MID1 and MID2 homo- and heterodimerise to tether the rapamycin-sensitive PP2A regulatory subunit, alpha 4, to microtubules: implications for the clinical variability of X-linked Opitz GBBB syndrome and other developmental disorders
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TRIM16 acts as a tumour suppressor by inhibitory effects on cytoplasmic vimentin and nuclear E2F1 in neuroblastoma cellsCharacterization of a novel, cytokine-inducible carboxypeptidase D isoform in haematopoietic tumour cellsMig12, a novel Opitz syndrome gene product partner, is expressed in the embryonic ventral midline and co-operates with Mid1 to bundle and stabilize microtubulesThe biogenesis of active protein phosphatase 2A holoenzymes: a tightly regulated process creating phosphatase specificityStructural basis of protein phosphatase 2A stable latencyX-linked Opitz syndrome: novel mutations in the MID1 gene and redefinition of the clinical spectrumStructural organization and Zn2+-dependent subdomain interactions involving autoantigenic epitopes in the Ring-B-box-coiled-coil (RBCC) region of Ro52NMR studies of the C-terminus of alpha4 reveal possible mechanism of its interaction with MID1 and protein phosphatase 2ALoss of the novel tumour suppressor and polarity gene Trim62 (Dear1) synergizes with oncogenic Ras in invasive lung cancerDevelopmental expression of alpha4 protein phosphatase regulatory subunit in tissues affected by Opitz syndrome.XLOS-observed mutations of MID1 Bbox1 domain cause domain unfolding.Local pulsatile contractions are an intrinsic property of the myosin 2A motor in the cortical cytoskeleton of adherent cells.Interaction between salt-inducible kinase 2 and protein phosphatase 2A regulates the activity of calcium/calmodulin-dependent protein kinase I and protein phosphatase methylesterase-1.Subclassification of the RBCC/TRIM superfamily reveals a novel motif necessary for microtubule binding.The phosphatase subunit tap42 functions independently of target of rapamycin to regulate cell division and survival in Drosophila.MID1 catalyzes the ubiquitination of protein phosphatase 2A and mutations within its Bbox1 domain disrupt polyubiquitination of alpha4 but not of PP2Ac.Mid1/Mid2 expression in craniofacial development and a literature review of X-linked opitz syndrome.The E3 Ubiquitin Ligase TRIM9 Is a Filopodia Off Switch Required for Netrin-Dependent Axon Guidance.The X-Linked-Intellectual-Disability-Associated Ubiquitin Ligase Mid2 Interacts with Astrin and Regulates Astrin Levels to Promote Cell Division.The MID1 E3 ligase catalyzes the polyubiquitination of Alpha4 (α4), a regulatory subunit of protein phosphatase 2A (PP2A): novel insights into MID1-mediated regulation of PP2A.X-linked microtubule-associated protein, Mid1, regulates axon development.Midline2 is overexpressed and a prognostic indicator in human breast cancer and promotes breast cancer cell proliferation in vitro and in vivo.Disrupted IRF6-NME1/2 Complexes as a Cause of Cleft Lip/Palate.PP2A as a master regulator of the cell cycle.Targeted deep resequencing identifies MID2 mutation for X-linked intellectual disability with varied disease severity in a large kindred from India.Protein phosphatase 2A (PP2A)-specific ubiquitin ligase MID1 is a sequence-dependent regulator of translation efficiency controlling 3-phosphoinositide-dependent protein kinase-1 (PDPK-1).Tripartite motif-containing 3 (TRIM3) inhibits tumor growth and metastasis of liver cancer.Expression and subcellular localization of mechano-growth factor in osteoblasts under mechanical stretch.The Opitz syndrome gene product MID1 assembles a microtubule-associated ribonucleoprotein complex.Cross-talk between cytosolic phospholipase A2 alpha (cPLA2 alpha) and secretory phospholipase A2 (sPLA2) in hydrogen peroxide-induced arachidonic acid release in murine mesangial cells: sPLA2 regulates cPLA2 alpha activity that is responsible for arProteomic analysis reveals novel ligands and substrates for LNX1 E3 ubiquitin ligase.Update on 13 Syndromes Affecting Craniofacial and Dental Structures.Circulating endothelial microparticles in acute ischemic stroke: a link to severity, lesion volume and outcome.Relationship between genotype and arcuate fasciculus morphology in six young children with global developmental delay: Preliminary DTI stuy.The contribution of RING and B-box 2 domains to retroviral restriction mediated by monkey TRIM5alpha.MID2 can substitute for MID1 and control exocytosis of lytic granules in cytotoxic T cells
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P2860
MID1 and MID2 homo- and heterodimerise to tether the rapamycin-sensitive PP2A regulatory subunit, alpha 4, to microtubules: implications for the clinical variability of X-linked Opitz GBBB syndrome and other developmental disorders
description
2002 nî lūn-bûn
@nan
2002 թուականին հրատարակուած գիտական յօդուած
@hyw
2002 թվականին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
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name
MID1 and MID2 homo- and hetero ...... other developmental disorders
@ast
MID1 and MID2 homo- and hetero ...... other developmental disorders
@en
MID1 and MID2 homo- and hetero ...... other developmental disorders
@en-gb
MID1 and MID2 homo- and hetero ...... other developmental disorders
@nl
type
label
MID1 and MID2 homo- and hetero ...... other developmental disorders
@ast
MID1 and MID2 homo- and hetero ...... other developmental disorders
@en
MID1 and MID2 homo- and hetero ...... other developmental disorders
@en-gb
MID1 and MID2 homo- and hetero ...... other developmental disorders
@nl
prefLabel
MID1 and MID2 homo- and hetero ...... other developmental disorders
@ast
MID1 and MID2 homo- and hetero ...... other developmental disorders
@en
MID1 and MID2 homo- and hetero ...... other developmental disorders
@en-gb
MID1 and MID2 homo- and hetero ...... other developmental disorders
@nl
P2093
P2860
P921
P356
P1433
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MID1 and MID2 homo- and hetero ...... other developmental disorders
@en
P2093
Blair Hopwood
Timothy C Cox
P2860
P2888
P356
10.1186/1471-2121-3-1
P407
P577
2002-01-01T00:00:00Z
P5875
P6179
1044058342