Targeted inhibition of miRNA maturation with morpholinos reveals a role for miR-375 in pancreatic islet development
about
Rapid generation of microRNA sponges for microRNA inhibitionPolymerase-endonuclease amplification reaction (PEAR) for large-scale enzymatic production of antisense oligonucleotidesThe promoter of the pri-miR-375 gene directs expression selectively to the endocrine pancreasMiR-10 represses HoxB1a and HoxB3a in zebrafishInhibition of microRNA function by antimiR oligonucleotidesGenomic organization of zebrafish microRNAsMost Caenorhabditis elegans microRNAs are individually not essential for development or viabilityThe microRNA-30 family is required for vertebrate hepatobiliary developmentmiR-375 targets 3'-phosphoinositide-dependent protein kinase-1 and regulates glucose-induced biological responses in pancreatic beta-cellsmiR-122 targeting with LNA/2'-O-methyl oligonucleotide mixmers, peptide nucleic acids (PNA), and PNA-peptide conjugatesmiR-451 regulates zebrafish erythroid maturation in vivo via its target gata2Zebrafish miR-1 and miR-133 shape muscle gene expression and regulate sarcomeric actin organizationmiR-375 maintains normal pancreatic alpha- and beta-cell massRegenerative Therapy of Type 1 Diabetes Mellitus: From Pancreatic Islet Transplantation to Mesenchymal Stem CellsEpigenetics: the missing link to understanding β-cell dysfunction in the pathogenesis of type 2 diabetesMicroRNAs as pharmacological targets in diabetesStructure based approaches for targeting non-coding RNAs with small moleculesRole of microRNAs in islet beta-cell compensation and failure during diabetesThe emerging use of zebrafish to model metabolic diseaseNoncoding RNAs: key molecules in understanding and treating painHuman cellular microRNA hsa-miR-29a interferes with viral nef protein expression and HIV-1 replicationAlterations of Epigenetic Regulators in Pancreatic Cancer and Their Clinical ImplicationsTissue and serum microRNAs in the Kras(G12D) transgenic animal model and in patients with pancreatic cancerMembers of the miRNA-200 family regulate olfactory neurogenesisMicroRNAs are essential for development and function of inner ear hair cells in vertebratesPigmy MicroRNA: surveillance cops in Therapies kingdomSilencing disease genes in the laboratory and the clinicDevelopmental suppression of schizophrenia-associated miR-137 alters sensorimotor function in zebrafish.miR-19b Regulates Ventricular Action Potential Duration in Zebrafish.Podocyte-selective deletion of dicer induces proteinuria and glomerulosclerosis.The Story of SPATA2 (Spermatogenesis-Associated Protein 2): From Sertoli Cells to Pancreatic Beta-CellsmicroRNA-210-3p depletion by CRISPR/Cas9 promoted tumorigenesis through revival of TWIST1 in renal cell carcinoma.MicroRNAs in metabolism and metabolic disordersSynthetic strategies for studying embryonic development.MicroRNA signature of the human developing pancreas.Identification of restricted subsets of mature microRNA abnormally expressed in inactive colonic mucosa of patients with inflammatory bowel disease.MicroRNA-183 family members regulate sensorineural fates in the inner ear.MicroRNA-17~92 is required for nephrogenesis and renal functionRegulation of retinal inflammation by rhythmic expression of MiR-146a in diabetic retina.Quantitative differential expression analysis reveals miR-7 as major islet microRNA.
P2860
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P2860
Targeted inhibition of miRNA maturation with morpholinos reveals a role for miR-375 in pancreatic islet development
description
2007 nî lūn-bûn
@nan
2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Targeted inhibition of miRNA m ...... n pancreatic islet development
@ast
Targeted inhibition of miRNA m ...... n pancreatic islet development
@en
Targeted inhibition of miRNA m ...... n pancreatic islet development
@en-gb
Targeted inhibition of miRNA m ...... n pancreatic islet development
@nl
type
label
Targeted inhibition of miRNA m ...... n pancreatic islet development
@ast
Targeted inhibition of miRNA m ...... n pancreatic islet development
@en
Targeted inhibition of miRNA m ...... n pancreatic islet development
@en-gb
Targeted inhibition of miRNA m ...... n pancreatic islet development
@nl
altLabel
Targeted Inhibition of miRNA M ...... n Pancreatic Islet Development
@en
prefLabel
Targeted inhibition of miRNA m ...... n pancreatic islet development
@ast
Targeted inhibition of miRNA m ...... n pancreatic islet development
@en
Targeted inhibition of miRNA m ...... n pancreatic islet development
@en-gb
Targeted inhibition of miRNA m ...... n pancreatic islet development
@nl
P2093
P2860
P3181
P1433
P1476
Targeted inhibition of miRNA m ...... n pancreatic islet development
@en
P2093
Jon D Moulton
René F Ketting
Ronald H A Plasterk
Wigard P Kloosterman
P2860
P3181
P356
10.1371/JOURNAL.PBIO.0050203
P407
P577
2007-08-01T00:00:00Z