Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction
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GBF1 bears a novel phosphatidylinositol-phosphate binding module, BP3K, to link PI3Kγ activity with Arf1 activation involved in GPCR-mediated neutrophil chemotaxis and superoxide productionDevelopment, migration, and survival of mast cellsParallel phosphatidylinositol 3-kinase (PI3K)-dependent and Src-dependent pathways lead to CXCL8-mediated Rac2 activation and chemotaxisInternational Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the formyl peptide receptor (FPR) familyThe Novel Functions of the PLC/PKC/PKD Signaling Axis in G Protein-Coupled Receptor-Mediated Chemotaxis of NeutrophilsFocus on PTEN RegulationMoving towards a paradigm: common mechanisms of chemotactic signaling in Dictyostelium and mammalian leukocytesPhosphoinositides: tiny lipids with giant impact on cell regulationp21-Activated kinase (PAK) regulates cytoskeletal reorganization and directional migration in human neutrophilsThe Multifaceted Roles of PI3Kγ in Hypertension, Vascular Biology, and InflammationRap1-mediated lymphocyte function-associated antigen-1 activation by the T cell antigen receptor is dependent on phospholipase C-gamma1The phospholipase C isozymes and their regulationSignaling by the phosphoinositide 3-kinase family in immune cellsAn SH2-domain-containing kinase negatively regulates the phosphatidylinositol-3 kinase pathwayCharacterization of membrane-localized and cytosolic Rac-GTPase-activating proteins in human neutrophil granulocytes: contribution to the regulation of NADPH oxidaseSuppression of PLCbeta2 by endotoxin plays a role in the adenosine A(2A) receptor-mediated switch of macrophages from an inflammatory to an angiogenic phenotypeHaematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migrationExpression of phosphoinositide-specific phospholipase C isoforms in native endothelial cellsThe ichq mutant mouse, a model for the human skin disorder harlequin ichthyosis: mapping, keratinocyte culture, and consideration of candidate genes involved in epidermal growth regulationNeutrophil cell surface receptors and their intracellular signal transduction pathways.Pathophysiological roles of interleukin-8/CXCL8 in pulmonary diseases.The determinants of head and neck cancer: Unmasking the PI3K pathway mutationsRolling on E- or P-selectin induces the extended but not high-affinity conformation of LFA-1 in neutrophilsPhosphoinositide 3-kinase gamma required for lipopolysaccharide-induced transepithelial neutrophil trafficking in the lung.Differential sensitivity of phosphatidylinositol 3-kinase p110gamma to isoforms of G protein betagamma dimers.Mechanisms and consequences of neutrophil interaction with the endothelium.The role of endothelial PI3Kgamma activity in neutrophil trafficking.Neutrophils lacking phosphoinositide 3-kinase gamma show loss of directionality during N-formyl-Met-Leu-Phe-induced chemotaxisPlasma membrane organization is essential for balancing competing pseudopod- and uropod-promoting signals during neutrophil polarization and migration.Phosphoinositide 3-kinase activity controls the chemoattractant-mediated activation and adaptation of adenylyl cyclaseTumor suppressor PTEN is a physiologic suppressor of chemoattractant-mediated neutrophil functionsTo stabilize neutrophil polarity, PIP3 and Cdc42 augment RhoA activity at the back as well as signals at the frontLocally controlled inhibitory mechanisms are involved in eukaryotic GPCR-mediated chemosensing.Spatial sensing in fibroblasts mediated by 3' phosphoinositides.RACK1 regulates directional cell migration by acting on G betagamma at the interface with its effectors PLC beta and PI3K gamma.Immunostaining evidence for PI(4,5)P2 localization at the leading edge of chemoattractant-stimulated HL-60 cells.Choreography of cell motility and interaction dynamics imaged by two-photon microscopy in lymphoid organsPolarization of chemoattractant receptor signaling during neutrophil chemotaxisTyrosine kinase Btk regulates E-selectin-mediated integrin activation and neutrophil recruitment by controlling phospholipase C (PLC) gamma2 and PI3Kgamma pathways.Synaptotagmin-mediated vesicle fusion regulates cell migration.
P2860
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P2860
Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction
description
2000 nî lūn-bûn
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2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի փետրվարին հրատարակված գիտական հոդված
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2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Roles of PLC-beta2 and -beta3 ...... t-mediated signal transduction
@ast
Roles of PLC-beta2 and -beta3 ...... t-mediated signal transduction
@en
Roles of PLC-beta2 and -beta3 ...... t-mediated signal transduction
@en-gb
Roles of PLC-beta2 and -beta3 ...... t-mediated signal transduction
@nl
type
label
Roles of PLC-beta2 and -beta3 ...... t-mediated signal transduction
@ast
Roles of PLC-beta2 and -beta3 ...... t-mediated signal transduction
@en
Roles of PLC-beta2 and -beta3 ...... t-mediated signal transduction
@en-gb
Roles of PLC-beta2 and -beta3 ...... t-mediated signal transduction
@nl
prefLabel
Roles of PLC-beta2 and -beta3 ...... t-mediated signal transduction
@ast
Roles of PLC-beta2 and -beta3 ...... t-mediated signal transduction
@en
Roles of PLC-beta2 and -beta3 ...... t-mediated signal transduction
@en-gb
Roles of PLC-beta2 and -beta3 ...... t-mediated signal transduction
@nl
P2093
P1433
P1476
Roles of PLC-beta2 and -beta3 ...... t-mediated signal transduction
@en
P2093
P304
P356
10.1126/SCIENCE.287.5455.1046
P407
P577
2000-02-11T00:00:00Z