Redox regulation of cell signaling by selenocysteine in mammalian thioredoxin reductases
about
New mammalian selenocysteine-containing proteins identified with an algorithm that searches for selenocysteine insertion sequence elementsCharacterization of Sptrx, a novel member of the thioredoxin family specifically expressed in human spermatozoaHow selenium has altered our understanding of the genetic codeStructure and mechanism of mammalian thioredoxin reductase: the active site is a redox-active selenolthiol/selenenylsulfide formed from the conserved cysteine-selenocysteine sequenceGenomic organisation and alternative splicing of mouse and human thioredoxin reductase 1 genesEffects of hexamethylene diisocyanate exposure on human airway epithelial cells: in vitro cellular and molecular studies.The redox biology of schistosome parasites and applications for drug developmentStructural Analysis of Glutaredoxin Domain of Mus musculus Thioredoxin Glutathione ReductaseCharacterization of selenoprotein P as a selenium supply proteinParadoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health ImplicationsGene expression changes for antioxidants pathways in the mouse cochlea: relations to age-related hearing deficits.Rapid induction of cell death by selenium-compromised thioredoxin reductase 1 but not by the fully active enzyme containing selenocysteineSelective targeting of selenocysteine in thioredoxin reductase by the half mustard 2-chloroethyl ethyl sulfide in lung epithelial cellsSelenoprotein oxidoreductase with specificity for thioredoxin and glutathione systemsInfluence of pH and flanking serine on the redox potential of S-S and S-Se bridges of Cys-Cys and Cys-Sec peptides.Selenium in chemistry and biochemistry in comparison to sulfur.The functional role of selenocysteine (Sec) in the catalysis mechanism of large thioredoxin reductases: proposition of a swapping catalytic triad including a Sec-His-Glu state.Thioredoxin and glutathione systems differ in parasitic and free-living platyhelminthsQuantitative loci regulating plasma levels of gamma glutamyl transferase and albumin and their genetic correlations with cardiovascular risk factors.CUG start codon generates thioredoxin/glutathione reductase isoforms in mouse testes.News and views on thioredoxin reductases.Selenium metabolism in zebrafish: multiplicity of selenoprotein genes and expression of a protein containing 17 selenocysteine residues.Selective inhibition of selenocysteine tRNA maturation and selenoprotein synthesis in transgenic mice expressing isopentenyladenosine-deficient selenocysteine tRNA.Thioredoxin reductase two modes of catalysis have evolved.Crystal structures of oxidized and reduced mitochondrial thioredoxin reductase provide molecular details of the reaction mechanism.Selenoproteins and selenocysteine insertion system in the model plant cell system, Chlamydomonas reinhardtiiMethaneseleninic acid is a substrate for truncated mammalian thioredoxin reductase: implications for the catalytic mechanism and redox signalingTrends in selenium biochemistry.Genetic variation in selenoprotein genes, lifestyle, and risk of colon and rectal cancer.Molecular pharmacology and antitumor activity of palmarumycin-based inhibitors of thioredoxin reductase.Free radical theory of autoimmunitySelective removal of the selenocysteine tRNA [Ser]Sec gene (Trsp) in mouse mammary epithelium.Mammalian thioredoxin reductase: oxidation of the C-terminal cysteine/selenocysteine active site forms a thioselenide, and replacement of selenium with sulfur markedly reduces catalytic activity.Protein kinase-regulated expression and immune function of thioredoxin reductase 1 in mouse macrophages.Susceptibility of the antioxidant selenoenyzmes thioredoxin reductase and glutathione peroxidase to alkylation-mediated inhibition by anticancer acylfulvenesThe conserved Trp114 residue of thioredoxin reductase 1 has a redox sensor-like function triggering oligomerization and crosslinking upon oxidative stress related to cell deathSparing effects of selenium and ascorbic acid on vitamin C and E in guinea pig tissuesA recoding element that stimulates decoding of UGA codons by Sec tRNA[Ser]SecSelenoproteins and their impact on human health through diverse physiological pathways.Resistance training and redox homeostasis: Correlation with age-associated genomic changes
P2860
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P2860
Redox regulation of cell signaling by selenocysteine in mammalian thioredoxin reductases
description
1999 nî lūn-bûn
@nan
1999 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Redox regulation of cell signaling by selenocysteine in mammalian thioredoxin reductases
@ast
Redox regulation of cell signaling by selenocysteine in mammalian thioredoxin reductases
@en
Redox regulation of cell signaling by selenocysteine in mammalian thioredoxin reductases
@en-gb
Redox regulation of cell signaling by selenocysteine in mammalian thioredoxin reductases
@nl
type
label
Redox regulation of cell signaling by selenocysteine in mammalian thioredoxin reductases
@ast
Redox regulation of cell signaling by selenocysteine in mammalian thioredoxin reductases
@en
Redox regulation of cell signaling by selenocysteine in mammalian thioredoxin reductases
@en-gb
Redox regulation of cell signaling by selenocysteine in mammalian thioredoxin reductases
@nl
prefLabel
Redox regulation of cell signaling by selenocysteine in mammalian thioredoxin reductases
@ast
Redox regulation of cell signaling by selenocysteine in mammalian thioredoxin reductases
@en
Redox regulation of cell signaling by selenocysteine in mammalian thioredoxin reductases
@en-gb
Redox regulation of cell signaling by selenocysteine in mammalian thioredoxin reductases
@nl
P2093
P2860
P921
P3181
P356
P1476
Redox regulation of cell signaling by selenocysteine in mammalian thioredoxin reductases
@en
P2093
P2860
P304
P3181
P356
10.1074/JBC.274.35.24522
P407
P577
1999-08-27T00:00:00Z