Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer
about
Centrosome dysfunction contributes to chromosome instability, chromoanagenesis, and genome reprograming in cancerMelanoma genome sequencing reveals frequent PREX2 mutationsThe genomic and transcriptomic landscape of a HeLa cell lineHigh-throughput sequencing for biology and medicineVisualizing multidimensional cancer genomics dataChromothripsis, an unexpected novel form of complexity for chromosomal rearrangementsThe quiescent cellular state is Arf/p53-dependent and associated with H2AX downregulation and genome stabilityStructural variation discovery in the cancer genome using next generation sequencing: computational solutions and perspectivesSugar and chromosome stability: clastogenic effects of sugars in vitamin B6-deficient cellsTargeted Cancer Therapy: Vital Oncogenes and a New Molecular Genetic Paradigm for Cancer Initiation Progression and TreatmentPeSV-Fisher: identification of somatic and non-somatic structural variants using next generation sequencing dataFrequent Somatic Mutation in Adult Intestinal Stem Cells Drives Neoplasia and Genetic Mosaicism during AgingMechanisms for Structural Variation in the Human GenomeBreakpoint profiling of 64 cancer genomes reveals numerous complex rearrangements spawned by homology-independent mechanisms.Reanalysis of RNA-sequencing data reveals several additional fusion genes with multiple isoforms.The elusive evidence for chromothripsisChromothripsis and human disease: piecing together the shattering process.Shattered and stitched chromosomes-chromothripsis and chromoanasynthesis-manifestations of a new chromosome crisis?Chromothripsis: breakage-fusion-bridge over and over again.MultiNotch MS3 enables accurate, sensitive, and multiplexed detection of differential expression across cancer cell line proteomes.Improving mammalian genome scaffolding using large insert mate-pair next-generation sequencing.Cytogenetically normal uterine leiomyomas without MED12-mutations - a source to identify unknown mechanisms of the development of uterine smooth muscle tumors.Breakpoint features of genomic rearrangements in neuroblastoma with unbalanced translocations and chromothripsis.Chromosomal copy number aberrations in colorectal metastases resemble their primary counterparts and differences are typically non-recurrentShatterProof: operational detection and quantification of chromothripsis.Chromosome-breakage genomic instability and chromothripsis in breast cancerCell Fusion Connects Oncogenesis with Tumor Evolution.Chromothripsis and focal copy number alterations determine poor outcome in malignant melanomaWhole genome sequence analysis links chromothripsis to EGFR, MDM2, MDM4, and CDK4 amplification in glioblastoma.Losing balance: the origin and impact of aneuploidy in cancerIntra-patient Inter-metastatic Genetic Heterogeneity in Colorectal Cancer as a Key Determinant of Survival after Curative Liver Resection.Chromothripsis Is a Recurrent Genomic Abnormality in High-Risk Myelodysplastic Syndromes.Functionally-focused algorithmic analysis of high resolution microarray-CGH genomic landscapes demonstrates comparable genomic copy number aberrations in MSI and MSS sporadic colorectal cancer.Defining the diverse spectrum of inversions, complex structural variation, and chromothripsis in the morbid human genome.Translesion Polymerases Drive Microhomology-Mediated Break-Induced Replication Leading to Complex Chromosomal Rearrangements.Clonal origins and parallel evolution of regionally synchronous colorectal adenoma and carcinomaMammalian chromosomes contain cis-acting elements that control replication timing, mitotic condensation, and stability of entire chromosomes.Remarkable similarities of chromosomal rearrangements between primary human breast cancers and matched distant metastases as revealed by whole-genome sequencingChromosomal catastrophe is a frequent event in clinically insignificant prostate cancer.Functional genomic analysis of chromosomal aberrations in a compendium of 8000 cancer genomes.
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P2860
Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer
description
2011 nî lūn-bûn
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2011 թուականին հրատարակուած գիտական յօդուած
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2011 թվականին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年论文
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name
Chromothripsis is a common mec ...... d metastatic colorectal cancer
@ast
Chromothripsis is a common mec ...... d metastatic colorectal cancer
@en
Chromothripsis is a common mec ...... d metastatic colorectal cancer
@en-gb
Chromothripsis is a common mec ...... d metastatic colorectal cancer
@nl
type
label
Chromothripsis is a common mec ...... d metastatic colorectal cancer
@ast
Chromothripsis is a common mec ...... d metastatic colorectal cancer
@en
Chromothripsis is a common mec ...... d metastatic colorectal cancer
@en-gb
Chromothripsis is a common mec ...... d metastatic colorectal cancer
@nl
prefLabel
Chromothripsis is a common mec ...... d metastatic colorectal cancer
@ast
Chromothripsis is a common mec ...... d metastatic colorectal cancer
@en
Chromothripsis is a common mec ...... d metastatic colorectal cancer
@en-gb
Chromothripsis is a common mec ...... d metastatic colorectal cancer
@nl
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P3181
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P1476
Chromothripsis is a common mec ...... d metastatic colorectal cancer
@en
P2093
Emile Voest
Ivo Renkens
Joost S Vermaat
Marco Koudijs
Markus J van Roosmalen
Masoumeh Tavakoli-Yaraki
Oscar Paling
Ruben van 't Slot
Stef van Lieshout
Wigard P Kloosterman
P2860
P2888
P3181
P356
10.1186/GB-2011-12-10-R103
P407
P577
2011-01-01T00:00:00Z
P5875
P6179
1051100601