about
The LIM domain protein LMO4 interacts with the cofactor CtIP and the tumor suppressor BRCA1 and inhibits BRCA1 activityOverexpression of LMO4 induces mammary hyperplasia, promotes cell invasion, and is a predictor of poor outcome in breast cancerStructural basis for the recognition of ldb1 by the N-terminal LIM domains of LMO2 and LMO4Null mutation of the Lmo4 gene or a combined null mutation of the Lmo1/Lmo3 genes causes perinatal lethality, and Lmo4 controls neural tube development in miceDefective neural tube closure and anteroposterior patterning in mice lacking the LIM protein LMO4 or its interacting partner Deaf-1The LIM domain gene LMO4 inhibits differentiation of mammary epithelial cells in vitro and is overexpressed in breast cancer.Modulation of the interleukin-6 receptor subunit glycoprotein 130 complex and its signaling by LMO4 interaction.sIL-6R: more than an agonist?LIM only 4 is overexpressed in late stage pancreas cancerLIM-domain-only proteins in cancer.LIM-domain-only proteins: multifunctional nuclear transcription coregulators that interacts with diverse proteins.E2F-HDAC complexes negatively regulate the tumor suppressor gene ARHI in breast cancer.Repression of Lim only protein 4-activated transcription inhibits proliferation and induces apoptosis of normal mammary epithelial cells and breast cancer cells.Impact of the chemotherapy cocktail used to treat testicular cancer on the gene expression profile of germ cells from male Brown-Norway rats.Tandem LIM domains provide synergistic binding in the LMO4:Ldb1 complex.The LIM domain protein Lmo4 is highly expressed in proliferating mouse epithelial tissues.Differential expression of LMO4 protein in Alzheimer's disease.Loss of the LIM domain protein Lmo4 in the mammary gland during pregnancy impedes lobuloalveolar development.
P2860
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P2860
description
1999 nî lūn-bûn
@nan
1999 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Molecular cloning of LMO41, a new human LIM domain gene
@ast
Molecular cloning of LMO41, a new human LIM domain gene
@en
Molecular cloning of LMO41, a new human LIM domain gene
@en-gb
Molecular cloning of LMO41, a new human LIM domain gene
@nl
type
label
Molecular cloning of LMO41, a new human LIM domain gene
@ast
Molecular cloning of LMO41, a new human LIM domain gene
@en
Molecular cloning of LMO41, a new human LIM domain gene
@en-gb
Molecular cloning of LMO41, a new human LIM domain gene
@nl
prefLabel
Molecular cloning of LMO41, a new human LIM domain gene
@ast
Molecular cloning of LMO41, a new human LIM domain gene
@en
Molecular cloning of LMO41, a new human LIM domain gene
@en-gb
Molecular cloning of LMO41, a new human LIM domain gene
@nl
P2093
P1476
Molecular cloning of LMO41, a new human LIM domain gene
@en
P2093
P304
P356
10.1016/S0167-4781(99)00037-8
P407
P577
1999-04-14T00:00:00Z