RAE1 is a shuttling mRNA export factor that binds to a GLEBS-like NUP98 motif at the nuclear pore complex through multiple domains
about
TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architectureCalreticulin Is a receptor for nuclear export.Novel vertebrate nucleoporins Nup133 and Nup160 play a role in mRNA export.The entire Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosisNucleocytoplasmic transport of proteins and poly(A)+ RNA in reconstituted Tpr-less nuclei in living mammalian cellsHerpes simplex virus ICP27 protein directly interacts with the nuclear pore complex through Nup62, inhibiting host nucleocytoplasmic transport pathwaysRAE-1, a novel PHR binding protein, is required for axon termination and synapse formation in Caenorhabditis elegansStable kinetochore-microtubule interactions depend on the Ska complex and its new component Ska3/C13Orf3.A microtubule-associated zinc finger protein, BuGZ, regulates mitotic chromosome alignment by ensuring Bub3 stability and kinetochore targetingBuGZ is required for Bub3 stability, Bub1 kinetochore function, and chromosome alignmentInteraction between the shuttling mRNA export factor Gle1 and the nucleoporin hCG1: a conserved mechanism in the export of Hsp70 mRNA.The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substratesThe Ct-RAE1 protein interacts with Balbiani ring RNP particles at the nuclear pore.Nup98 localizes to both nuclear and cytoplasmic sides of the nuclear pore and binds to two distinct nucleoporin subcomplexesMex67p of Schizosaccharomyces pombe interacts with Rae1p in mediating mRNA exportDisruption of the FG nucleoporin NUP98 causes selective changes in nuclear pore complex stoichiometry and functionCofactor requirements for nuclear export of Rev response element (RRE)- and constitutive transport element (CTE)-containing retroviral RNAs. An unexpected role for actin.An essential role for hGle1 nucleocytoplasmic shuttling in mRNA export.Rae1 interaction with NuMA is required for bipolar spindle formationThe RanGTP Pathway: From Nucleo-Cytoplasmic Transport to Spindle Assembly and BeyondComplex Commingling: Nucleoporins and the Spindle Assembly CheckpointStructural and functional analysis of the interaction between the nucleoporin Nup98 and the mRNA export factor Rae1Molecular Basis for the Anchoring of Proto-Oncoprotein Nup98 to the Cytoplasmic Face of the Nuclear Pore ComplexBinding of the Mex67p/Mtr2p heterodimer to FXFG, GLFG, and FG repeat nucleoporins is essential for nuclear mRNA export.Elf1p, a member of the ABC class of ATPases, functions as a mRNA export factor in Schizosacchromyces pombe.An essential nuclear envelope integral membrane protein, Brr6p, required for nuclear transportThe yeast hnRNP-Like proteins Yra1p and Yra2p participate in mRNA export through interaction with Mex67p.The nucleoporin Nup98 is a site for GDP/GTP exchange on ran and termination of karyopherin beta 2-mediated nuclear importThe mitotic checkpoint protein hBUB3 and the mRNA export factor hRAE1 interact with GLE2p-binding sequence (GLEBS)-containing proteinsU2AF participates in the binding of TAP (NXF1) to mRNAIn vitro analysis of nuclear transport mediated by the C-terminal shuttle domain of TapThe role of NUP98 gene fusions in hematologic malignancyNUP98 dysregulation in myeloid leukemogenesisREF, an evolutionary conserved family of hnRNP-like proteins, interacts with TAP/Mex67p and participates in mRNA nuclear export.Human Nup98 regulates the localization and activity of DExH/D-box helicase DHX9Nup98 is a mobile nucleoporin with transcription-dependent dynamics.Early aging-associated phenotypes in Bub3/Rae1 haploinsufficient mice.Intranuclear dynamics of the Nup107-160 complex.The cellular DExD/H-box RNA-helicases UAP56 and URH49 exhibit a CRM1-independent nucleocytoplasmic shuttling activity.Dissection of the transformation of primary human hematopoietic cells by the oncogene NUP98-HOXA9
P2860
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P2860
RAE1 is a shuttling mRNA export factor that binds to a GLEBS-like NUP98 motif at the nuclear pore complex through multiple domains
description
1999 nî lūn-bûn
@nan
1999 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
RAE1 is a shuttling mRNA expor ...... mplex through multiple domains
@ast
RAE1 is a shuttling mRNA expor ...... mplex through multiple domains
@en
RAE1 is a shuttling mRNA expor ...... mplex through multiple domains
@en-gb
RAE1 is a shuttling mRNA expor ...... mplex through multiple domains
@nl
type
label
RAE1 is a shuttling mRNA expor ...... mplex through multiple domains
@ast
RAE1 is a shuttling mRNA expor ...... mplex through multiple domains
@en
RAE1 is a shuttling mRNA expor ...... mplex through multiple domains
@en-gb
RAE1 is a shuttling mRNA expor ...... mplex through multiple domains
@nl
prefLabel
RAE1 is a shuttling mRNA expor ...... mplex through multiple domains
@ast
RAE1 is a shuttling mRNA expor ...... mplex through multiple domains
@en
RAE1 is a shuttling mRNA expor ...... mplex through multiple domains
@en-gb
RAE1 is a shuttling mRNA expor ...... mplex through multiple domains
@nl
P2093
P2860
P356
P1476
RAE1 is a shuttling mRNA expor ...... mplex through multiple domains
@en
P2093
C E Pritchard
J M van Deursen
L H Kasper
M Fornerod
P2860
P304
P356
10.1083/JCB.145.2.237
P407
P577
1999-04-19T00:00:00Z