about
P129
Mature HIV virionVirion with CD4 bound to gp120Virion with exposed coreceptor binding sitesVirion with CD4:gp120 bound to CCR5/CXCR4Virion with gp41 exposedVirion with fusogenically activated gp41Virion with gp41 fusion peptide in insertion complexVirion with gp41 forming hairpin structureViral core surrounded by Matrix layerEncapsidated viral coreuncoated viral complexRTC (Reverse Transcription Complex) with RNA templateRTC with tRNA primer:RNA templateRTC with minus sssDNA:tRNA primer:RNA templateRTC with nicked minus sssDNA:tRNA primer:RNA templateRTC with degraded RNA template and minus sssDNARTC with minus sssDNA transferred to 3'-end of viral RNA templateRTC with minus strand DNA synthesis initiated from 3'-endRTC with extensive RNase-H digestionRTC with extending minus strand DNARTC with extending second-strand DNARTC without viral RNA templateRTC with annealed complementary PBS seqments in +sssDNA and -strand DNARTC with duplex DNA containing discontinuous plus strand flapRTC with integration competent viral DNAAssembling HIV virionImmature HIV virionRTC with minus sssDNA containing deaminated C residues:tRNA primer:RNA templatePlatelet releasate (inferred) cytosolic proteinsPlatelet releasate (inferred) cytosolic proteins [extracellular region]BSG:PPIACyclophilin A:Cyclosporin AFicolin-rich granule lumen proteinsFicolin-rich granule lumen proteins [extracellular region]Secretory granule lumen proteinsSecretory granule lumen proteins [extracellular region]Formation of Pre-Integration Complex (PIC)Packaging of HIV virion on the host cell plasma membraneBasigin binds CyPAExpression of Peptidyl-prolyl cis-trans isomerase A
P527
P688
Cyclophilin A regulates HIV-1 infectivity, as demonstrated by gene targeting in human T cellsInhibition of cyclophilins alters lipid trafficking and blocks hepatitis C virus secretionEnzymatic and structural characterization of non-peptide ligand-cyclophilin complexesCyclophilin A, the major intracellular receptor for the immunosuppressant cyclosporin A, maps to chromosome 7p11.2-p13: four pseudogenes map to chromosomes 3, 10, 14, and 18Cloning, expression, and purification of human cyclophilin in Escherichia coli and assessment of the catalytic role of cysteines by site-directed mutagenesisMultiple cyclophilins involved in different cellular pathways mediate HCV replicationPeptidyl-prolyl cis-trans isomerase is the cyclosporin A-binding protein cyclophilinCrystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexesCrystal structure of human calcineurin complexed with cyclosporin A and human cyclophilinGenetic deficiency and polymorphisms of cyclophilin A reveal its essential role for Human Coronavirus 229E replication.
P921
Q50256448-FA243393-4AF1-4C40-962A-F90C7F94491BQ50256456-D0109636-38F8-4495-A891-8352D331B822Q50256459-F04CCB4E-131C-46EC-8D19-D6B718E92BB9Q50256464-D69BE512-7625-440F-824D-D336ED2AA448Q50256466-390502ED-D840-493B-81F2-7264000FC59BQ50256472-48E1ED74-C9FF-41CF-B285-7B994D6352C8Q50256478-F3D38BB6-272F-4D78-A704-6EDDB23C7356Q50256484-DDEC68FC-0849-43E0-983E-AF90EB6419DFQ50256489-859C2F29-E7EE-4F34-8102-76E29A031CD3Q50256494-C8C7C85C-C711-41E7-9CAA-C029EBF28E1FQ50256497-C4792534-27AE-4161-B844-CE53E7456FE3Q50256498-9E1EEB8E-038C-4E43-BD34-249ABEDA4668Q50256499-70079764-7D11-45AF-B3DB-58167C5E56F7Q50256501-2B0271E8-6E48-4650-AFF8-38697D5EA7CEQ50256504-C0147027-F01B-46B7-A994-681ED9B74611Q50256506-93371CF0-C3F2-49FF-A377-7D33D056EAE9Q50256509-6F027D90-D579-4AFB-8BC8-E07C9559D33EQ50256511-91EEDC87-CCB1-43AA-ACE3-A817C9406CBFQ50256512-F48B0355-23C6-4544-8BB6-271EC028B59FQ50256514-2CB7A322-5888-4D9B-92D7-6401A44D8634Q50256516-DA6D3477-A3CB-4635-9FD1-550A11585FACQ50256517-DA23F32F-2D0B-49F6-8C18-50487223B4F2Q50256518-5F9DC763-D072-45AA-9852-09DF7C3B72D8Q50256519-AB419D13-50D9-4784-B025-4BBFE569D942Q50256520-0848B838-F2C6-495E-97F7-FC5D876AED49Q50256654-89639B7C-BB2E-4E60-9B65-AA1C4FA072E8Q50256658-60161CD9-4791-4262-A93A-A00245440DB0Q50256676-C058F4B0-1E0E-4903-96F2-30565B59BD6FQ50259239-EFC95B06-2C42-492F-B7AE-AF9879DE4E86Q50259240-5589F3CB-AB4A-4951-A8C9-15D797587B49Q50259469-BBF43668-93C5-486E-9E40-3CCBF3EA702EQ50260134-0713450F-A0DD-46B6-977A-117BB06EC709Q50262418-5D4775B3-B277-4045-922C-24D83A754C13Q50262422-EF009959-DB94-4277-875D-82996C2CD069Q50262429-E4FE8B8E-3BCA-485B-A94D-7800BB32C810Q50262432-E5559D96-F982-4C63-8B43-47A3BB9A08C7Q50289291-D5F00C88-3A95-4CBF-BE4F-5016E272A349Q50289398-55B3AC02-F7C6-4A39-A893-6AC32F765B42Q50291301-03EB1A0B-8619-4B2E-9A33-1028A2C1E48EQ50292827-C5BAFA26-E521-4F1F-82C5-25F2DF663D90
P527
Q24290922-8FC2FFCC-B628-4D2C-97B8-2AD717AEEB87Q24308039-C03E8C99-0D20-4451-A180-436C94EE20CBQ24313475-65D0F0FF-E292-4CCA-94AD-A32109A12734Q24314870-31819DAD-6A22-41F7-8025-264EEEAD617BQ24317548-5A1F80B7-64FC-47A2-AB22-35C15432F97FQ24319590-5A47E22F-D4A8-4F62-AA3E-CAB7448A17CFQ24338951-1226009B-1A69-42D0-80B6-BBFE4027906EQ24535752-EFEEA651-3E5E-435A-A947-881D47FABB7EQ24536083-E8E99AA1-3444-4BC8-9F5F-BA618DF67342Q38576023-af7126be-40b9-081a-21e4-1ad1b8960055
P921
description
humanes Protein
@de
mammalian protein found in Homo sapiens
@en
menselijk eiwit
@nl
protein
@id
proteinë
@sq
protèin
@ace
protéine humaine
@fr
بروتين بشري
@ar
name
Peptidylprolyl isomerase A
@en
Peptidylprolyl isomerase A
@nl
type
label
Peptidylprolyl isomerase A
@en
Peptidylprolyl isomerase A
@nl
altLabel
Cyclophilin A
@en
PPIA
@en
PPIase A
@en
T cell cyclophilin
@en
cyclosporin A-binding protein
@en
epididymis secretory sperm binding protein Li 69p
@en
peptidyl-prolyl cis-trans isomerase A
@en
peptidylprolyl isomerase A (cyclophilin A)
@en
rotamase A
@en
prefLabel
Peptidylprolyl isomerase A
@en
Peptidylprolyl isomerase A
@nl
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P527
P637
NP_001287910
XP_024302576
XP_024302577
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ENSP00000394670
ENSP00000405975
ENSP00000419425
ENSP00000427976
ENSP00000429251
ENSP00000430817
ENSP00000479961