about
P688
MafA is a glucose-regulated and pancreatic beta-cell-specific transcriptional activator for the insulin geneIdentification of PCIF1, a POZ domain protein that inhibits PDX-1 (MODY4) transcriptional activityPancreatic-duodenal homeobox 1 regulates expression of liver receptor homolog 1 during pancreas developmentInsulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylationpdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasisPdx1-related homeodomain transcription factors are distinctly expressed in mouse adult pancreatic isletsPcif1 modulates Pdx1 protein stability and pancreatic β cell function and survival in miceThe nucleosome binding protein HMGN3 modulates the transcription profile of pancreatic beta cells and affects insulin secretionLoss of Myt1 function partially compromises endocrine islet cell differentiation and pancreatic physiological function in the mouseThe forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growthThe morphogenesis of the pancreatic mesenchyme is uncoupled from that of the pancreatic epithelium in IPF1/PDX1-deficient miceSox17 regulates organ lineage segregation of ventral foregut progenitor cellsRole of intrinsic DNA binding specificity in defining target genes of the mammalian transcription factor PDX1Conserved transcriptional regulatory domains of the pdx-1 geneConversion of biliary system to pancreatic tissue in Hes1-deficient miceHepatic nuclear factor 1-alpha directs nucleosomal hyperacetylation to its tissue-specific transcriptional targetsCell-specific expression of glucose-dependent-insulinotropic polypeptide is regulated by the transcription factor PDX-1The homeodomain protein PDX1 is required at mid-pancreatic development for the formation of the exocrine pancreasThe PDX1 homeodomain transcription factor negatively regulates the pancreatic ductal cell-specific keratin 19 promoterTwo conserved domains in PCIF1 mediate interaction with pancreatic transcription factor PDX-1RB regulates pancreas development by stabilizing Pdx1An siRNA screen in pancreatic beta cells reveals a role for Gpr27 in insulin productionPBX1 and MEIS1 up-regulate SOX3 gene expression by direct interaction with a consensus binding site within the basal promoter regionTargeted deletion of a cis-regulatory region reveals differential gene dosage requirements for Pdx1 in foregut organ differentiation and pancreas formation.
P921
Q24309331-7897F458-2074-4547-AE41-437644BDAD54Q24567626-234F1559-E455-452F-A354-9126B85FF14AQ24682440-5A1EF64F-999D-47FE-995F-CD77AE9CE5E9Q28156047-E6C2A1B4-5295-4A07-A41A-053671DD0E73Q28504532-3BB0EE74-C3AC-4683-87F9-C06F85EBAE8DQ28505672-75813EDD-8B16-4765-AFD6-1A4D820F9196Q28506102-EEC2EAD1-9401-4A55-A7EA-5FFA4AF9AA7EQ28507123-6F1F03C2-CE69-44E9-97D1-7B8FC796E779Q28507900-AB163617-C5A7-4A2E-8F07-882D7AA53196Q28508976-AD3077E7-EE79-411C-8573-2E1C9C798C59Q28513142-B35EBFED-1798-4CEB-B7F6-A0558A91CDAEQ28513551-BD706071-7252-4990-AF56-0D43A9E29685Q28585290-17F855DB-BCA2-407D-BA0A-846466967149Q28585823-2B0918C7-BE12-42A1-B39A-C9F7E5BE98D9Q28587229-02AC7DC7-3CD9-429F-B476-3FF32DCA81B3Q28587765-56E5EDFF-FCC9-4457-AD36-0FC4650EB6A6Q28589086-FA6E58DB-7370-4035-9019-20820F41A4AAQ28589516-9EC9125E-0EB3-4A2B-BD68-F117B3BB2BEAQ28590960-148F7DC2-342C-433F-89C1-ED6DFEFF2198Q28591307-0E7D5C7A-4A87-4E0F-8F93-F40A9C9F3A99Q28592305-7124BED9-8E14-4FA0-B64A-375CC1D88951Q28592645-E3ACFFD0-BC34-4CE2-9E13-D2299D5D5B92Q28592742-71F77747-C335-42C6-8D6C-D44069ACF95DQ28593881-D1E3EB4E-ADC6-4382-9FA6-7C6C0A0EFE54
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
proteinë
@sq
proteïne in Pancreatic and duodenal homeobox 1
@nl
protèin
@ace
بروتين في فأر المنازل
@ar
name
Pancreatic and duodenal homeobox 1
@en
type
label
Pancreatic and duodenal homeobox 1
@en
altLabel
IDX-1
@en
IPF-1
@en
Insulin promoter factor 1
@en
Pdx1
@en
STF-1
@en
insulin promoter factor 1, homeodomain transcription factor
@en
islet/duodenum homeobox 1
@en
pancreas/duodenum homeobox protein 1
@en
pancreatic and duodenal homeobox gene 1
@en
somatostatin-transactivating factor 1
@en
prefLabel
Pancreatic and duodenal homeobox 1
@en
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ENSMUSP00000082729