Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness
about
Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffoldsLULL1 retargets TorsinA to the nuclear envelope revealing an activity that is impaired by the DYT1 dystonia mutationLINC complex alterations in DMD and EDMD/CMT fibroblastsMammalian SUN protein interaction networks at the inner nuclear membrane and their role in laminopathy disease processesLINC complexes form by binding of three KASH peptides to domain interfaces of trimeric SUN proteinsNesprin-3 regulates endothelial cell morphology, perinuclear cytoskeletal architecture, and flow-induced polarizationA lamin in lower eukaryotes?Nuclear motility in glioma cells reveals a cell-line dependent role of various cytoskeletal componentsLINC complexes mediate the positioning of cone photoreceptor nuclei in mouse retinaMammalian sperm head formation involves different polarization of two novel LINC complexesStructural insights into SUN-KASH complexes across the nuclear envelopeStructure of Sad1-UNC84 Homology (SUN) Domain Defines Features of Molecular Bridge in Nuclear EnvelopeNuclear envelope: positioning nuclei and organizing synapsesMammalian microtubule P-body dynamics are mediated by nesprin-1.Cell Mechanosensitivity to Extremely Low-Magnitude Signals Is Enabled by a LINCed NucleusA novel mouse synaptonemal complex protein is essential for loading of central element proteins, recombination, and fertilityActin cap associated focal adhesions and their distinct role in cellular mechanosensingAltered nuclear dynamics in MDX myofibers.LINC'ing form and function at the nuclear envelope.The interaction between nesprins and sun proteins at the nuclear envelope is critical for force transmission between the nucleus and cytoskeleton.Integration of basal topographic cues and apical shear stress in vascular endothelial cellsNuclear pore complex evolution: a trypanosome Mlp analogue functions in chromosomal segregation but lacks transcriptional barrier activityLamin B2 prevents chromosome instability by ensuring proper mitotic chromosome segregation.Tight coupling between nucleus and cell migration through the perinuclear actin capNucleus-dependent sarcomere assembly is mediated by the LINC complex.Novel nesprin-1 mutations associated with dilated cardiomyopathy cause nuclear envelope disruption and defects in myogenesis.Linker of nucleoskeleton and cytoskeleton complex proteins in cardiac structure, function, and disease.Nesprin 1 is critical for nuclear positioning and anchorageThe Soft- and Hard-Heartedness of Cardiac Fibroblasts: Mechanotransduction Signaling Pathways in Fibrosis of the Heart.Interactions between nuclei and the cytoskeleton are mediated by SUN-KASH nuclear-envelope bridges.Lamin-binding ProteinsStructure and expression of the maize (Zea mays L.) SUN-domain protein gene family: evidence for the existence of two divergent classes of SUN proteins in plantsKASHing up with the nucleus: novel functional roles of KASH proteins at the cytoplasmic surface of the nucleus.Actomyosin tension exerted on the nucleus through nesprin-1 connections influences endothelial cell adhesion, migration, and cyclic strain-induced reorientation.The Drosophila SUN protein Spag4 cooperates with the coiled-coil protein Yuri Gagarin to maintain association of the basal body and spermatid nucleus.Nuclear lamins.Nesprin-2 interacts with {alpha}-catenin and regulates Wnt signaling at the nuclear envelope.The differential formation of the LINC-mediated perinuclear actin cap in pluripotent and somatic cells.Structural insight into the central element assembly of the synaptonemal complexLINC complexes in health and disease.
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P2860
Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness
description
2008 nî lūn-bûn
@nan
2008 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Structural requirements for th ...... cellular mechanical stiffness
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Structural requirements for th ...... cellular mechanical stiffness
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Structural requirements for th ...... cellular mechanical stiffness
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Structural requirements for th ...... cellular mechanical stiffness
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Structural requirements for th ...... cellular mechanical stiffness
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Structural requirements for th ...... cellular mechanical stiffness
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Structural requirements for th ...... cellular mechanical stiffness
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Structural requirements for th ...... cellular mechanical stiffness
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Structural requirements for th ...... cellular mechanical stiffness
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Structural requirements for th ...... cellular mechanical stiffness
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Structural requirements for th ...... cellular mechanical stiffness
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Structural requirements for th ...... cellular mechanical stiffness
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Structural requirements for th ...... cellular mechanical stiffness
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Denis Wirtz
Didier Hodzic
P J Stewart-Hutchinson
P2860
P304
P3181
P356
10.1016/J.YEXCR.2008.02.022
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2008-03-12T00:00:00Z