Differential sensitivity of phosphatidylinositol 3-kinase p110gamma to isoforms of G protein betagamma dimers.
about
Phosphorylation of P-Rex1 by the cyclic AMP-dependent protein kinase inhibits the phosphatidylinositiol (3,4,5)-trisphosphate and Gbetagamma-mediated regulation of its activity.Differential sensitivity of P-Rex1 to isoforms of G protein betagamma dimers.Inhibition of a background potassium channel by Gq protein alpha-subunits.RACK1 regulates directional cell migration by acting on G betagamma at the interface with its effectors PLC beta and PI3K gamma.Prenylation-deficient G protein gamma subunits disrupt GPCR signaling in the zebrafishInhibition of Gαi activity by Gβγ is mediated by PI 3-kinase-γ- and cSrc-dependent tyrosine phosphorylation of Gαi and recruitment of RGS12.Pituitary adenylate cyclase-activating polypeptide (PACAP)/PAC1HOP1 receptor activation coordinates multiple neurotrophic signaling pathways: Akt activation through phosphatidylinositol 3-kinase gamma and vesicle endocytosis for neuronal survivalAcetylcholine promotes Ca2+ and NO-oscillations in adipocytes implicating Ca2+→NO→cGMP→cADP-ribose→Ca2+ positive feedback loop--modulatory effects of norepinephrine and atrial natriuretic peptideGnb isoforms control a signaling pathway comprising Rac1, Plcβ2, and Plcβ3 leading to LFA-1 activation and neutrophil arrest in vivo.NO triggers RGS4 degradation to coordinate angiogenesis and cardiomyocyte growthLeukocyte arrest: Biomechanics and molecular mechanisms of β2 integrin activationThe role of Gbetagamma subunits in the organization, assembly, and function of GPCR signaling complexesDifferential inhibitor of Gbetagamma signaling to AKT and ERK derived from phosducin-like protein: effect on sphingosine 1-phosphate-induced endothelial cell migration and in vitro angiogenesisGlucagon-like peptide-1 protects beta-cells against apoptosis by increasing the activity of an IGF-2/IGF-1 receptor autocrine loopThe inhibitory effect of Gβγ and Gβ isoform specificity on ENaC activity.Differential localization of G protein βγ subunits.Insulin contributes to fine-tuning of the pancreatic beta-cell response to glucagon-like peptide-1.Identification of transcriptional targets associated with the expression of p210 Bcr-Abl.Characterization of p87PIKAP, a novel regulatory subunit of phosphoinositide 3-kinase gamma that is highly expressed in heart and interacts with PDE3B.Galphaq binds to p110alpha/p85alpha phosphoinositide 3-kinase and displaces Ras.Addition of N-terminal peptide sequences activates the oncogenic and signaling potentials of the catalytic subunit p110α of phosphoinositide-3-kinaseEvaluating PI3 kinase isoforms using Transcreener ADP assays.Galpha q inhibits cardiac L-type Ca2+ channels through phosphatidylinositol 3-kinase.BCR-ABL regulates phosphatidylinositol 3-kinase-p110gamma transcription and activation and is required for proliferation and drug resistance.
P2860
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P2860
Differential sensitivity of phosphatidylinositol 3-kinase p110gamma to isoforms of G protein betagamma dimers.
description
2004 nî lūn-bûn
@nan
2004 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Differential sensitivity of ph ...... of G protein betagamma dimers.
@ast
Differential sensitivity of ph ...... of G protein betagamma dimers.
@en
type
label
Differential sensitivity of ph ...... of G protein betagamma dimers.
@ast
Differential sensitivity of ph ...... of G protein betagamma dimers.
@en
prefLabel
Differential sensitivity of ph ...... of G protein betagamma dimers.
@ast
Differential sensitivity of ph ...... of G protein betagamma dimers.
@en
P2093
P2860
P356
P1476
Differential sensitivity of ph ...... of G protein betagamma dimers.
@en
P2093
Chang-Seon Myung
Gavin McCleery
James C Garrison
Kristi R Kerchner
Nikki Watson
Robert L Clay
William E McIntire
P2860
P304
44554-44562
P356
10.1074/JBC.M406071200
P407
P577
2004-08-18T00:00:00Z