A mouse model for Chikungunya: young age and inefficient type-I interferon signaling are risk factors for severe disease - Test2 - elhamkhani - TriplyDB

A mouse model for Chikungunya: young age and inefficient type-I interferon signaling are risk factors for severe disease

A mouse model for Chikungunya: young age and inefficient type-I interferon signaling are risk factors for severe disease

http://www.wikidata.org/entity/Q21559504

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Antiviral perspectives for chikungunya virus Novel chikungunya vaccine candidate with an IRES-based attenuation and host range alteration mechanism Chikungunya virus-associated long-term arthralgia: a 36-month prospective longitudinal study Cross-protective immunity against o'nyong-nyong virus afforded by a novel recombinant chikungunya vaccine The role of innate versus adaptive immune responses in a mouse model of O'nyong-nyong virus infection Extended Preclinical Safety, Efficacy and Stability Testing of a Live-attenuated Chikungunya Vaccine Candidate The wMel Strain of Wolbachia Reduces Transmission of Chikungunya Virus in Aedes aegypti Chikungunya disease in nonhuman primates involves long-term viral persistence in macrophages Chikungunya virus infection Chikungunya virus nonstructural protein 2 inhibits type I/II interferon-stimulated JAK-STAT signaling Chikungunya virus induces IPS-1-dependent innate immune activation and protein kinase R-independent translational shutoff Probing the attenuation and protective efficacy of a candidate chikungunya virus vaccine in mice with compromised interferon (IFN) signaling Persistent arthralgia induced by Chikungunya virus infection is associated with interleukin-6 and granulocyte macrophage colony-stimulating factor A virus-like particle vaccine for epidemic Chikungunya virus protects nonhuman primates against infection Arbovirus high fidelity variant loses fitness in mosquitoes and mice Type I IFN controls chikungunya virus via its action on nonhematopoietic cells Rainbow trout (Oncorhynchus mykiss) muscle satellite cells are targets of salmonid alphavirus infection Critical role for bone marrow stromal antigen 2 in acute Chikungunya virus infection.Caribbean and La Réunion Chikungunya Virus Isolates Differ in Their Capacity To Induce Proinflammatory Th1 and NK Cell Responses and Acute Joint Pathology Early Events in Chikungunya Virus Infection-From Virus Cell Binding to Membrane Fusion Chikungunya viruses that escape monoclonal antibody therapy are clinically attenuated, stable, and not purified in mosquitoes Multiple immune factors are involved in controlling acute and chronic chikungunya virus infection Dissecting the Role of E2 Protein Domains in Alphavirus Pathogenicity Alphavirus Infection: Host Cell Shut-Off and Inhibition of Antiviral Responses γδ T Cells Play a Protective Role in Chikungunya Virus-Induced Disease Chikungunya vaccines in development A potent neutralizing IgM mAb targeting the N218 epitope on E2 protein protects against Chikungunya virus pathogenesis The Global Virus Network: Challenging chikungunya Neuroinvasion and Inflammation in Viral Central Nervous System Infections Nonhuman Primate Models of Chikungunya Virus Infection and Disease (CHIKV NHP Model)Characterization of chikungunya virus induced host response in a mouse model of viral myositis Lethal antibody enhancement of dengue disease in mice is prevented by Fc modification Inhibition of mTORC1 Enhances the Translation of Chikungunya Proteins via the Activation of the MnK/eIF4E Pathway Real-time whole-body visualization of Chikungunya Virus infection and host interferon response in zebrafish Development of a highly protective combination monoclonal antibody therapy against Chikungunya virus Antigenic Variation of East/Central/South African and Asian Chikungunya Virus Genotypes in Neutralization by Immune Sera Mechanism and role of MCP-1 upregulation upon chikungunya virus infection in human peripheral blood mononuclear cells Multidisciplinary Prospective Study of Mother-to-Child Chikungunya Virus Infections on the Island of La Réunion IL-1β, IL-6, and RANTES as Biomarkers of Chikungunya Severity A Mouse Model for Studying Viscerotropic Disease Caused by Yellow Fever Virus Infection

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A mouse model for Chikungunya: young age and inefficient type-I interferon signaling are risk factors for severe disease

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2008 nî lūn-bûn

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2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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Georges Barau

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Olivier Disson

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Characterization of reemerging chikungunya virus

Genome microevolution of chikungunya viruses causing the Indian Ocean outbreak

Human muscle satellite cells as targets of Chikungunya virus infection

EMERGING AND RESURGING VECTOR-BORNE DISEASES

Functional role of type I and type II interferons in antiviral defense

Chikungunya, an epidemic arbovirosis

Sindbis-group alphavirus replication in periosteum and endosteum of long bones in adult mice.

Alpha/beta interferon protects adult mice from fatal Sindbis virus infection and is an important determinant of cell and tissue tropism

Pathogenesis of in utero infections with abortogenic and non-abortogenic alphaviruses in mice

Vectors of Chikungunya virus in Senegal: current data and transmission cycles.

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5570288

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Chikungunya virus

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