GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5
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8p23.1 duplication syndrome differentiated from copy number variation of the defensin cluster at prenatal diagnosis in four new familiesA role for Tbx5 in proepicardial cell migration during cardiogenesisTranscription factor genes Smad4 and Gata4 cooperatively regulate cardiac valve development. [corrected]Mutation in myosin heavy chain 6 causes atrial septal defectAlpha-cardiac actin mutations produce atrial septal defectsHairy-related transcription factors inhibit GATA-dependent cardiac gene expression through a signal-responsive mechanismThe Kruppel-like transcription factor KLF13 is a novel regulator of heart developmentMutations in NOTCH1 cause aortic valve diseaseCommon variation in ISL1 confers genetic susceptibility for human congenital heart diseaseA gain-of-function TBX20 mutation causes congenital atrial septal defects, patent foramen ovale and cardiac valve defectsEvidence by expression analysis of candidate genes for congenital heart defects in the NF1 microdeletion intervalGATA4 loss-of-function mutations underlie familial tetralogy of fallotGATA6 mutations cause human cardiac outflow tract defects by disrupting semaphorin-plexin signalingMutations in cardiac T-box factor gene TBX20 are associated with diverse cardiac pathologies, including defects of septation and valvulogenesis and cardiomyopathyRegulation of cardiac specific nkx2.5 gene activity by small ubiquitin-like modifierLoss-of-function mutation in GATA4 causes anomalies of human testicular developmentHey basic helix-loop-helix transcription factors are repressors of GATA4 and GATA6 and restrict expression of the GATA target gene ANF in fetal heartsTbx20 regulates a genetic program essential to adult mouse cardiomyocyte functionDECIPHER: Database of Chromosomal Imbalance and Phenotype in Humans Using Ensembl ResourcesChromosome 8p23.1 deletions as a cause of complex congenital heart defects and diaphragmatic herniaIdentification of cardiac malformations in mice lacking Ptdsr using a novel high-throughput magnetic resonance imaging techniqueDefining the role of essential genes in human diseaseCytogenomic Aberrations in Congenital Cardiovascular MalformationsGenetic testing in congenital heart disease: A clinical approachGenetics of congenital heart disease: the glass half emptyInvestigating the transcriptional control of cardiovascular developmentOf mice and men: molecular genetics of congenital heart diseaseGenetics of valvular heart diseaseFrom cardiac tissue engineering to heart-on-a-chip: beating challengesKrüppel-like factor 2 is required for normal mouse cardiac developmentCrystal Structure of the Human NKX2.5 Homeodomain in Complex with DNA TargetMammalian sex determination—insights from humans and mice.Development of heart valves requires Gata4 expression in endothelial-derived cellsWhat Is New in Genetics of Congenital Heart Defects?Functional Analysis of Two Novel Mutations in TWIST1 Protein Motifs Found in Ventricular Septal Defect PatientsCooperative and antagonistic interactions between Sall4 and Tbx5 pattern the mouse limb and heartThymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repairCongenital heart disease-causing Gata4 mutation displays functional deficits in vivoUTX and UTY demonstrate histone demethylase-independent function in mouse embryonic developmentDifferential expression and function of Tbx5 and Tbx20 in cardiac development
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GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5
description
2003 nî lūn-bûn
@nan
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年学术文章
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2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
name
GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5
@ast
GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5
@en
GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5
@en-gb
GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5
@nl
type
label
GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5
@ast
GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5
@en
GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5
@en-gb
GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5
@nl
prefLabel
GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5
@ast
GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5
@en
GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5
@en-gb
GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5
@nl
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GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5
@en
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Caryn R Rothrock
Cheryl A Butler
Deepak Srivastava
Irfan S Kathiriya
Isabelle N King
Jonathan C Cohen
Kayoko Hirayama-Yamada
Kunitaka Joo
Marie K Schluterman
Reenu S Eapen
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10.1038/NATURE01827
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2003-07-24T00:00:00Z
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1053582075