Human thioredoxin reductase from HeLa cells: selective alkylation of selenocysteine in the protein inhibits enzyme activity and reduction with NADPH influences affinity to heparin
about
Redox regulation of cell signaling by selenocysteine in mammalian thioredoxin reductasesHuman mitochondrial thioredoxin reductase cDNA cloning, expression and genomic organizationThioredoxin reductaseEssential role for mitochondrial thioredoxin reductase in hematopoiesis, heart development, and heart functionStructure and mechanism of mammalian thioredoxin reductase: the active site is a redox-active selenolthiol/selenenylsulfide formed from the conserved cysteine-selenocysteine sequenceTrxR1 as a potent regulator of the Nrf2-Keap1 response systemProteome changes in human bronchoalveolar cells following styrene exposure indicate involvement of oxidative stress in the molecular-response mechanismCytoplasmic thioredoxin reductase is essential for embryogenesis but dispensable for cardiac developmentMolecular cloning and characterization of a mitochondrial selenocysteine-containing thioredoxin reductase from rat liverThe functional role of selenocysteine (Sec) in the catalysis mechanism of large thioredoxin reductases: proposition of a swapping catalytic triad including a Sec-His-Glu state.The efficiency of Escherichia coli selenocysteine insertion is influenced by the immediate downstream nucleotide.News and views on thioredoxin reductases.Thioredoxin reductase two modes of catalysis have evolved.Methaneseleninic acid is a substrate for truncated mammalian thioredoxin reductase: implications for the catalytic mechanism and redox signalingLevels of major selenoproteins in T cells decrease during HIV infection and low molecular mass selenium compounds increase.Mammalian thioredoxin reductase: oxidation of the C-terminal cysteine/selenocysteine active site forms a thioselenide, and replacement of selenium with sulfur markedly reduces catalytic activity.Molecular modeling and in vitro activity of an HIV-1-encoded glutathione peroxidaseAugmented S-nitrosylation contributes to impaired relaxation in angiotensin II hypertensive mouse aorta: role of thioredoxin reductase.Developments and recent advancements in the field of endogenous amino acid selective bond forming reactions for bioconjugation.Heterogeneity within animal thioredoxin reductases. Evidence for alternative first exon splicing.Regulation of human thioredoxin reductase expression and activity by 3'-untranslated region selenocysteine insertion sequence and mRNA instability elements.Traceless ligation of cysteine peptides using selective deselenization.Oxidation of thioredoxin reductase in HeLa cells stimulated with tumor necrosis factor-alpha.NAD(H) enhances the Cu(II)-mediated inactivation of lactate dehydrogenase by increasing the accessibility of sulfhydryl groups.Alpha-selenoconotoxins, a new class of potent alpha7 neuronal nicotinic receptor antagonists.A gold mine of fascinating enzymes: those remarkable, strictly anaerobic bacteria, Methanococcus vannielii and Clostridium sticklandii.The role of electrostatics in TrxR electron transfer mechanism: A computational approach.
P2860
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P2860
Human thioredoxin reductase from HeLa cells: selective alkylation of selenocysteine in the protein inhibits enzyme activity and reduction with NADPH influences affinity to heparin
description
1998 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 1998
@ast
im Juli 1998 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1998/07/21)
@sk
vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd op 1998/07/21)
@nl
наукова стаття, опублікована в липні 1998
@uk
name
Human thioredoxin reductase fr ...... influences affinity to heparin
@ast
Human thioredoxin reductase fr ...... influences affinity to heparin
@en
Human thioredoxin reductase fr ...... influences affinity to heparin
@nl
type
label
Human thioredoxin reductase fr ...... influences affinity to heparin
@ast
Human thioredoxin reductase fr ...... influences affinity to heparin
@en
Human thioredoxin reductase fr ...... influences affinity to heparin
@nl
prefLabel
Human thioredoxin reductase fr ...... influences affinity to heparin
@ast
Human thioredoxin reductase fr ...... influences affinity to heparin
@en
Human thioredoxin reductase fr ...... influences affinity to heparin
@nl
P2860
P356
P1476
Human thioredoxin reductase fr ...... influences affinity to heparin
@en
P2093
S. N. Gorlatov
T. C. Stadtman
P2860
P304
P356
10.1073/PNAS.95.15.8520
P407
P577
1998-07-21T00:00:00Z