Ataxin-2 and its Drosophila homolog, ATX2, physically assemble with polyribosomes
about
Structural basis of binding of P-body-associated proteins GW182 and ataxin-2 by the Mlle domain of poly(A)-binding proteinAtaxin-2 interacts with the DEAD/H-box RNA helicase DDX6 and interferes with P-bodies and stress granulesAtaxin-2-like is a regulator of stress granules and processing bodiesCell biology of spinocerebellar ataxiaATX-2, the C. elegans Ortholog of Human Ataxin-2, Regulates Centrosome Size and Microtubule DynamicsAtaxin-2 regulates RGS8 translation in a new BAC-SCA2 transgenic mouse modeldAtaxin-2 mediates expanded Ataxin-1-induced neurodegeneration in a Drosophila model of SCA1Motor Dysfunctions and Neuropathology in Mouse Models of Spinocerebellar Ataxia Type 2: A Comprehensive ReviewDrosophila as an In Vivo Model for Human Neurodegenerative Disease12q24 locus association with type 1 diabetes: SH2B3 or ATXN2?Ataxin-2 modulates the levels of Grb2 and SRC but not ras signaling.Therapeutic prospects for spinocerebellar ataxia type 2 and 3.The RNA-binding protein ATX-2 regulates cytokinesis through PAR-5 and ZEN-4Polyglutamine genes interact to modulate the severity and progression of neurodegeneration in Drosophila.Dissociated fear and spatial learning in mice with deficiency of ataxin-2Genetic variance in the spinocerebellar ataxia type 2 (ATXN2) gene in children with severe early onset obesity.Conserved genes act as modifiers of invertebrate SMN loss of function defectsAtaxin-2: From RNA Control to Human Health and DiseasePoly(A)-binding proteins are required for diverse biological processes in metazoans.Neurodegenerative models in Drosophila: polyglutamine disorders, Parkinson disease, and amyotrophic lateral sclerosis.Roles of ataxin-2 in pathological cascades mediated by TAR DNA-binding protein 43 (TDP-43) and Fused in Sarcoma (FUS)ETS1 regulates the expression of ATXN2.ATXN2 and its neighbouring gene SH2B3 are associated with increased ALS risk in the Turkish populationATXN2-CAG42 sequesters PABPC1 into insolubility and induces FBXW8 in cerebellum of old ataxic knock-in mice.Large-scale screen for modifiers of ataxin-3-derived polyglutamine-induced toxicity in Drosophila.The novel gene twenty-four defines a critical translational step in the Drosophila clock.Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models.Both ubiquitin ligases FBXW8 and PARK2 are sequestrated into insolubility by ATXN2 PolyQ expansions, but only FBXW8 expression is dysregulated.The Ataxin-2 protein is required for microRNA function and synapse-specific long-term olfactory habituation.Unexpanded and intermediate CAG polymorphisms at the SCA2 locus (ATXN2) in the Cuban population: evidence about the origin of expanded SCA2 alleles.RNA-binding protein misregulation in microsatellite expansion disordersP-body assembly requires DDX6 repression complexes rather than decay or Ataxin2/2L complexes.Changes in Purkinje cell firing and gene expression precede behavioral pathology in a mouse model of SCA2Epigenetics in nucleotide repeat expansion disorders.Degenerative ataxias, from genes to therapies: The 2015 Cotzias Lecture.Decoding Parkinson's Disease Pathogenesis: The Role of Deregulated mRNA Translation.RNA-binding proteins in neurodegenerative disease: TDP-43 and beyond.Emerging pathogenic pathways in the spinocerebellar ataxias.Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 2.Drosophila ataxin-2 gene encodes two differentially expressed isoforms and its function in larval fat body is crucial for development of peripheral tissues
P2860
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P2860
Ataxin-2 and its Drosophila homolog, ATX2, physically assemble with polyribosomes
description
2006 nî lūn-bûn
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2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
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2006 թվականի օգոստոսին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
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2006年論文
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2006年论文
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name
Ataxin-2 and its Drosophila homolog, ATX2, physically assemble with polyribosomes
@ast
Ataxin-2 and its Drosophila homolog, ATX2, physically assemble with polyribosomes
@en
Ataxin-2 and its Drosophila homolog, ATX2, physically assemble with polyribosomes
@en-gb
Ataxin-2 and its Drosophila homolog, ATX2, physically assemble with polyribosomes
@nl
type
label
Ataxin-2 and its Drosophila homolog, ATX2, physically assemble with polyribosomes
@ast
Ataxin-2 and its Drosophila homolog, ATX2, physically assemble with polyribosomes
@en
Ataxin-2 and its Drosophila homolog, ATX2, physically assemble with polyribosomes
@en-gb
Ataxin-2 and its Drosophila homolog, ATX2, physically assemble with polyribosomes
@nl
prefLabel
Ataxin-2 and its Drosophila homolog, ATX2, physically assemble with polyribosomes
@ast
Ataxin-2 and its Drosophila homolog, ATX2, physically assemble with polyribosomes
@en
Ataxin-2 and its Drosophila homolog, ATX2, physically assemble with polyribosomes
@en-gb
Ataxin-2 and its Drosophila homolog, ATX2, physically assemble with polyribosomes
@nl
P2860
P3181
P356
P1476
Ataxin-2 and its Drosophila homolog, ATX2, physically assemble with polyribosomes
@en
P2093
Leo J Pallanck
Terrence F Satterfield
P2860
P304
P3181
P356
10.1093/HMG/DDL173
P407
P577
2006-08-15T00:00:00Z