DNA polymerase delta in DNA replication and genome maintenance - Test2 - elhamkhani - TriplyDB

DNA polymerase delta in DNA replication and genome maintenance

DNA polymerase delta in DNA replication and genome maintenance

http://www.wikidata.org/entity/Q26991961

about

An in-frame deletion at the polymerase active site of POLD1 causes a multisystem disorder with lipodystrophy The current state of eukaryotic DNA base damage and repair Sources of DNA double-strand breaks and models of recombinational DNA repair Germline mutation rates and the long-term phenotypic effects of mutation accumulation in wild-type laboratory mice and mutator mice New insights into the mechanism of DNA mismatch repair Replicative DNA polymerase δ but not ε proofreads errors in Cis and in Trans Human POLD1 modulates cell cycle progression and DNA damage repair A synthetic lethal screen identifies ATR-inhibition as a novel therapeutic approach for POLD1-deficient cancers PDIP46 (DNA polymerase δ interacting protein 46) is an activating factor for human DNA polymerase δ A panoply of errors: polymerase proofreading domain mutations in cancer The tail that wags the dog: p12, the smallest subunit of DNA polymerase δ, is degraded by ubiquitin ligases in response to DNA damage and during cell cycle progression An overview of Y-Family DNA polymerases and a case study of human DNA polymerase η The POLD3 subunit of DNA polymerase δ can promote translesion synthesis independently of DNA polymerase ζ.Loss of Pol32 in Drosophila melanogaster causes chromosome instability and suppresses variegation.The arabidopsis DNA polymerase δ has a role in the deposition of transcriptionally active epigenetic marks, development and flowering.A substitution in the fingers domain of DNA polymerase δ reduces fidelity by altering nucleotide discrimination in the catalytic site.Divalent ions attenuate DNA synthesis by human DNA polymerase α by changing the structure of the template/primer or by perturbing the polymerase reaction.Viral and Cellular Components of AAV2 Replication Compartments.Dynamics of enzymatic interactions during short flap human Okazaki fragment processing by two forms of human DNA polymerase δ.POLD1: Central mediator of DNA replication and repair, and implication in cancer and other pathologies Translesion Synthesis: Insights into the Selection and Switching of DNA Polymerases.Close encounters: Moving along bumps, breaks, and bubbles on expanded trinucleotide tracts.The catalytic subunit of DNA polymerase δ inhibits γTuRC activity and regulates Golgi-derived microtubules.Roles of human POLD1 and POLD3 in genome stability.A Redox Role for the [4Fe4S] Cluster of Yeast DNA Polymerase δ.Human DNA polymerase delta double-mutant D316A;E318A interferes with DNA mismatch repair in vitro.The Second Subunit of DNA Polymerase Delta Is Required for Genomic Stability and Epigenetic Regulation.DNA polymerase delta polymerizes DNA across single stranded gap DNA polymerases and their role in genomic stability.

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P2860

DNA polymerase delta in DNA replication and genome maintenance

http://www.wikidata.org/entity/Q26991961

description

2012 nî lūn-bûn

@nan

2012 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2012年の論文

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2012年論文

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2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

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2012年论文

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name

DNA polymerase delta in DNA replication and genome maintenance

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DNA polymerase delta in DNA replication and genome maintenance

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DNA polymerase delta in DNA replication and genome maintenance

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type

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DNA polymerase delta in DNA replication and genome maintenance

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DNA polymerase delta in DNA replication and genome maintenance

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DNA polymerase delta in DNA replication and genome maintenance

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DNA polymerase delta in DNA replication and genome maintenance

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DNA polymerase delta in DNA replication and genome maintenance

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DNA polymerase delta in DNA replication and genome maintenance

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Environmental and Molecular Mutagenesis

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DNA polymerase delta in DNA replication and genome maintenance

@en

P2093

Lawrence A. Loeb

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Marc J. Prindle

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P2860

Isolation and identification of the third subunit of mammalian DNA polymerase delta by PCNA-affinity chromatography of mouse FM3A cell extracts

Eukaryotic DNA Polymerases

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

Identification of a fourth subunit of mammalian DNA polymerase delta

Involvement of DNA polymerase delta in DNA repair synthesis in human fibroblasts at late times after ultraviolet irradiation

Three DNA polymerases, recruited by different mechanisms, carry out NER repair synthesis in human cells

DNA polymerase delta is required for human mismatch repair in vitro

Idling by DNA polymerase delta maintains a ligatable nick during lagging-strand DNA replication

Structural basis of high-fidelity DNA synthesis by yeast DNA polymerase delta

The 3'-->5' exonuclease of DNA polymerase delta can substitute for the 5' flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability

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666-82

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scholarly article

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10.1002/EM.21745

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9

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53

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2012-12-01T00:00:00Z

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23065663

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3694620

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