Functional characterization of CLPTM1L as a lung cancer risk candidate gene in the 5p15.33 locus
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Imputation and subset based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33Pancreatic Cancer GeneticsEpidemiology and Inherited Predisposition for Sporadic Pancreatic AdenocarcinomaGenetic variations in the TERT and CLPTM1L gene region and gastrointestinal stromal tumors riskThe identification of two regulatory ESCC susceptibility genetic variants in the TERT-CLPTM1L lociFunctional evaluation of TERT-CLPTM1L genetic variants associated with susceptibility of papillary thyroid carcinomaCLPTM1L is overexpressed in lung cancer and associated with apoptosisThree new pancreatic cancer susceptibility signals identified on chromosomes 1q32.1, 5p15.33 and 8q24.21Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148CLPTM1L promotes growth and enhances aneuploidy in pancreatic cancer cellsTERT-CLPTM1L Rs401681 C>T polymorphism was associated with a decreased risk of esophageal cancer in a Chinese populationCRR9/CLPTM1L regulates cell survival signaling and is required for Ras transformation and lung tumorigenesis.Association of GWAS-identified lung cancer susceptibility loci with survival length in patients with small-cell lung cancer treated with platinum-based chemotherapyGenetic variations rs11892031 and rs401681 are associated with bladder cancer risk in a Chinese populationReplication study in Chinese population and meta-analysis supports association of the 5p15.33 locus with lung cancer.Bridging the clinical gaps: genetic, epigenetic and transcriptomic biomarkers for the early detection of lung cancer in the post-National Lung Screening Trial eraThe SNP rs402710 in 5p15.33 is associated with lung cancer risk: a replication study in Chinese population and a meta-analysisGenetic variant rs401681 at 5p15.33 modifies susceptibility to lung cancer but not esophageal squamous cell carcinomaCLPTM1L polymorphism and lung cancer riskCLPTM1L genetic polymorphisms and interaction with smoking and alcohol drinking in lung cancer risk: a case-control study in the Han population from northwest China.Regulation of the Human Telomerase Gene TERT by Telomere Position Effect-Over Long Distances (TPE-OLD): Implications for Aging and Cancer.Lung Cancer Risk Prediction Using Common SNPs Located in GWAS-Identified Susceptibility RegionsCommon variations in TERT-CLPTM1L locus are reproducibly associated with the risk of nasopharyngeal carcinoma in Chinese populationsGenetic polymorphisms of TERT and CLPTM1L and risk of lung cancer--a case-control study in a Chinese population.Novel Anti-CRR9/CLPTM1L Antibodies with Antitumorigenic Activity Inhibit Cell Surface Accumulation, PI3K Interaction, and Survival Signaling.Urinary bladder cancer susceptibility markers. What do we know about functional mechanisms?EGFR and KRAS mutations, and ALK fusions: current developments and personalized therapies for patients with advanced non-small-cell lung cancer.Prognostic significance of CLPTM1L expression and its effects on migration and invasion of human lung cancer cells.Inhibition of IGF1R signaling abrogates resistance to afatinib (BIBW2992) in EGFR T790M mutant lung cancer cells.Friend or foe? Telomerase as a pharmacological target in cancer and cardiovascular disease.Upregulation of miR-494 Inhibits Cell Growth and Invasion and Induces Cell Apoptosis by Targeting Cleft Lip and Palate Transmembrane 1-Like in Esophageal Squamous Cell Carcinoma.The associations of TERT-CLPTM1L variants and TERT mRNA expression with the prognosis of early stage non-small cell lung cancer.The Potential Role of Krüppel-Like Zinc-Finger Protein Glis3 in Genetic Diseases and Cancers.Immortalization of epithelial cells in oral carcinogenesis as revealed by genome-wide array comparative genomic hybridization: A meta-analysis.A GWAS in uveal melanoma identifies risk polymorphisms in the CLPTM1L locus.Reconstruction of an integrated genome-scale co-expression network reveals key modules involved in lung adenocarcinoma.Genetic variations in TERT-CLPTM1L locus are associated with risk of lung cancer in Chinese population.Inherited pancreatic cancer.An extended genome-wide association study identifies novel susceptibility loci for nasopharyngeal carcinoma.Correlation of CLPTM1L polymorphisms with lung cancer susceptibility and response to cisplatin-based chemotherapy in a Chinese Han population.
P2860
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P2860
Functional characterization of CLPTM1L as a lung cancer risk candidate gene in the 5p15.33 locus
description
2012 nî lūn-bûn
@nan
2012 թուականին հրատարակուած գիտական յօդուած
@hyw
2012 թվականին հրատարակված գիտական հոդված
@hy
2012年の論文
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2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
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name
Functional characterization of ...... date gene in the 5p15.33 locus
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Functional characterization of ...... date gene in the 5p15.33 locus
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Functional characterization of ...... date gene in the 5p15.33 locus
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Functional characterization of ...... date gene in the 5p15.33 locus
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type
label
Functional characterization of ...... date gene in the 5p15.33 locus
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Functional characterization of ...... date gene in the 5p15.33 locus
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Functional characterization of ...... date gene in the 5p15.33 locus
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Functional characterization of ...... date gene in the 5p15.33 locus
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Functional Characterization of ...... date Gene in the 5p15.33 Locus
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prefLabel
Functional characterization of ...... date gene in the 5p15.33 locus
@ast
Functional characterization of ...... date gene in the 5p15.33 locus
@en
Functional characterization of ...... date gene in the 5p15.33 locus
@en-gb
Functional characterization of ...... date gene in the 5p15.33 locus
@nl
P2093
P2860
P3181
P1433
P1476
Functional characterization of ...... date gene in the 5p15.33 locus
@en
P2093
John Minna
Lauren A Byers
Luc Girard
Michael A James
Weidong Wen
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0036116
P407
P577
2012-01-01T00:00:00Z