Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton
about
Loss of SMEK, a novel, conserved protein, suppresses MEK1 null cell polarity, chemotaxis, and gene expression defects.A WASp-VASP complex regulates actin polymerization at the plasma membrane.The ADAP/SKAP55 signaling module regulates T-cell receptor-mediated integrin activation through plasma membrane targeting of Rap1Mutational analysis of human profilin I reveals a second PI(4,5)-P2 binding site neighbouring the poly(L-proline) binding siteEarly Signaling in Primary T Cells Activated by Antigen Presenting Cells Is Associated with a Deep and Transient Lamellal Actin NetworkWASp family verprolin-homologous protein-2 (WAVE2) and Wiskott-Aldrich syndrome protein (WASp) engage in distinct downstream signaling interactions at the T cell antigen receptor siteThe Skap-hom Dimerization and PH Domains Comprise a 3′-Phosphoinositide-Gated Molecular SwitchCharacterization of the interaction between zyxin and members of the Ena/vasodilator-stimulated phosphoprotein family of proteinsRecruitment of the actin-binding protein HIP-55 to the immunological synapse regulates T cell receptor signaling and endocytosisPhysical and functional association of c-Src and adhesion and degranulation promoting adaptor protein (ADAP) in osteoclastogenesis in vitroPREL1 provides a link from Ras signalling to the actin cytoskeleton via Ena/VASP proteinsRIAM links the ADAP/SKAP-55 signaling module to Rap1, facilitating T-cell-receptor-mediated integrin activationHematopoietic adaptors in T-cell signaling: potential applications to transplantationADAP-SLP-76 binding differentially regulates supramolecular activation cluster (SMAC) formation relative to T cell-APC conjugationThe N terminus of SKAP55 enables T cell adhesion to TCR and integrin ligands via distinct mechanisms.Physical mechanisms of signal integration by WASP family proteins.ADAP is required for normal alphaIIbbeta3 activation by VWF/GP Ib-IX-V and other agonists.Adaptor FYB (Fyn-binding protein) regulates integrin-mediated adhesion and mediator release: differential involvement of the FYB SH3 domainCritical roles of phosphorylation and actin binding motifs, but not the central proline-rich region, for Ena/vasodilator-stimulated phosphoprotein (VASP) function during cell migration.Recruitment of dynein to the Jurkat immunological synapseSLP-76-ADAP adaptor module regulates LFA-1 mediated costimulation and T cell motility.Functional cooperation between the proteins Nck and ADAP is fundamental for actin reorganization.Immune adaptor ADAP in T cells regulates HIV-1 transcription and cell-cell viral spread via different co-receptorsZyxin is not colocalized with vasodilator-stimulated phosphoprotein (VASP) at lamellipodial tips and exhibits different dynamics to vinculin, paxillin, and VASP in focal adhesions.Fyn binding protein, Fyb, interacts with mammalian actin binding protein, mAbp1.The molecular adapter SLP-76 relays signals from platelet integrin alphaIIbbeta3 to the actin cytoskeleton.The VASP-Spred-Sprouty domain puzzle.Platelet-associated IgAs and impaired GPVI responses in platelets lacking WIP.Deleterious mutation in the FYB gene is associated with congenital autosomal recessive small-platelet thrombocytopenia.Receptor-stimulated oxidation of SHP-2 promotes T-cell adhesion through SLP-76-ADAPContribution of Ena/VASP proteins to intracellular motility of listeria requires phosphorylation and proline-rich core but not F-actin binding or multimerizationDifferential role of SLP-76 domains in T cell development and functionSynergistic regulation of immunoreceptor signaling by SLP-76-related adaptor Clnk and serine/threonine protein kinase HPK-1.Development of a competitive index assay to evaluate the virulence of Listeria monocytogenes actA mutants during primary and secondary infection of mice.WASp verprolin homology, cofilin homology, and acidic region domain-mediated actin polymerization is required for T cell development.Sin: good or bad? A T lymphocyte perspective.The role of the adapter molecule SLP-76 in platelet function.Targeted disruption of the murine zyxin gene.Membrane domains and the immunological synapse: keeping T cells resting and ready.Signalling scaffolds and adaptors in T-cell immunity.
P2860
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P2860
Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton
description
2000 nî lūn-bûn
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2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2000 թվականի ապրիլին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
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2000年论文
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name
Fyn-binding protein (Fyb)/SLP- ...... ling to the actin cytoskeleton
@ast
Fyn-binding protein (Fyb)/SLP- ...... ling to the actin cytoskeleton
@en
Fyn-binding protein (Fyb)/SLP- ...... ling to the actin cytoskeleton
@en-gb
Fyn-binding protein (Fyb)/SLP- ...... ling to the actin cytoskeleton
@nl
type
label
Fyn-binding protein (Fyb)/SLP- ...... ling to the actin cytoskeleton
@ast
Fyn-binding protein (Fyb)/SLP- ...... ling to the actin cytoskeleton
@en
Fyn-binding protein (Fyb)/SLP- ...... ling to the actin cytoskeleton
@en-gb
Fyn-binding protein (Fyb)/SLP- ...... ling to the actin cytoskeleton
@nl
prefLabel
Fyn-binding protein (Fyb)/SLP- ...... ling to the actin cytoskeleton
@ast
Fyn-binding protein (Fyb)/SLP- ...... ling to the actin cytoskeleton
@en
Fyn-binding protein (Fyb)/SLP- ...... ling to the actin cytoskeleton
@en-gb
Fyn-binding protein (Fyb)/SLP- ...... ling to the actin cytoskeleton
@nl
P2093
P2860
P921
P3181
P356
P1476
Fyn-binding protein (Fyb)/SLP- ...... ling to the actin cytoskeleton
@en
P2093
P2860
P304
P3181
P356
10.1083/JCB.149.1.181
P407
P577
2000-04-01T00:00:00Z