about
P688
Transcription factor genes Smad4 and Gata4 cooperatively regulate cardiac valve development. [corrected]Skeletal myosin light chain kinase regulates skeletal myogenesis by phosphorylation of MEF2CGATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5Distinct functions are implicated for the GATA-4, -5, and -6 transcription factors in the regulation of intestine epithelial cell differentiationLoss-of-function mutation in GATA4 causes anomalies of human testicular developmentJumonji represses atrial natriuretic factor gene expression by inhibiting transcriptional activities of cardiac transcription factorsTsix RNA and the germline factor, PRDM14, link X reactivation and stem cell reprogrammingHopx and Hdac2 interact to modulate Gata4 acetylation and embryonic cardiac myocyte proliferationProper coronary vascular development and heart morphogenesis depend on interaction of GATA-4 with FOG cofactorsMouse GATA-4: a retinoic acid-inducible GATA-binding transcription factor expressed in endodermally derived tissues and heartTranscription factor GATA-4 regulates cardiac muscle-specific expression of the alpha-myosin heavy-chain geneLoss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in miceDefects of the heart, eye, and megakaryocytes in peroxisome proliferator activator receptor-binding protein (PBP) null embryos implicate GATA family of transcription factorsCooperative and antagonistic interactions between Sall4 and Tbx5 pattern the mouse limb and heartExpression and hormonal regulation of transcription factors GATA-4 and GATA-6 in the mouse ovaryDistinct gene expression patterns in skeletal and cardiac muscle are dependent on common regulatory sequences in the MLC1/3 locusThe cardiac tissue-restricted homeobox protein Csx/Nkx2.5 physically associates with the zinc finger protein GATA4 and cooperatively activates atrial natriuretic factor gene expression.GATA4 is a dosage-sensitive regulator of cardiac morphogenesisGATA factors lie upstream of Nkx 2.5 in the transcriptional regulatory cascade that effects cardiogenesisRetinoic acid receptor gamma activates receptor tyrosine kinase Tie1 gene transcription through transcription factor GATA4 in F9 stem cellsDifferential expression and function of Tbx5 and Tbx20 in cardiac developmentSOX7 and GATA-4 are competitive activators of Fgf-3 transcriptionGata4 is necessary for normal pulmonary lobar developmentThe primitive endoderm lineage of the mouse blastocyst: sequential transcription factor activation and regulation of differentiation by Sox17.Cardiomyocyte GATA4 functions as a stress-responsive regulator of angiogenesis in the murine heartMorphogenesis of the right ventricle requires myocardial expression of Gata4Spectrum of heart disease associated with murine and human GATA4 mutationCardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heartGata4 is essential for the maintenance of jejunal-ileal identities in the adult mouse small intestineGATA4 regulates Sertoli cell function and fertility in adult male miceThe transcription factor GATA-6 regulates pathological cardiac hypertrophyTargeted mutagenesis of the transcription factor GATA-4 gene in mouse embryonic stem cells disrupts visceral endoderm differentiation in vitroThe cardiac transcription network modulated by Gata4, Mef2a, Nkx2.5, Srf, histone modifications, and microRNAsThe tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryoThe zinc finger-containing transcription factor Gata-4 is expressed in the developing endocrine pancreas and activates glucagon gene expressionGATA-4:FOG interactions regulate gastric epithelial development in the mouseExosomes secreted from GATA-4 overexpressing mesenchymal stem cells serve as a reservoir of anti-apoptotic microRNAs for cardioprotectionSox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewalAnalysis of the signals and mechanisms mediating nuclear trafficking of GATA-4. Loss of DNA binding is associated with localization in intranuclear specklesGATA4 transcription factor is required for ventral morphogenesis and heart tube formation
P921
Q24293493-D77EFFF1-99A8-47B4-9D70-403CAA7F951BQ24301871-6067BB82-9FFA-4E6F-B6FA-317DED8F896EQ24307366-3ED4490F-0F95-4944-874D-5FACBDE4CCE7Q24311118-328C9E08-08DC-438E-AD1C-DBF68D613A3FQ24336463-F647B11C-26DB-406C-AE9C-553F83FE6801Q24559996-90B20114-2E22-441A-8767-BA3C371CCC8DQ24595783-D84BE700-035F-45A3-A30C-C47F22D46CB8Q24597593-63147D5A-60FF-4323-8C8F-9DF831368592Q24602111-D54C3185-437C-49D3-8142-FEB1AB7E44ADQ24606117-0147EC19-FB3F-42FA-9D5A-AF7CD250F6FAQ24611410-9E5C16FC-D8A3-4580-AAC3-480D59734F36Q24657983-44362597-E503-4D56-B273-C4B0AE916E66Q28207790-142976A8-5194-456D-84D8-2E752F7678A8Q28289031-89ED2187-0329-4D2B-A3E8-5C8781A3C246Q28504485-EB8EEECF-AF55-4370-BA60-B95B656F925DQ28504737-01803FA6-FF39-43CD-9A7E-88E36BBDACA5Q28504813-A9E3508D-CFF4-4AD1-A2A2-74394B419537Q28506640-D2934344-F40E-468C-80B4-320595C28AD8Q28506898-235EE3D7-A60F-43AC-A2CD-DBA7B73E1A87Q28507572-98F40C6A-3027-4BC4-99FB-827B2AF20E54Q28508533-BF2C4DDA-A60E-461F-84FC-604D425CE893Q28508654-11425569-EC45-48CD-A42C-D4D7A68BAFEAQ28508748-BE60E858-85D3-45F8-8F84-5E015F7688F5Q28509448-E6A7C67E-15E8-41D2-80A9-90201E035AE9Q28509556-402445F4-6378-43D0-B513-D5E7A5F3EE60Q28509654-8AAD0077-B79E-49D5-8622-21C058C737BAQ28509800-7A2529D8-4F8F-4B63-91DE-B66182084FFBQ28510052-C48F1EEE-77FD-457F-8174-9D0C00D9994EQ28510344-37C64507-9756-48AF-B21C-A61D1F80E877Q28510930-42107198-2AFD-4905-B962-9EB7CFEBFE69Q28512555-E3AFFB86-2D98-4B7F-9135-3E0C6A151815Q28512577-28EF0BEE-0642-4F91-A950-FC8C4A15B50DQ28512635-2242195C-B007-4C68-AEE6-B0E03B0E4D03Q28512702-BA4B53C1-ACA5-4157-85B2-1C1A059EC539Q28512905-6A31BD86-985B-404A-A2D6-711C1046F9D7Q28513592-206CF4A7-4BBE-4B90-9509-900E6AB0F833Q28576809-B70C2950-07D0-4EF1-B9D6-46D5577EFA34Q28585188-C57D29E6-0947-4A1F-B52E-405C9838FB13Q28585947-545A6BEA-736A-4B6D-AF9A-BB5261906434Q28586495-4D0FB4CE-3377-4DD1-A1B7-9F272FE8005F
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
proteinë
@sq
proteïne in GATA binding protein 4
@nl
protèin
@ace
بروتين في فأر المنازل
@ar
name
GATA binding protein 4
@en
type
label
GATA binding protein 4
@en
altLabel
GATA-binding factor 4
@en
Gata4
@en
transcription factor GATA-4
@en
prefLabel
GATA binding protein 4
@en
P637
P680
P681
P682
P705
P352
P279
P31
P352
P637
NP_001297539
XP_011243258
XP_011243259
P680
P681
P682
P702
P703
P705
ENSMUSP00000066927
ENSMUSP00000113451
ENSMUSP00000113891
ENSMUSP00000114279
ENSMUSP00000114369
ENSMUSP00000121008