Fibroblast growth factor receptor-1-mediated endothelial cell proliferation is dependent on the Src homology (SH) 2/SH3 domain-containing adaptor protein Crk - Test2 - elhamkhani - TriplyDB

Fibroblast growth factor receptor-1-mediated endothelial cell proliferation is dependent on the Src homology (SH) 2/SH3 domain-containing adaptor protein Crk

Fibroblast growth factor receptor-1-mediated endothelial cell proliferation is dependent on the Src homology (SH) 2/SH3 domain-containing adaptor protein Crk

http://www.wikidata.org/entity/Q22010490

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The Shb adaptor protein binds to tyrosine 766 in the FGFR-1 and regulates the Ras/MEK/MAPK pathway via FRS2 phosphorylation in endothelial cells Rap1a is a key regulator of fibroblast growth factor 2-induced angiogenesis and together with Rap1b controls human endothelial cell functions Impaired FGF signaling contributes to cleft lip and palate Functional roles of fibroblast growth factor receptors (FGFRs) signaling in human cancers Genetic insights into the mechanisms of Fgf signaling Fibroblast growth factor signaling in Caenorhabditis elegans Src activation plays an important key role in lymphomagenesis induced by FGFR1 fusion kinases Fgf8 expression in the Tbx1 domain causes skeletal abnormalities and modifies the aortic arch but not the outflow tract phenotype of Tbx1 mutants FRS2 via fibroblast growth factor receptor 1 is required for platelet-derived growth factor receptor beta-mediated regulation of vascular smooth muscle marker gene expression Signalling to actin: role of C3G, a multitasking guanine-nucleotide-exchange factor.Reduced tumor growth in vivo and increased c-Abl activity in PC3 prostate cancer cells overexpressing the Shb adapter protein.Frs2α and Shp2 signal independently of Gab to mediate FGF signaling in lens development.Low-molecular-weight protein tyrosine phosphatase is a positive component of the fibroblast growth factor receptor signaling pathway.The Fibroblast Growth Factor signaling pathway Crkl deficiency disrupts Fgf8 signaling in a mouse model of 22q11 deletion syndromes.Fibronectin induces endothelial cell migration through β1 integrin and Src-dependent phosphorylation of fibroblast growth factor receptor-1 at tyrosines 653/654 and 766.Fgfr1 regulates development through the combinatorial use of signaling proteins.Phosphorylation of serine 779 in fibroblast growth factor receptor 1 and 2 by protein kinase C(epsilon) regulates Ras/mitogen-activated protein kinase signaling and neuronal differentiation.Fibroblast growth factors, old kids on the new block.Structural and functional basis of a role for CRKL in a fibroblast growth factor 8-induced feed-forward loop.FGFR1-Frs2/3 signalling maintains sensory progenitors during inner ear hair cell formation.FGFs: Neurodevelopment's Jack-of-all-Trades - How Do They Do it?Frs2alpha-deficiency in cardiac progenitors disrupts a subset of FGF signals required for outflow tract morphogenesis.Fibroblast growth factor receptor 2 phosphorylation on serine 779 couples to 14-3-3 and regulates cell survival and proliferation.Regulation of skeletal muscle stem cells by fibroblast growth factors.Functional characterization of a novel FGFR2 mutation, E731K, in craniosynostosis.The nonreceptor protein-tyrosine kinase c-Fes is involved in fibroblast growth factor-2-induced chemotaxis of murine brain capillary endothelial cells.Fibroblast growth factor receptor-1 phosphorylation requirement for cardiomyocyte differentiation in murine embryonic stem cells.p120 Ras GTPase-activating protein associates with fibroblast growth factor receptors in Drosophila.Hippocampal granule neuron production and population size are regulated by levels of bFGF.Roles of extracellular signal-regulated kinase and Akt signaling in coordinating nuclear transcription factor-kappaB-dependent cell survival after serotonin 1A receptor activation.The mammalian target of rapamycin-p70 ribosomal S6 kinase but not phosphatidylinositol 3-kinase-Akt signaling is responsible for fibroblast growth factor-9-induced cell proliferation.A novel fibroblast growth factor-1 ligand with reduced heparin binding protects the heart against ischemia-reperfusion injury in the presence of heparin co-administration.Uncoupling the Mitogenic and Metabolic Functions of FGF1 by Tuning FGF1-FGF Receptor Dimer Stability.Crk proteins transduce FGF signaling to promote lens fiber cell elongation.MAPK and PI3K Signaling: at the Crossroads of Neural Crest Development.Docking protein SNT1 is a critical mediator of fibroblast growth factor signaling during Xenopus embryonic development.Amplification of FGFR1 gene and expression of FGFR1 protein is found in different histological types of lung carcinoma.

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Fibroblast growth factor receptor-1-mediated endothelial cell proliferation is dependent on the Src homology (SH) 2/SH3 domain-containing adaptor protein Crk

http://www.wikidata.org/entity/Q22010490

description

1999 nî lūn-bûn

@nan

1999 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

1999 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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1999年の論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年论文

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name

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Fibroblast growth factor recep ...... containing adaptor protein Crk

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JBC.274.36.25726

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Journal of Biological Chemistry

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E Landgren

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H Larsson

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P2860

cDNA cloning and expression of a human platelet-derived growth factor (PDGF) receptor specific for B-chain-containing PDGF molecules

C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins

Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction

Molecular cloning of a novel cytokine cDNA encoding the ninth member of the fibroblast growth factor family, which has a unique secretion property

FGF-18, a novel member of the fibroblast growth factor family, stimulates hepatic and intestinal proliferation.

Human mitogen-activated protein kinase kinase 7 (MKK7) is a highly conserved c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) activated by environmental stresses and physiological stimuli

Identification of Tyr-762 in the platelet-derived growth factor alpha-receptor as the binding site for Crk proteins

A ras-related gene with transformation suppressor activity

The SH2 and SH3 domain-containing Nck protein is oncogenic and a common target for phosphorylation by different surface receptors

CRK protein binds to two guanine nucleotide-releasing proteins for the Ras family and modulates nerve growth factor-induced activation of Ras in PC12 cells

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25726-34

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scholarly article

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10.1074/JBC.274.36.25726

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36

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274

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10464310

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