Genome-wide assessment of the carriers involved in the cellular uptake of drugs: a model system in yeast
about
How drugs get into cells: tested and testable predictions to help discriminate between transporter-mediated uptake and lipoidal bilayer diffusionFitting Transporter Activities to Cellular Drug Concentrations and Fluxes: Why the Bumblebee Can FlyMetabolomics and systems pharmacology: why and how to model the human metabolic network for drug discoveryThe metabolome 18 years on: a concept comes of ageMetMaxStruct: A Tversky-Similarity-Based Strategy for Analysing the (Sub)Structural Similarities of Drugs and Endogenous MetabolitesThe genetic control of growth rate: a systems biology study in yeast.The yeast sphingolipid signaling landscape.Finding novel pharmaceuticals in the systems biology era using multiple effective drug targets, phenotypic screening and knowledge of transporters: where drug discovery went wrong and how to fix it.An analysis of a 'community-driven' reconstruction of the human metabolic networkcis-Peptide Bonds: A Key for Intestinal Permeability of Peptides? .Genomic profiling of fungal cell wall-interfering compounds: identification of a common gene signature.Enhancing Drug Efficacy and Therapeutic Index through Cheminformatics-Based Selection of Small Molecule Binary Weapons That Improve Transporter-Mediated Targeting: A Cytotoxicity System Based on Gemcitabine.The solute carrier SLC35F2 enables YM155-mediated DNA damage toxicity.Predicting complex phenotype-genotype interactions to enable yeast engineering: Saccharomyces cerevisiae as a model organism and a cell factory.Translocation of solutes and proteins across the glycosomal membrane of trypanosomes; possibilities and limitations for targeting with trypanocidal drugs.Understanding transporter specificity and the discrete appearance of channel-like gating domains in transporters.Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently.The apparent permeabilities of Caco-2 cells to marketed drugs: magnitude, and independence from both biophysical properties and endogenite similarities.A mathematical model of microbial folate biosynthesis and utilisation: implications for antifolate development.A 'rule of 0.5' for the metabolite-likeness of approved pharmaceutical drugs.Novel, Synergistic Antifungal Combinations that Target Translation Fidelity.Transporters of Trypanosoma brucei-phylogeny, physiology, pharmacology.
P2860
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P2860
Genome-wide assessment of the carriers involved in the cellular uptake of drugs: a model system in yeast
description
2011 nî lūn-bûn
@nan
2011 թուականին հրատարակուած գիտական յօդուած
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2011 թվականին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
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2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
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name
Genome-wide assessment of the ...... drugs: a model system in yeast
@ast
Genome-wide assessment of the ...... drugs: a model system in yeast
@en
Genome-wide assessment of the ...... drugs: a model system in yeast
@en-gb
Genome-wide assessment of the ...... drugs: a model system in yeast
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type
label
Genome-wide assessment of the ...... drugs: a model system in yeast
@ast
Genome-wide assessment of the ...... drugs: a model system in yeast
@en
Genome-wide assessment of the ...... drugs: a model system in yeast
@en-gb
Genome-wide assessment of the ...... drugs: a model system in yeast
@nl
prefLabel
Genome-wide assessment of the ...... drugs: a model system in yeast
@ast
Genome-wide assessment of the ...... drugs: a model system in yeast
@en
Genome-wide assessment of the ...... drugs: a model system in yeast
@en-gb
Genome-wide assessment of the ...... drugs: a model system in yeast
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P2093
P2860
P50
P3181
P356
P1433
P1476
Genome-wide assessment of the ...... drugs: a model system in yeast
@en
P2093
Harry J Moss
Karin Lanthaler
Paul D Dobson
Stephen G Oliver
P2860
P2888
P3181
P356
10.1186/1741-7007-9-70
P407
P577
2011-10-24T00:00:00Z
P5875
P6179
1005280446