Rap1a is a key regulator of fibroblast growth factor 2-induced angiogenesis and together with Rap1b controls human endothelial cell functions - Test2 - elhamkhani - TriplyDB

Rap1a is a key regulator of fibroblast growth factor 2-induced angiogenesis and together with Rap1b controls human endothelial cell functions

Rap1a is a key regulator of fibroblast growth factor 2-induced angiogenesis and together with Rap1b controls human endothelial cell functions

http://www.wikidata.org/entity/Q24646480

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Unlocking the transcriptomes of two carcinogenic parasites, Clonorchis sinensis and Opisthorchis viverrini Small G proteins in the cardiovascular system: physiological and pathological aspects Rap1 GTPases: an emerging role in the cardiovasculature Cyclic AMP-Rap1A signaling activates RhoA to induce α(2c)-adrenoceptor translocation to the cell surface of microvascular smooth muscle cells Rap1b in smooth muscle and endothelium is required for maintenance of vascular tone and normal blood pressure.Recent insights into cerebral cavernous malformations: a complex jigsaw puzzle under construction.Novel pegylated interferon-β as strong suppressor of the malignant ascites in a peritoneal metastasis model of human cancer.The Ras-related protein, Rap1A, mediates thrombin-stimulated, integrin-dependent glioblastoma cell proliferation and tumor growth Effects of PEMF on microcirculation and angiogenesis in a model of acute hindlimb ischemia in diabetic rats.A novel interplay between Rap1 and PKA regulates induction of angiogenesis in prostate cancer.PI3-kinase γ promotes Rap1a-mediated activation of myeloid cell integrin α4β1, leading to tumor inflammation and growth Role of the cytoskeleton in formation and maintenance of angiogenic sprouts Rap1 GTPase activation and barrier enhancement in rpe inhibits choroidal neovascularization in vivo.Junctional adhesion molecule A promotes epithelial tight junction assembly to augment lung barrier function Rap1 promotes VEGFR2 activation and angiogenesis by a mechanism involving integrin αvβ₃.Prostacyclin post-treatment improves LPS-induced acute lung injury and endothelial barrier recovery via Rap1.PGE2 promotes angiogenesis through EP4 and PKA Cγ pathway.Breast cancer cell migration is regulated through junctional adhesion molecule-A-mediated activation of Rap1 GTPase.Rap1 promotes endothelial mechanosensing complex formation, NO release and normal endothelial function.Translational analysis of mouse and human placental protein and mRNA reveals distinct molecular pathologies in human preeclampsia.Angiogenic sprouting requires the fine tuning of endothelial cell cohesion by the Raf-1/Rok-α complex Small GTPase Rap1 Is Essential for Mouse Development and Formation of Functional Vasculature.Breaking barriers: insight into the pathogenesis of neovascular age-related macular degeneration.Rasip1 regulates vertebrate vascular endothelial junction stability through Epac1-Rap1 signaling.A novel interplay between Epac/Rap1 and mitogen-activated protein kinase kinase 5/extracellular signal-regulated kinase 5 (MEK5/ERK5) regulates thrombospondin to control angiogenesis.C3G knock-down enhances migration and invasion by increasing Rap1-mediated p38α activation, while it impairs tumor growth through p38α-independent mechanisms.Signal transduction pathways in chronic inflammatory autoimmune disease: small GTPases.Distinct functions for Rap1 signaling in vascular morphogenesis and dysfunction.Molecular mechanisms of AGE/RAGE-mediated fibrosis in the diabetic heart.Identification of key pathways and genes influencing prognosis in bladder urothelial carcinoma Gene expression profile of osseointegration of a hydrophilic compared with a hydrophobic microrough implant surface.Purinergic A2b Receptor Activation by Extracellular Cues Affects Positioning of the Centrosome and Nucleus and Causes Reduced Cell Migration.Role of FGF10 on tumorigenesis by MS-K.Rap1 in endothelial biology.Enhanced proliferation and migration of vascular smooth muscle cells in response to vascular injury under hyperglycemic conditions is controlled by beta3 integrin signaling.Rap1 signaling in endothelial barrier control.Regulation of vascular endothelial junction stability and remodeling through Rap1-Rasip1 signaling Kv7 Channel Activation Underpins EPAC-Dependent Relaxations of Rat Arteries.Isoform-specific differences between Rap1A and Rap1B GTPases in the formation of endothelial cell junctions.Region and cell-type resolved quantitative proteomic map of the human heart.

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Rap1a is a key regulator of fibroblast growth factor 2-induced angiogenesis and together with Rap1b controls human endothelial cell functions

http://www.wikidata.org/entity/Q24646480

description

2008 nî lūn-bûn

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2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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Molecular and Cellular Biology

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Rap1a is a key regulator of fi ...... man endothelial cell functions

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P2093

David A Ingram

http://www.w3.org/2001/XMLSchema#string

Fang Li

http://www.w3.org/2001/XMLSchema#string

Jingliang Yan

http://www.w3.org/2001/XMLSchema#string

Lawrence A Quilliam

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P2860

Fibroblast growth factor receptor-1-mediated endothelial cell proliferation is dependent on the Src homology (SH) 2/SH3 domain-containing adaptor protein Crk

RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1

A tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1

Local activation of Rap1 contributes to directional vascular endothelial cell migration accompanied by extension of microtubules on which RAPL, a Rap1-associating molecule, localizes

A ras-related gene with transformation suppressor activity

The Shb adaptor protein binds to tyrosine 766 in the FGFR-1 and regulates the Ras/MEK/MAPK pathway via FRS2 phosphorylation in endothelial cells

A vascular gene trap screen defines RasGRP3 as an angiogenesis-regulated gene required for the endothelial response to phorbol esters

RIAM, an Ena/VASP and Profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion

GEFs and GAPs: critical elements in the control of small G proteins

Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis

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5803-10

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scholarly article

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4790123

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10.1128/MCB.00393-08

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18

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28

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2008-09-01T00:00:00Z

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5226098

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18625726

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2546931

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