SHARPIN regulates uropod detachment in migrating lymphocytes. - Test2 - elhamkhani - TriplyDB

SHARPIN regulates uropod detachment in migrating lymphocytes.

SHARPIN regulates uropod detachment in migrating lymphocytes.

http://www.wikidata.org/entity/Q37366883

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T Lymphocyte Migration: An Action Movie Starring the Actin and Associated Actors.Linear ubiquitination signals in adaptive immune responses Leukocyte adhesion and polarization: Role of glycosylphosphatidylinositol-anchored proteins Elevation of SIPL1 (SHARPIN) Increases Breast Cancer Risk Mutually Exclusive Roles of SHARPIN in Integrin Inactivation and NF-κB Signaling.SHARPIN controls regulatory T cells by negatively modulating the T cell antigen receptor complex Roles of linear ubiquitinylation, a crucial regulator of NF-κB and cell death, in the immune system.Structural basis of blocking integrin activation and deactivation for anti-inflammation The Sharpin interactome reveals a role for Sharpin in lamellipodium formation via the Arp2/3 complex.SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras.Leading from the Back: The Role of the Uropod in Neutrophil Polarization and Migration.SHARPIN regulates collagen architecture and ductal outgrowth in the developing mouse mammary gland.Signatures derived from increase in SHARPIN gene copy number are associated with poor prognosis in patients with breast cancer.Integrin beta 1 inhibition alleviates the chronic hyperproliferative dermatitis phenotype of SHARPIN-deficient mice.

P2860

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P2860

SHARPIN regulates uropod detachment in migrating lymphocytes.

http://www.wikidata.org/entity/Q37366883

description

2013 nî lūn-bûn

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2013年の論文

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2013年学术文章

@wuu

2013年学术文章

@zh-cn

2013年学术文章

@zh-hans

2013年学术文章

@zh-my

2013年学术文章

@zh-sg

2013年學術文章

@yue

2013年學術文章

@zh

2013年學術文章

@zh-hant

name

SHARPIN regulates uropod detachment in migrating lymphocytes.

@en

SHARPIN regulates uropod detachment in migrating lymphocytes.

@nl

type

label

SHARPIN regulates uropod detachment in migrating lymphocytes.

@en

SHARPIN regulates uropod detachment in migrating lymphocytes.

@nl

prefLabel

SHARPIN regulates uropod detachment in migrating lymphocytes.

@en

SHARPIN regulates uropod detachment in migrating lymphocytes.

@nl

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SHARPIN regulates uropod detachment in migrating lymphocytes.

@en

P2093

Christopher Potter

http://www.w3.org/2001/XMLSchema#string

Elina Mattila

http://www.w3.org/2001/XMLSchema#string

John P Sundberg

http://www.w3.org/2001/XMLSchema#string

Kaisa Auvinen

http://www.w3.org/2001/XMLSchema#string

Marika Karikoski

http://www.w3.org/2001/XMLSchema#string

Marko Salmi

http://www.w3.org/2001/XMLSchema#string

Nancy Hogg

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P2860

Linear ubiquitination prevents inflammation and regulates immune signalling

SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex

SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis

RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1

Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation

Negative regulation of EGFR signalling through integrin-alpha1beta1-mediated activation of protein tyrosine phosphatase TCPTP

SHARPIN is an endogenous inhibitor of β1-integrin activation

Getting to the site of inflammation: the leukocyte adhesion cascade updated

Integrin-ligand binding properties govern cell migration speed through cell-substratum adhesiveness

A small molecule agonist of an integrin, alphaLbeta2.

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