Identification and characterization of a novel inositol polyphosphate 5-phosphatase
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Identification of a novel domain in two mammalian inositol-polyphosphate 5-phosphatases that mediates membrane ruffle localization. The inositol 5-phosphatase skip localizes to the endoplasmic reticulum and translocates to membrane ruffles ...SKIP negatively regulates insulin-induced GLUT4 translocation and membrane ruffle formation.Silencer of death domains (SODD) inhibits skeletal muscle and kidney enriched inositol 5-phosphatase (SKIP) and regulates phosphoinositide 3-kinase (PI3K)/Akt signaling to the actin cytoskeletonIncreased insulin action in SKIP heterozygous knockout miceThe SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actinIdentification and characterization of a sac domain-containing phosphoinositide 5-phosphataseThe inositol Inpp5k 5-phosphatase affects osmoregulation through the vasopressin-aquaporin 2 pathway in the collecting systemMutations in INPP5K, Encoding a Phosphoinositide 5-Phosphatase, Cause Congenital Muscular Dystrophy with Cataracts and Mild Cognitive ImpairmentA novel receptor-mediated regulation mechanism of type I inositol polyphosphate 5-phosphatase by calcium/calmodulin-dependent protein kinase II phosphorylation.Regulation of insulin signaling by the phosphatidylinositol 3,4,5-triphosphate phosphatase SKIP through the scaffolding function of Pak1Regulation of insulin signaling and glucose transporter 4 (GLUT4) exocytosis by phosphatidylinositol 3,4,5-trisphosphate (PIP3) phosphatase, skeletal muscle, and kidney enriched inositol polyphosphate phosphatase (SKIP).Identification of Mycobacterium avium pathogenicity island important for macrophage and amoeba infectionIntracellular signalling mechanisms regulating glucose transport in insulin-sensitive tissues (review).Miller-Dieker syndrome: analysis of a human contiguous gene syndrome in the mouse.The structure of phosphoinositide phosphatases: Insights into substrate specificity and catalysis.p21-Activated protein kinases and their emerging roles in glucose homeostasis.Inositol lipid phosphatases in membrane trafficking and human disease.Differential SKIP expression in PTEN-deficient glioblastoma regulates cellular proliferation and migration.Phosphatidylinositol 3-phosphate [PtdIns3P] is generated at the plasma membrane by an inositol polyphosphate 5-phosphatase: endogenous PtdIns3P can promote GLUT4 translocation to the plasma membrane.Phosphatidylinositolphosphate phosphatase activities and cancer.Mutations in INPP5K Cause a Form of Congenital Muscular Dystrophy Overlapping Marinesco-Sjögren Syndrome and Dystroglycanopathy.The control of phosphatidylinositol 3,4-bisphosphate concentrations by activation of the Src homology 2 domain containing inositol polyphosphate 5-phosphatase 2, SHIP2.Role of phosphatidylinositol 3,4,5-trisphosphate (PIP3) 5-phosphatase skeletal muscle- and kidney-enriched inositol polyphosphate phosphatase (SKIP) in myoblast differentiation.Phosphatidylinositol 3,4,5-Trisphosphate Phosphatase SKIP Links Endoplasmic Reticulum Stress in Skeletal Muscle to Insulin Resistance.PTEN, but not SHIP2, suppresses insulin signaling through the phosphatidylinositol 3-kinase/Akt pathway in 3T3-L1 adipocytes.Identification of cyclin A2 as the downstream effector of the nuclear phosphatidylinositol 4,5-bisphosphate signaling network.FRAGILE FIBER3, an Arabidopsis gene encoding a type II inositol polyphosphate 5-phosphatase, is required for secondary wall synthesis and actin organization in fiber cells.Dual 4- and 5-phosphatase activities regulate SopB-dependent phosphoinositide dynamics to promote bacterial entry.PI(4;5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membranePI(3;4;5)P3 is dephosphorylated to PI(3;4)P2 by INPP5[2] at the plasma membraneInpp5e suppresses polycystic kidney disease via inhibition of PI3K/Akt-dependent mTORC1 signaling.The inositol 5-phosphatase INPP5K participates in the fine control of ER organizationLipid membrane curvature induced by distearoyl phosphatidylinositol 4-phosphate
P2860
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P2860
Identification and characterization of a novel inositol polyphosphate 5-phosphatase
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2000 nî lūn-bûn
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2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2000 թվականի ապրիլին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
Identification and characterization of a novel inositol polyphosphate 5-phosphatase
@ast
Identification and characterization of a novel inositol polyphosphate 5-phosphatase
@en
Identification and characterization of a novel inositol polyphosphate 5-phosphatase
@nl
type
label
Identification and characterization of a novel inositol polyphosphate 5-phosphatase
@ast
Identification and characterization of a novel inositol polyphosphate 5-phosphatase
@en
Identification and characterization of a novel inositol polyphosphate 5-phosphatase
@nl
prefLabel
Identification and characterization of a novel inositol polyphosphate 5-phosphatase
@ast
Identification and characterization of a novel inositol polyphosphate 5-phosphatase
@en
Identification and characterization of a novel inositol polyphosphate 5-phosphatase
@nl
P2093
P2860
P356
P1476
Identification and characterization of a novel inositol polyphosphate 5-phosphatase
@en
P2093
P2860
P304
P356
10.1074/JBC.275.15.10870
P407
P577
2000-04-14T00:00:00Z