Novel chikungunya vaccine candidate with an IRES-based attenuation and host range alteration mechanism
about
Antiviral perspectives for chikungunya virusCharacterization of a Novel Murine Model to Study Zika VirusCross-protective immunity against o'nyong-nyong virus afforded by a novel recombinant chikungunya vaccineThe role of innate versus adaptive immune responses in a mouse model of O'nyong-nyong virus infectionExtended Preclinical Safety, Efficacy and Stability Testing of a Live-attenuated Chikungunya Vaccine CandidateA novel dengue virus detection method that couples DNAzyme and gold nanoparticle approachesA vaccine candidate for eastern equine encephalitis virus based on IRES-mediated attenuationLong-Term Arthralgia after Mayaro Virus Infection Correlates with Sustained Pro-inflammatory Cytokine ResponseIdentifying the Role of E2 Domains on Alphavirus Neutralization and Protective Immune ResponsesDNA vaccine initiates replication of live attenuated chikungunya virus in vitro and elicits protective immune response in micePrime-boost immunization strategies against Chikungunya virusChikungunya vaccines in developmentThe Global Virus Network: Challenging chikungunyaA chikungunya fever vaccine utilizing an insect-specific virus platformChikungunya virus: epidemiology, replication, disease mechanisms, and prospective intervention strategies.Development of Vaccines for Chikungunya Fever.Animal Models of Chikungunya Virus Infection and Disease.Next generation sequencing of DNA-launched Chikungunya vaccine virus.Early neutralizing IgG response to Chikungunya virus in infected patients targets a dominant linear epitope on the E2 glycoprotein.A small antigenic determinant of the Chikungunya virus E2 protein is sufficient to induce neutralizing antibodies which are partially protective in miceSynergistic Internal Ribosome Entry Site/MicroRNA-Based Approach for Flavivirus Attenuation and Live Vaccine Development.Chikungunya vaccine candidate is highly attenuated and protects nonhuman primates against telemetrically monitored disease following a single dose.Therapeutic administration of a recombinant human monoclonal antibody reduces the severity of chikungunya virus disease in rhesus macaques.A novel MVA vectored Chikungunya virus vaccine elicits protective immunity in mice.A novel live-attenuated vaccine candidate for mayaro Fever.Attenuation of Chikungunya virus vaccine strain 181/clone 25 is determined by two amino acid substitutions in the E2 envelope glycoprotein.Novel attenuated Chikungunya vaccine candidates elicit protective immunity in C57BL/6 mice.Expression of plasmid-based shRNA against the E1 and nsP1 genes effectively silenced Chikungunya virus replicationEffective chikungunya virus-like particle vaccine produced in insect cells.IRES-driven expression of the capsid protein of the Venezuelan equine encephalitis virus TC-83 vaccine strain increases its attenuation and safetyCD8+ T cells control Ross River virus infection in musculoskeletal tissues of infected mice.Control of the rescue and replication of Semliki Forest virus recombinants by the insertion of miRNA target sequences.Recombinant modified vaccinia virus Ankara expressing glycoprotein E2 of Chikungunya virus protects AG129 mice against lethal challenge.Chikungunya virus: evolution and genetic determinants of emergence.IFIT1 Differentially Interferes with Translation and Replication of Alphavirus Genomes and Promotes Induction of Type I InterferonHigh rate of subclinical chikungunya virus infection and association of neutralizing antibody with protection in a prospective cohort in the Philippines.A Rodent Model of Chikungunya Virus Infection in RAG1 -/- Mice, with Features of Persistence, for Vaccine Safety Evaluation.Do we need a vaccine against chikungunya?Antiviral Phosphorodiamidate Morpholino Oligomers are Protective against Chikungunya Virus Infection on Cell-based and Murine ModelsA chimeric vesiculo/alphavirus is an effective alphavirus vaccine
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P2860
Novel chikungunya vaccine candidate with an IRES-based attenuation and host range alteration mechanism
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Novel chikungunya vaccine cand ...... ost range alteration mechanism
@ast
Novel chikungunya vaccine cand ...... ost range alteration mechanism
@en
Novel chikungunya vaccine cand ...... ost range alteration mechanism
@en-gb
Novel chikungunya vaccine cand ...... ost range alteration mechanism
@nl
type
label
Novel chikungunya vaccine cand ...... ost range alteration mechanism
@ast
Novel chikungunya vaccine cand ...... ost range alteration mechanism
@en
Novel chikungunya vaccine cand ...... ost range alteration mechanism
@en-gb
Novel chikungunya vaccine cand ...... ost range alteration mechanism
@nl
altLabel
Novel Chikungunya Vaccine Cand ...... ost Range Alteration Mechanism
@en
prefLabel
Novel chikungunya vaccine cand ...... ost range alteration mechanism
@ast
Novel chikungunya vaccine cand ...... ost range alteration mechanism
@en
Novel chikungunya vaccine cand ...... ost range alteration mechanism
@en-gb
Novel chikungunya vaccine cand ...... ost range alteration mechanism
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P2860
P50
P921
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Novel chikungunya vaccine cand ...... ost range alteration mechanism
@en
P2093
Charalambos D Partidos
Erin M Borland
Kenneth Plante
Robert Seymour
Rodion Gorchakov
P2860
P304
P3181
P356
10.1371/JOURNAL.PPAT.1002142
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P50
P5008
P577
2011-07-01T00:00:00Z