Membrane binding by tBid initiates an ordered series of events culminating in membrane permeabilization by Bax
about
Functional characterization of CLPTM1L as a lung cancer risk candidate gene in the 5p15.33 locusUse of human cancer cell lines mitochondria to explore the mechanisms of BH3 peptides and ABT-737-induced mitochondrial membrane permeabilizationActive Bax and Bak are functional holinstBid undergoes multiple conformational changes at the membrane required for Bax activationBcl-x(L) retrotranslocates Bax from the mitochondria into the cytosolMembrane remodeling induced by the dynamin-related protein Drp1 stimulates Bax oligomerizationHeterodimerization of BAK and MCL-1 activated by detergent micellesBcl-xL phosphorylation at Ser49 by polo kinase 3 during cell cycle progression and checkpointsBax activates endophilin B1 oligomerization and lipid membrane vesiculationMutation to Bax beyond the BH3 domain disrupts interactions with pro-survival proteins and promotes apoptosisMaking heads or tails of phospholipids in mitochondriaProgrammed Cell Death Initiation and Execution in Budding YeastAPOL1 Kidney Disease Risk Variants: An Evolving LandscapePhotoreceptor cell death and rescue in retinal detachment and degenerationsA new view of the lethal apoptotic poreBAX unleashed: the biochemical transformation of an inactive cytosolic monomer into a toxic mitochondrial poreThe BCL2 Family: Key Mediators of the Apoptotic Response to Targeted Anticancer TherapeuticsApoptotic agentsIntegration and oligomerization of Bax protein in lipid bilayers characterized by single molecule fluorescence studyHigh throughput ratio imaging to profile caspase activity: potential application in multiparameter high content apoptosis analysis and drug screeningEvidence that inhibition of BAX activation by BCL-2 involves its tight and preferential interaction with the BH3 domain of BAXInhibition of Apoptosis and NF-κB Activation by Vaccinia Protein N1 Occur via Distinct Binding Surfaces and Make Different Contributions to VirulenceBID-induced structural changes in BAK promote apoptosisStructural Insights of tBid, the Caspase-8-activated Bid, and Its BH3 DomainBh3 induced conformational changes in Bcl-Xl revealed by crystal structure and comparative analysisA yeast BH3-only protein mediates the mitochondrial pathway of apoptosis.APOL1 toxin, innate immunity, and kidney injuryBuilding blocks of the apoptotic pore: how Bax and Bak are activated and oligomerize during apoptosisMinimalist Model Systems Reveal Similarities and Differences between Membrane Interaction Modes of MCL1 and BAKPermeabilization of the mitochondrial outer membrane by Bax/truncated Bid (tBid) proteins as sensitized by cardiolipin hydroperoxide translocation: mechanistic implications for the intrinsic pathway of oxidative apoptosisEfficient elimination of cancer cells by deoxyglucose-ABT-263/737 combination therapyCharge profile analysis reveals that activation of pro-apoptotic regulators Bax and Bak relies on charge transfer mediated allosteric regulationBax activation initiates the assembly of a multimeric catalyst that facilitates Bax pore formation in mitochondrial outer membranesApaf-1 inhibitors protect from unwanted cell death in in vivo models of kidney ischemia and chemotherapy induced ototoxicityBOK Is a Non-canonical BCL-2 Family Effector of Apoptosis Regulated by ER-Associated DegradationMTCH2/MIMP is a major facilitator of tBID recruitment to mitochondriaActive fragments from pro- and antiapoptotic BCL-2 proteins have distinct membrane behavior reflecting their functional divergenceIdentification of Bax-interacting proteins in oligodendrocyte progenitors during glutamate excitotoxicity and perinatal hypoxia-ischemiaThe functional differences between pro-survival and pro-apoptotic B cell lymphoma 2 (Bcl-2) proteins depend on structural differences in their Bcl-2 homology 3 (BH3) domains.Synthetic Antibodies Inhibit Bcl-2-associated X Protein (BAX) through Blockade of the N-terminal Activation Site.
P2860
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P2860
Membrane binding by tBid initiates an ordered series of events culminating in membrane permeabilization by Bax
description
2008 nî lūn-bûn
@nan
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Membrane binding by tBid initi ...... mbrane permeabilization by Bax
@ast
Membrane binding by tBid initi ...... mbrane permeabilization by Bax
@en
Membrane binding by tBid initi ...... mbrane permeabilization by Bax
@en-gb
Membrane binding by tBid initi ...... mbrane permeabilization by Bax
@nl
type
label
Membrane binding by tBid initi ...... mbrane permeabilization by Bax
@ast
Membrane binding by tBid initi ...... mbrane permeabilization by Bax
@en
Membrane binding by tBid initi ...... mbrane permeabilization by Bax
@en-gb
Membrane binding by tBid initi ...... mbrane permeabilization by Bax
@nl
prefLabel
Membrane binding by tBid initi ...... mbrane permeabilization by Bax
@ast
Membrane binding by tBid initi ...... mbrane permeabilization by Bax
@en
Membrane binding by tBid initi ...... mbrane permeabilization by Bax
@en-gb
Membrane binding by tBid initi ...... mbrane permeabilization by Bax
@nl
P2093
P50
P921
P3181
P1433
P1476
Membrane binding by tBid initi ...... mbrane permeabilization by Bax
@en
P2093
Aisha Shamas-Din
Brian Leber
Lieven P Billen
Scott Bindner
P304
P3181
P356
10.1016/J.CELL.2008.11.010
P407
P577
2008-12-01T00:00:00Z