiple novel nesprin-1 and n ...... ecific intracellular scaffolds
@en
Multiple novel nesprin-1 and n ...... ecific intracellular scaffolds
@en-gb
Multiple novel nesprin-1 and n ...... ecific intracellular scaffolds
@nl
P2093
P2860
P3181
P1433
P1476
Multiple novel nesprin-1 and n ...... ecific intracellular scaffolds
@en
P2093
Dipen Rajgor
Flavia Autore
Jason A Mellad
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0040098
P407
P577
2012-01-01T00:00:00Z