about
P688
Patched1 interacts with cyclin B1 to regulate cell cycle progressionHaploinsufficiency of the forkhead gene Foxf1, a target for sonic hedgehog signaling, causes lung and foregut malformationsDissection of the mammalian midbody proteome reveals conserved cytokinesis mechanisms.Indian hedgehog mutations causing brachydactyly type A1 impair Hedgehog signal transduction at multiple levelsThe hedgehog receptor patched is involved in cholesterol transportWdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeletonC2cd3 is required for cilia formation and Hedgehog signaling in mouse.The whereabouts of a morphogen: direct evidence for short- and graded long-range activity of hedgehog signaling peptidesGrowth and pattern of the mammalian neural tube are governed by partially overlapping feedback activities of the hedgehog antagonists patched 1 and Hhip1Patched1 functions as a gatekeeper by promoting cell cycle progressionHepatic Hedgehog signaling contributes to the regulation of IGF1 and IGFBP1 serum levelsEpidermal hyperplasia and expansion of the interfollicular stem cell compartment in mutant mice with a C-terminal truncation of Patched1The primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiationA spontaneous mouse mutation, mesenchymal dysplasia (mes), is caused by a deletion of the most C-terminal cytoplasmic domain of patched (ptc)Sonic hedgehog protein signals not as a hydrolytic enzyme but as an apparent ligand for patchedCholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1Combined activities of hedgehog signaling inhibitors regulate pancreas developmentPatched 1 and patched 2 redundancy has a key role in regulating epidermal differentiationComplex interactions between genes controlling trafficking in primary ciliaGLI3 repressor controls nephron number via regulation of Wnt11 and Ret in ureteric tip cellsCilia and Hedgehog responsiveness in the mouseCilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conservedMissing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epitheliaAltered neural cell fates and medulloblastoma in mouse patched mutantsPrecocious cerebellum development and improved motor functions in mice lacking the astrocyte cilium-, patched 1-associated Gpr37l1 receptorRegulation of pancreas development by hedgehog signalingDisruption of Scube2 Impairs Endochondral Bone FormationInvolvement of Sonic hedgehog (Shh) in mouse embryonic lung growth and morphogenesisDefects in mouse mammary gland development caused by conditional haploinsufficiency of Patched-1Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R symmetry by the mouse nodePromotion of Hras-induced squamous carcinomas by a polymorphic variant of the Patched gene in FVB mice.Cellular Functions of the Autism Risk Factor PTCHD1 in Mice.
P921
Q24291186-F07D846A-FC88-4FB5-B0BB-366345D8A772Q24291542-8B3BCCB0-9E6D-461E-9F05-716A82D8FE78Q24294556-5C80BBBF-B8F2-4027-9D30-E6478AB22FA8Q24301248-77301D5F-945F-482E-9054-96744BEE426BQ24338297-5CAB90C1-B66D-4886-8198-83D36264B2EBQ27316402-96ECE9B2-E534-4985-A5CA-904842164207Q27967629-830D663B-EEDA-44D8-97FD-6C90B99AFA37Q28209351-F8A21740-AF72-4F75-B5BD-E83D22444675Q28296269-0257B557-49CE-4D36-94C2-D8E069B21115Q28298227-279EC021-7A8F-40EB-B981-13B49846756BQ28504728-8F7FB07C-81DA-486A-8C8F-7F2C6A1AE8C1Q28504970-091EB318-FE16-4A98-B750-5A3889CE86CAQ28507794-5B5C7FB2-FD1A-4737-B8BD-8E72F7CE4019Q28508239-5CE51989-EF03-4BCF-93EB-41529E4C7E78Q28508563-A564B3AE-4991-4E5C-9CD0-03D5BC1EDEF2Q28509262-A5C6D615-44F5-44B7-96FE-EC3C5B6C4933Q28510309-CB383A38-B8A2-40D8-A94C-0D0271E00007Q28511851-FD421387-EF10-47AB-B4CC-279FF2EAAB17Q28512423-940F4C3F-43FA-43D4-A3CC-BA163C20CA1AQ28513713-1463B172-D25B-45FE-94CB-72055CA78E2BQ28585101-F89FA042-0616-4D55-81AB-8A2342310FFEQ28585804-2E3FAD59-E99A-47E9-BDCD-D337A671A791Q28586598-C0E3E429-57C1-420C-8D75-0B4910DEEA5AQ28588056-ABC6DEF6-CF04-426E-9AD3-238D84A40DB0Q28590565-D55F1CC5-AB4A-4299-97CE-E728D316E1CDQ28591061-2A1CDDDC-5FB3-4508-96F5-ECD8F03C349FQ28591452-289C5CD3-8C94-4B4D-A717-1DEDB2888EB2Q28592724-FBF12656-3A95-450F-A147-B3BEAF77CDC6Q28593312-69DC8975-B1B8-493C-9177-D60EC98079F3Q28594387-53A31F97-64A4-4509-8979-5DBCADF6EBF8Q40182155-9FF92C3D-E953-4283-89B2-B4C308F2313EQ47423806-2E081BE9-61E4-4A20-B624-B34A9DA242D8
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
proteinë
@sq
proteïne in Patched 1
@nl
protèin
@ace
بروتين في فأر المنازل
@ar
name
Patched 1
@en
type
label
Patched 1
@en
altLabel
Ptch1 protein +12b
@en
Ptch1
@en
mesenchymal dysplasia
@en
patched homolog 1
@en
protein patched homolog 1
@en
prefLabel
Patched 1
@en
P680
P681
P682
P705
P352
P31
P352
P637
NP_001315443
P680
P681
P682
P702
P703
P705
ENSMUSP00000021921
ENSMUSP00000141298
ENSMUSP00000141309
ENSMUSP00000141489
ENSMUSP00000141766
ENSMUSP00000141990
ENSMUSP00000142036