Integrin alpha 2 beta 1 promotes activation of protein phosphatase 2A and dephosphorylation of Akt and glycogen synthase kinase 3 beta.Mammary-derived growth inhibitor (MDGI) interacts with integrin α-subunits and suppresses integrin activity and invasionSCAI acts as a suppressor of cancer cell invasion through the transcriptional control of beta1-integrinCIP2A inhibits PP2A in human malignanciesNegative regulation of EGFR signalling through integrin-alpha1beta1-mediated activation of protein tyrosine phosphatase TCPTPSHARPIN is an endogenous inhibitor of β1-integrin activationSmall GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta1-integrins.Identification of protein interactions involved in cellular signalingFilopodia in cell adhesion, 3D migration and cancer cell invasionFilopodia and adhesion in cancer cell motilityA ZO-1/α5β1-integrin complex regulates cytokinesis downstream of PKCε in NCI-H460 cells plated on fibronectinBeta 1-integrin-c-Met cooperation reveals an inside-in survival signalling on autophagy-related endomembranes.Selective integrin endocytosis is driven by interactions between the integrin α-chain and AP2.The complexity of integrins in cancer and new scopes for therapeutic targetingPKCepsilon-mediated phosphorylation of vimentin controls integrin recycling and motilityDistinct recognition of collagen subtypes by alpha(1)beta(1) and alpha(2)beta(1) integrins. Alpha(1)beta(1) mediates cell adhesion to type XIII collagenClustering induces a lateral redistribution of alpha 2 beta 1 integrin from membrane rafts to caveolae and subsequent protein kinase C-dependent internalization.Cytokinesis failure due to derailed integrin traffic induces aneuploidy and oncogenic transformation in vitro and in vivo.Mutant p53-associated myosin-X upregulation promotes breast cancer invasion and metastasis.L-type calcium channels regulate filopodia stability and cancer cell invasion downstream of integrin signalling.Inhibition of receptor tyrosine kinase signalling by small molecule agonist of T-cell protein tyrosine phosphatase.Tensin-4-dependent MET stabilization is essential for survival and proliferation in carcinoma cells.Adhesion receptors and cell invasion: mechanisms of integrin-guided degradation of extracellular matrix.Molecular mechanism of T-cell protein tyrosine phosphatase (TCPTP) activation by mitoxantrone.Integrin-specific control of focal adhesion kinase and RhoA regulates membrane protrusion and invasion.CIP2A is associated with human breast cancer aggressivity.Endothelial destabilization by angiopoietin-2 via integrin β1 activation.Integrin-protein kinase C relationships.Competitive binding of Rab21 and p120RasGAP to integrins regulates receptor traffic and migration.Distinct c-Met activation mechanisms induce cell rounding or invasion through pathways involving integrins, RhoA and HIP1.Calpains promote α2β1 integrin turnover in nonrecycling integrin pathwayMutually Exclusive Roles of SHARPIN in Integrin Inactivation and NF-κB Signaling.The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signalingNovel functions of vimentin in cell adhesion, migration, and signaling.Integrin endosomal signalling suppresses anoikis.Vimentin coordinates fibroblast proliferation and keratinocyte differentiation in wound healing via TGF-β-Slug signaling.Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription.SHARPIN regulates uropod detachment in migrating lymphocytes.Interplay between cell adhesion and growth factor receptors: from the plasma membrane to the endosomes.High-throughput methods in identification of protein tyrosine phosphatase inhibitors and activators.
P50
Q24292286-70D9C71D-2EC6-409F-8860-AC906F6AB1FDQ24297961-CDE36445-D7FB-4E99-813E-E0C640EBD3DEQ24313465-097E33F9-917D-4EEF-B201-1BC129E0980EQ24319683-0395A0E4-8879-47FC-96E8-BF3B0C320236Q24321559-AD8E91AE-E59F-4A8C-902B-EB62F75CAE96Q24338618-03C56560-CAC9-4417-A114-32F7CEEA4B71Q24338894-7212C86F-C3E9-45E6-8653-CE7AF5274E86Q24601574-AC5930B3-A332-4DF4-8F77-2BD70B58D452Q26799486-7F5D1016-0C36-4AFD-8D9F-23036FB9B9CEQ26823315-6926BB13-6D7D-4505-A6D3-491C5D231C81Q27310167-D6F63741-E0ED-4A54-98E2-2855D4F18CCBQ27342529-A6663307-26A6-4F42-BAC3-179F0B564676Q27703631-2C784AF5-DA04-4EF2-A722-FEB1D30F9B03Q28073343-9152AB44-6BC1-42BD-A21E-74B07EE7970CQ28512303-86C3204C-F624-471A-A077-652B88D1BA44Q28647122-BC081761-6B57-4DE5-8886-35FB1F22AE24Q30506115-C02C0D02-43A6-4B90-AE6B-E3D17D855DAFQ30524194-2FD57861-90AC-46B2-901F-9C2532A21035Q30572690-D59CF33D-7BA2-472E-86EF-A3F12DF7261BQ30831376-2CBBFB62-9412-4AC4-8497-AB2866F756D5Q30976460-36760C99-22F5-400C-90E6-1B03651641F8Q33984904-B861A07C-436E-4B38-860A-02DAFDFA8A96Q34008810-BD679014-D3C8-49BB-AAB2-0FF4C81F1FA7Q34821703-2F47DC01-228F-461D-A247-21EFFB48E77CQ34990234-86C58AC9-7E8B-4607-9D3C-673A86638682Q34996768-2AC6544C-D7FA-4650-B61D-5ABC5D9A6FDFQ35047913-D1A6F016-82B0-4BCD-8330-D186266A9EFFQ35052933-ED655A9E-AC08-444C-B27C-8D4DBE1F55D7Q35130176-3973B9E4-9DEF-4ECA-8312-36B93F4C1AA5Q35162043-D82A48AD-21D1-4CB7-91AB-DA70FB0EEEC3Q35712174-F7F46C27-2E03-4417-9D42-CCFF811323EBQ35850779-E04E7BFD-FF58-4619-A7B2-E678EF6FCED4Q36294561-CF277F98-DD1D-4F7E-A915-760D35F7157CQ36826640-81B40BDE-FCC2-4AFF-A439-9C9E85AF46E9Q36961276-132565C6-B4E5-441A-A5A3-32740427E603Q37142732-54D59CB4-9D6D-4136-BC1B-E16C7CB63CA5Q37157064-09CD94E4-A2A2-4371-83DF-E6000371CA53Q37366883-44E2438A-14BA-4EF4-A638-BA8959DDF023Q37590219-BC75D78D-F350-4968-9C93-4D8B1D4952A3Q37834675-2B048A72-238C-44DD-9860-1890036D82B9
P50
description
Finnish molecular cell biologi ...... professor (Academy of Finland)
@en
Fins moleculair biologe
@nl
finnische Molekularzellbiologin
@de
suomalainen molekyylaarisen so ...... iaprofessori (Suomen Akatemia)
@fi
name
Johanna Ivaska
@ast
Johanna Ivaska
@ca
Johanna Ivaska
@de
Johanna Ivaska
@en
Johanna Ivaska
@es
Johanna Ivaska
@fi
Johanna Ivaska
@fr
Johanna Ivaska
@ga
Johanna Ivaska
@nl
Johanna Ivaska
@sl
type
label
Johanna Ivaska
@ast
Johanna Ivaska
@ca
Johanna Ivaska
@de
Johanna Ivaska
@en
Johanna Ivaska
@es
Johanna Ivaska
@fi
Johanna Ivaska
@fr
Johanna Ivaska
@ga
Johanna Ivaska
@nl
Johanna Ivaska
@sl
prefLabel
Johanna Ivaska
@ast
Johanna Ivaska
@ca
Johanna Ivaska
@de
Johanna Ivaska
@en
Johanna Ivaska
@es
Johanna Ivaska
@fi
Johanna Ivaska
@fr
Johanna Ivaska
@ga
Johanna Ivaska
@nl
Johanna Ivaska
@sl
P108
P1960
j-Wd_H8AAAAJ
P2080
P21
P27
P31
P496
0000-0002-6295-6556
P569
1972-01-01T00:00:00Z