P688
A novel protein with RNA-binding motifs interacts with ataxin-2Nuclear localization or inclusion body formation of ataxin-2 are not necessary for SCA2 pathogenesis in mouse or humanAtaxin-2 and its Drosophila homolog, ATX2, physically assemble with polyribosomesAtaxin-2 interacts with the DEAD/H-box RNA helicase DDX6 and interferes with P-bodies and stress granulesExpansion of the polyQ repeat in ataxin-2 alters its Golgi localization, disrupts the Golgi complex and causes cell deathAtaxin-2 associates with the endocytosis complex and affects EGF receptor traffickingAn integrative approach to gain insights into the cellular function of human ataxin-2
P921
Q22254111-C7F121ED-D192-43C4-A17D-733849021E2BQ24290184-2E37B593-5B4B-4675-82B1-332F8CCE9BDDQ24296835-5D270122-32E6-42F4-BFF9-B93CF4039D12Q24301077-F5385F0F-BC1F-4518-98AE-70C7FDEEB874Q24305414-5D7DC25C-105F-4764-B434-C973D721A7CCQ24310002-2338DD49-B956-4536-8F45-7C745093C482Q24338666-05232D40-3839-4324-8093-90AE73691386
P921
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
menselijk eiwit
@nl
protein
@id
proteinë
@sq
protèin
@ace
protéine humaine
@fr
بروتين بشري
@ar
name
ATXN2
@uk
Ataxin 2
@en
Ataxin 2
@nl
Ataxin-2
@de
type
label
ATXN2
@uk
Ataxin 2
@en
Ataxin 2
@nl
Ataxin-2
@de
altLabel
ATXN2
@en
ataxin-2
@en
spinocerebellar ataxia type 2 protein
@en
trinucleotide repeat-containing gene 13 protein
@en
prefLabel
ATXN2
@uk
Ataxin 2
@en
Ataxin 2
@nl
Ataxin-2
@de
P361
P527
P637
P680
P681
P682
P705
P352
P486
P638
P31
P352
P486
D000067698
P637
NP_001297050
NP_001297052
NP_001359503
P681
P682
P702
P703
P705
ENSP00000373805
ENSP00000373806
ENSP00000439338
ENSP00000445583
ENSP00000446512
ENSP00000446576
ENSP00000447225
ENSP00000447741
ENSP00000448640
ENSP00000474442