Air1 zinc knuckles 4 and 5 and a conserved IWRXY motif are critical for the function and integrity of the Trf4/5-Air1/2-Mtr4 polyadenylation (TRAMP) RNA quality control complex.
about
Air2p is critical for the assembly and RNA-binding of the TRAMP complex and the KOW domain of Mtr4p is crucial for exosome activationThreading the barrel of the RNA exosomeSki2-like RNA helicase structures: common themes and complex assembliesRibonucleoprotein complexes that control circadian clocksNuclear noncoding RNA surveillance: is the end in sight?Efficient mRNA polyadenylation requires a ubiquitin-like domain, a zinc knuckle, and a RING finger domain, all contained in the Mpe1 protein.Mutations in Mtr4 Structural Domains Reveal Their Important Role in Regulating tRNAiMet Turnover in Saccharomyces cerevisiae and Mtr4p Enzymatic Activities In Vitro.Certain adenylated non-coding RNAs, including 5' leader sequences of primary microRNA transcripts, accumulate in mouse cells following depletion of the RNA helicase MTR4Comparison of the yeast and human nuclear exosome complexes.Nab3 facilitates the function of the TRAMP complex in RNA processing via recruitment of Rrp6 independent of Nrd1Defective structural RNA processing in relapsing-remitting multiple sclerosisAir proteins control differential TRAMP substrate specificity for nuclear RNA surveillanceNuclear RNA surveillance: role of TRAMP in controlling exosome specificity.Exosomal Protein Deficiencies: How Abnormal RNA Metabolism Results in Childhood-Onset Neurological DiseasesTranscript-RNA-templated DNA recombination and repairA conserved virus-induced cytoplasmic TRAMP-like complex recruits the exosome to target viral RNA for degradation.Cotranscriptional recruitment of yeast TRAMP complex to intronic sequences promotes optimal pre-mRNA splicing.Attacked from All Sides: RNA Decay in Antiviral Defense.HTLV-1 Rex: the courier of viral messages making use of the host vehicle.Human Tra2 proteins jointly control a CHEK1 splicing switch among alternative and constitutive target exons.RNA Exosome and Non-coding RNA-Coupled Mechanisms in AID-Mediated Genomic Alterations.Structure of the RBM7-ZCCHC8 core of the NEXT complex reveals connections to splicing factors.Interaction between the RNA-dependent ATPase and poly(A) polymerase subunits of the TRAMP complex is mediated by short peptides and important for snoRNA processing.The RNA exosome and RNA exosome-linked disease.Targeting the nuclear RNA exosome: Poly(A) binding proteins enter the stage.RNA surveillance by the nuclear RNA exosome: mechanisms and significance.Diminished nuclear RNA decay upon infection upregulates antibacterial noncoding RNAsThe splicing factor SRSF3 is functionally connected to the nuclear RNA exosome for intronless mRNA decay
P2860
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P2860
Air1 zinc knuckles 4 and 5 and a conserved IWRXY motif are critical for the function and integrity of the Trf4/5-Air1/2-Mtr4 polyadenylation (TRAMP) RNA quality control complex.
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Air1 zinc knuckles 4 and 5 and ...... ) RNA quality control complex.
@ast
Air1 zinc knuckles 4 and 5 and ...... ) RNA quality control complex.
@en
type
label
Air1 zinc knuckles 4 and 5 and ...... ) RNA quality control complex.
@ast
Air1 zinc knuckles 4 and 5 and ...... ) RNA quality control complex.
@en
prefLabel
Air1 zinc knuckles 4 and 5 and ...... ) RNA quality control complex.
@ast
Air1 zinc knuckles 4 and 5 and ...... ) RNA quality control complex.
@en
P2093
P2860
P356
P1476
Air1 zinc knuckles 4 and 5 and ...... ) RNA quality control complex.
@en
P2093
Anita H Corbett
Ayan Banerjee
Elizabeth A Bowman
Emily H Rubinson
Maja O Kodani
Max E Rubinson
Meghan K Purohit
Milo B Fasken
Ramiro Chavez
Sara W Leung
P2860
P304
37429-37445
P356
10.1074/JBC.M111.271494
P407
P577
2011-08-30T00:00:00Z