The topoisomerase-related function gene TRF4 affects cellular sensitivity to the antitumor agent camptothecin
about
A new yeast poly(A) polymerase complex involved in RNA quality controlDNA replication meets genetic exchange: chromosomal damage and its repair by homologous recombinationIntrinsic 5'-deoxyribose-5-phosphate lyase activity in Saccharomyces cerevisiae Trf4 protein with a possible role in base excision DNA repairRNA-specific ribonucleotidyl transferasesSaccharomyces cerevisiae DNA polymerase epsilon and polymerase sigma interact physically and functionally, suggesting a role for polymerase epsilon in sister chromatid cohesionThe cohesin complex: sequence homologies, interaction networks and shared motifsTrf4 and Trf5 proteins of Saccharomyces cerevisiae exhibit poly(A) RNA polymerase activity but no DNA polymerase activity.Contribution of Trf4/5 and the nuclear exosome to genome stability through regulation of histone mRNA levels in Saccharomyces cerevisiae.Nucleocytoplasmic distribution of budding yeast protein kinase A regulatory subunit Bcy1 requires Zds1 and is regulated by Yak1-dependent phosphorylation of its targeting domainNuclear surveillance and degradation of hypomodified initiator tRNAMet in S. cerevisiaeTrf4 targets ncRNAs from telomeric and rDNA spacer regions and functions in rDNA copy number control.Qri2/Nse4, a component of the essential Smc5/6 DNA repair complex.Determination of the 'critical region' for cat-like cry of Cri-du-chat syndrome and analysis of candidate genes by quantitative PCRStructure/function analysis of the Saccharomyces cerevisiae Trf4/Pol sigma DNA polymerase.Evidence that replication fork components catalyze establishment of cohesion between sister chromatids.Structural maintenance of chromosomes (SMC) proteins: conserved molecular properties for multiple biological functions.mcl1+, the Schizosaccharomyces pombe homologue of CTF4, is important for chromosome replication, cohesion, and segregation.Cytoplasmic poly(A) polymerases mediate cellular responses to S phase arrestAir1 zinc knuckles 4 and 5 and a conserved IWRXY motif are critical for the function and integrity of the Trf4/5-Air1/2-Mtr4 polyadenylation (TRAMP) RNA quality control complex.Inference of tumor phylogenies from genomic assays on heterogeneous samples.Repair of topoisomerase I-mediated DNA damage.Nuclear RNA surveillance: role of TRAMP in controlling exosome specificity.TRF4 is involved in polyadenylation of snRNAs in Drosophila melanogaster.Histone tail-independent chromatin binding activity of recombinant cohesin holocomplex.Modulation of the structure, catalytic activity, and fidelity of African swine fever virus DNA polymerase X by a reversible disulfide switch.Therapeutic intervention by the simultaneous inhibition of DNA repair and type I or type II DNA topoisomerases: one strategy, many outcomes.Yeast nuclear RNA processing.Active site mutations in DNA topoisomerase I distinguish the cytotoxic activities of camptothecin and the indolocarbazole, rebeccamycin.Fission yeast Cid12 has dual functions in chromosome segregation and checkpoint control.zds1, a novel gene encoding an ortholog of Zds1 and Zds2, controls sexual differentiation, cell wall integrity and cell morphology in fission yeast.Pathways for repair of topoisomerase I covalent complexes in Saccharomyces cerevisiae.The deubiquitinating enzyme Doa4p protects cells from DNA topoisomerase I poisons.
P2860
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P2860
The topoisomerase-related function gene TRF4 affects cellular sensitivity to the antitumor agent camptothecin
description
1999 nî lūn-bûn
@nan
1999 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մարտին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
The topoisomerase-related func ...... e antitumor agent camptothecin
@ast
The topoisomerase-related func ...... e antitumor agent camptothecin
@en
The topoisomerase-related func ...... e antitumor agent camptothecin
@en-gb
The topoisomerase-related func ...... e antitumor agent camptothecin
@nl
type
label
The topoisomerase-related func ...... e antitumor agent camptothecin
@ast
The topoisomerase-related func ...... e antitumor agent camptothecin
@en
The topoisomerase-related func ...... e antitumor agent camptothecin
@en-gb
The topoisomerase-related func ...... e antitumor agent camptothecin
@nl
prefLabel
The topoisomerase-related func ...... e antitumor agent camptothecin
@ast
The topoisomerase-related func ...... e antitumor agent camptothecin
@en
The topoisomerase-related func ...... e antitumor agent camptothecin
@en-gb
The topoisomerase-related func ...... e antitumor agent camptothecin
@nl
P2093
P2860
P356
P1476
The topoisomerase-related func ...... e antitumor agent camptothecin
@en
P2093
C Walowsky
D J Fitzhugh
I B Castaño
M F Christman
P2860
P304
P356
10.1074/JBC.274.11.7302
P407
P577
1999-03-12T00:00:00Z