Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis
about
Selective translational repression of truncated proteins from frameshift mutation-derived mRNAs in tumorsMSH3 mismatch repair protein regulates sensitivity to cytotoxic drugs and a histone deacetylase inhibitor in human colon carcinoma cellsMatrix-assisted laser desorption/ionisation, time-of-flight mass spectrometry in genomics researchCurrent hypotheses on how microsatellite instability leads to enhanced survival of Lynch Syndrome patientsEpigenetic silencing of AXIN2 in colorectal carcinoma with microsatellite instabilityN-methyl-N'-nitro-N-nitrosoguanidine-induced senescence-like growth arrest in colon cancer cells is associated with loss of adenomatous polyposis coli protein, microtubule organization, and telomeric DNAHereditary nonpolyposis colorectal cancer in 95 families: differences and similarities between mutation-positive and mutation-negative kindredsMultiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiaeInteraction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatinSpontaneous tumorigenesis in mice defective in the MTH1 gene encoding 8-oxo-dGTPaseSimple tandem DNA repeats and human genetic diseaseEra of universal testing of microsatellite instability in colorectal cancerPromoter methylation status of hMLH1, MGMT, and CDKN2A/p16 in colorectal adenomasReview of the Lynch syndrome: history, molecular genetics, screening, differential diagnosis, and medicolegal ramificationsTumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancerMolecular origins of cancer: Molecular basis of colorectal cancerUnbalanced replication as a major source of genetic instability in cancer cellsMicrosatellite instability in colorectal cancerComprehensive molecular characterization of human colon and rectal cancerSelTarbase, a database of human mononucleotide-microsatellite mutations and their potential impact to tumorigenesis and immunologyGenetic reconstruction of individual colorectal tumor historieshMLH1 promoter hypermethylation is an early event in human endometrial tumorigenesisSeven new mutations in hMSH2, an HNPCC gene, identified by denaturing gradient-gel electrophoresisHuman cancers express a mutator phenotypeLoss of CDX2 expression and microsatellite instability are prominent features of large cell minimally differentiated carcinomas of the colonMicrosatellite instability as prognostic marker in bladder tumors: a clinical significanceTumor suppressor gene E-cadherin and its role in normal and malignant cellsHomologous Recombination and Its Role in CarcinogenesisColorectal cancers with microsatellite instability display mRNA expression signatures characteristic of increased immunogenicity.Genome characteristics of primary carcinomas, local recurrences, carcinomatoses, and liver metastases from colorectal cancer patientsTwo modes of microsatellite instability in human cancer: differential connection of defective DNA mismatch repair to dinucleotide repeat instability.Does tumorigenesis select for or against mutations of the DNA repair-associated genes BRCA2 and MRE11?: considerations from somatic mutations in microsatellite unstable (MSI) gastrointestinal cancers.Molecular Genetics of Intracranial Meningiomas with Emphasis on Canonical Wnt SignallingManipulation of DNA Repair Proficiency in Mouse Models of Colorectal CancerCell-based Immunotherapy for Colorectal Cancer with Cytokine-induced Killer CellsPrognostic and predictive markers in stage II colon cancer: is there a role for gene expression profiling?Tumor-specific microsatellite instability: do distinct mechanisms underlie the MSI-L and EMAST phenotypes?DNA polymerase delta in DNA replication and genome maintenanceEMAST is a Form of Microsatellite Instability That is Initiated by Inflammation and Modulates Colorectal Cancer ProgressionCausal link between microsatellite instability and hMRE11 dysfunction in human cancers
P2860
Q21092762-981C7168-225B-4E39-AACE-73EAB402CC9CQ21133026-902A44CD-5BCA-4A5A-9C48-5A8564165BBFQ21145264-E8719EB1-95C1-47A9-BB4B-B4183A34840FQ21328691-D8A06914-5442-4581-963F-3559841E2C40Q24292772-6C1E0C10-AF1E-40F8-A05F-907D4802D424Q24305132-8F95B4E9-C9B6-46A9-A8D7-796BA94B5A8BQ24535557-1F966176-FCF9-4F62-891B-D88C26F7843FQ24548535-6782779B-0AC4-4DBA-A91A-2FD4C000D4B7Q24553992-DEAF77B6-EF1B-4A63-B477-DEA9AE72EFF4Q24555183-CC0D59F5-D468-4D52-A9FC-02D3289B7C4EQ24561717-210388D9-5644-45AD-8A41-0EF1C13E8DAFQ24596823-D32F20BF-75B4-424E-80D2-983000DD72A9Q24603535-492DD331-BD10-42A8-828B-140CD01BFCCFQ24610838-AE3DC9B4-5044-44E1-9BD4-A5F92032F64BQ24614511-1380670A-1568-4661-B759-8D9ABB96CC1EQ24617331-C6932356-E492-4E6A-BD1D-8ADED8C45210Q24621737-9C6BC19C-2286-425A-AA09-D143494F6AE2Q24627393-D9494370-78CA-474C-956C-03D454E4C8CEQ24630415-4FCD1D9C-1832-4646-AAC4-9157FBFEFED4Q24643420-9671E740-E8F2-425C-B35E-9FD5BB6EE0FAQ24670186-1EC603F2-0690-4648-8F4B-F285CD636BEFQ24670424-A6EBF496-CAE2-4740-966B-0F324C07E47FQ24671692-D80D751D-4FB7-42E8-9626-7DC08B575312Q24673022-228445E7-D3EB-4209-BB63-FEC3FC544BC6Q24685680-E12046DF-F4A5-486F-A3E4-1BD117697BEEQ24792206-0A03248E-999E-46DA-84D3-5628FA06C926Q24793413-66AF5A7D-C407-4389-A61D-F35F6BAFEB47Q24793756-33EE1D11-2665-4D41-845A-35887D5E0190Q24800999-E76D2C70-FDF9-4CFE-8E49-2BAD8C22FCFEQ24801499-13ABAE78-95AC-4516-ADA8-47C189DC358CQ24804629-EDF64FEA-92DB-459F-9976-D2CE600B16E8Q25257372-CFACD6F0-39BC-40CA-9F74-C6963154BCD0Q26739662-798B27B7-BB25-40D4-AF0E-17AA71657E87Q26740310-DEDCF350-6464-4859-9D76-4E65B36AD0F2Q26751018-166A197B-42C6-45DB-9047-61060A16CAE6Q26830362-BBA03023-28D9-4E4A-989A-806564A3CF7FQ26864622-B46DB297-A4B1-4712-8897-AD2954A4164FQ26991961-08635B37-5D35-4658-ADF2-FE04FCA6C4F1Q26995653-F3C72472-B411-4546-9486-E62302888FB7Q27026386-9B655B1C-3814-409E-BAB9-61FA465534FD
P2860
Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis
description
1993 nî lūn-bûn
@nan
1993 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Ubiquitous somatic mutations i ...... ism for colonic carcinogenesis
@ast
Ubiquitous somatic mutations i ...... ism for colonic carcinogenesis
@en
Ubiquitous somatic mutations i ...... ism for colonic carcinogenesis
@en-gb
Ubiquitous somatic mutations i ...... ism for colonic carcinogenesis
@nl
type
label
Ubiquitous somatic mutations i ...... ism for colonic carcinogenesis
@ast
Ubiquitous somatic mutations i ...... ism for colonic carcinogenesis
@en
Ubiquitous somatic mutations i ...... ism for colonic carcinogenesis
@en-gb
Ubiquitous somatic mutations i ...... ism for colonic carcinogenesis
@nl
prefLabel
Ubiquitous somatic mutations i ...... ism for colonic carcinogenesis
@ast
Ubiquitous somatic mutations i ...... ism for colonic carcinogenesis
@en
Ubiquitous somatic mutations i ...... ism for colonic carcinogenesis
@en-gb
Ubiquitous somatic mutations i ...... ism for colonic carcinogenesis
@nl
P2093
P3181
P356
P1433
P1476
Ubiquitous somatic mutations i ...... ism for colonic carcinogenesis
@en
P2093
Darryl Shibata
Sergei Malkhosyan
Yurij Ionov
P2888
P304
P3181
P356
10.1038/363558A0
P407
P577
1993-06-10T00:00:00Z
P6179
1043263395