Isolation of a novel gene mutated in Wiskott-Aldrich syndrome
about
The WASP and WAVE family proteinsWAVE, a novel WASP-family protein involved in actin reorganization induced by RacFyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeletonA Dictyostelium homologue of WASP is required for polarized F-actin assembly during chemotaxisRole of RacC for the regulation of WASP and phosphatidylinositol 3-kinase during chemotaxis of DictyosteliumA conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPasesSCAR, a WASP-related protein, isolated as a suppressor of receptor defects in late Dictyostelium developmentWiskott-Aldrich syndrome protein is involved in alphaIIb beta3-mediated cell adhesionThe Cdc42/Rac interactive binding region motif of the Wiskott Aldrich syndrome protein (WASP) is necessary but not sufficient for tight binding to Cdc42 and structure formationWIP, a protein associated with wiskott-aldrich syndrome protein, induces actin polymerization and redistribution in lymphoid cellsInteraction of Nck-associated protein 1 with activated GTP-binding protein RacNeural Wiskott-Aldrich syndrome protein is implicated in the actin-based motility of Shigella flexneriAn autosomal dominant thrombocytopenia gene maps to chromosomal region 10p.X-Linked syndrome of polyendocrinopathy, immune dysfunction, and diarrhea maps to Xp11.23-Xq13.3.Actin-based motility of intracellular microbial pathogensWiskott-Aldrich syndrome protein is associated with the adapter protein Grb2 and the epidermal growth factor receptor in living cellsDirect interaction of the Wiskott-Aldrich syndrome protein with the GTPase Cdc42Syndapin I, a synaptic dynamin-binding protein that associates with the neural Wiskott-Aldrich syndrome proteinCofilin activation in peripheral CD4 T cells of HIV-1 infected patients: a pilot studyWiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domainsWiskott-Aldrich syndrome protein regulates podosomes in primary human macrophagesThe Wiskott-Aldrich syndromeActivation of the CDC42 effector N-WASP by the Shigella flexneri IcsA protein promotes actin nucleation by Arp2/3 complex and bacterial actin-based motilityInherited platelet disorders: toward DNA-based diagnosisActin nucleators in the nucleus: an emerging themeWIP remodeling actin behind the scenes: how WIP reshapes immune and other functionsHematopoietic stem cell gene therapy:assessing the relevance of preclinical modelsUnder lock and key: spatiotemporal regulation of WASP family proteins coordinates separate dynamic cellular processesActin cytoskeletal defects in immunodeficiencyImmunological responses and actin dynamics in macrophages are controlled by N-cofilin but are independent from ADFMultiple WASP-interacting protein recognition motifs are required for a functional interaction with N-WASPBee1, a yeast protein with homology to Wiscott-Aldrich syndrome protein, is critical for the assembly of cortical actin cytoskeletonCdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity.Role of the WASP and WAVE family proteins in breast cancer invasion and metastasisCdc42-interacting protein 4 mediates binding of the Wiskott-Aldrich syndrome protein to microtubulesA mutation in the pleckstrin homology (PH) domain of the FGD1 gene in an Italian family with faciogenital dysplasia (Aarskog-Scott syndrome)GRB2 links signaling to actin assembly by enhancing interaction of neural Wiskott-Aldrich syndrome protein (N-WASp) with actin-related protein (ARP2/3) complexThe human WASP-interacting protein, WIP, activates the cell polarity pathway in yeastThe rat homologue of Wiskott-Aldrich syndrome protein (WASP)-interacting protein (WIP) associates with actin filaments, recruits N-WASP from the nucleus, and mediates mobilization of actin from stress fibers in favor of filopodia formationRich, a rho GTPase-activating protein domain-containing protein involved in signaling by Cdc42 and Rac1
P2860
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P2860
Isolation of a novel gene mutated in Wiskott-Aldrich syndrome
description
1994 nî lūn-bûn
@nan
1994 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Isolation of a novel gene mutated in Wiskott-Aldrich syndrome
@ast
Isolation of a novel gene mutated in Wiskott-Aldrich syndrome
@en
Isolation of a novel gene mutated in Wiskott-Aldrich syndrome
@en-gb
Isolation of a novel gene mutated in Wiskott-Aldrich syndrome
@nl
type
label
Isolation of a novel gene mutated in Wiskott-Aldrich syndrome
@ast
Isolation of a novel gene mutated in Wiskott-Aldrich syndrome
@en
Isolation of a novel gene mutated in Wiskott-Aldrich syndrome
@en-gb
Isolation of a novel gene mutated in Wiskott-Aldrich syndrome
@nl
prefLabel
Isolation of a novel gene mutated in Wiskott-Aldrich syndrome
@ast
Isolation of a novel gene mutated in Wiskott-Aldrich syndrome
@en
Isolation of a novel gene mutated in Wiskott-Aldrich syndrome
@en-gb
Isolation of a novel gene mutated in Wiskott-Aldrich syndrome
@nl
P2093
P921
P3181
P1433
P1476
Isolation of a novel gene mutated in Wiskott-Aldrich syndrome
@en
P2093
P304
P3181
P356
10.1016/0092-8674(94)90528-2
P407
P577
1994-08-26T00:00:00Z