Identification of a novel domain in two mammalian inositol-polyphosphate 5-phosphatases that mediates membrane ruffle localization. The inositol 5-phosphatase skip localizes to the endoplasmic reticulum and translocates to membrane ruffles ...
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Silencer of death domains (SODD) inhibits skeletal muscle and kidney enriched inositol 5-phosphatase (SKIP) and regulates phosphoinositide 3-kinase (PI3K)/Akt signaling to the actin cytoskeletonIncreased insulin action in SKIP heterozygous knockout miceEssential role for TAX1BP1 in the termination of TNF-alpha-, IL-1- and LPS-mediated NF-kappaB and JNK signalingThe type Ialpha inositol polyphosphate 4-phosphatase generates and terminates phosphoinositide 3-kinase signals on endosomes and the plasma membraneT6BP and NDP52 are myosin VI binding partners with potential roles in cytokine signalling and cell adhesion.Role of the N-terminal activation domain of the coiled-coil coactivator in mediating transcriptional activation by beta-cateninPhosphoinositides: tiny lipids with giant impact on cell regulationThe inositol Inpp5k 5-phosphatase affects osmoregulation through the vasopressin-aquaporin 2 pathway in the collecting systemThe inositol polyphosphate 5-phosphatase, PIPP, Is a novel regulator of phosphoinositide 3-kinase-dependent neurite elongation.Regulation of PI3K effector signalling in cancer by the phosphoinositide phosphatasesMutations in INPP5K, Encoding a Phosphoinositide 5-Phosphatase, Cause Congenital Muscular Dystrophy with Cataracts and Mild Cognitive ImpairmentGlucose-regulated protein 78 (GRP78) binds directly to PIP3 phosphatase SKIP and determines its localization.Crystallographic and modelling studies suggest that the SKICH domains from different protein families share a common Ig-like fold but harbour substantial structural variations.Regulation of insulin signaling by the phosphatidylinositol 3,4,5-triphosphate phosphatase SKIP through the scaffolding function of Pak1Expression, purification and crystallization of the SKICH domain of human TAX1BP1Influence of proline-rich inositol polyphosphate 5-phosphatase, on early development of fertilized mouse eggs, via inhibition of phosphorylation of Akt.Alteration of epithelial structure and function associated with PtdIns(4,5)P2 degradation by a bacterial phosphatase.Identification of a proline-rich inositol polyphosphate 5-phosphatase (PIPP)•collapsin response mediator protein 2 (CRMP2) complex that regulates neurite elongation.The structure of phosphoinositide phosphatases: Insights into substrate specificity and catalysis.The CIL-1 PI 5-phosphatase localizes TRP Polycystins to cilia and activates sperm in C. elegans.Deubiquitinases in the regulation of NF-κB signaling.Inositol lipid phosphatases in membrane trafficking and human disease.Differential SKIP expression in PTEN-deficient glioblastoma regulates cellular proliferation and migration.Phosphatidylinositolphosphate phosphatase activities and cancer.Following the trail of lipids: Signals initiated by PI3K function at multiple cellular membranes.Mutations in INPP5K Cause a Form of Congenital Muscular Dystrophy Overlapping Marinesco-Sjögren Syndrome and Dystroglycanopathy.Detection of novel intracellular agonist responsive pools of phosphatidylinositol 3,4-bisphosphate using the TAPP1 pleckstrin homology domain in immunoelectron microscopy.Recruitment of TBK1 to cytosol-invading Salmonella induces WIPI2-dependent antibacterial autophagy.Phosphatidylinositol 3,4,5-Trisphosphate Phosphatase SKIP Links Endoplasmic Reticulum Stress in Skeletal Muscle to Insulin Resistance.Identification of cyclin A2 as the downstream effector of the nuclear phosphatidylinositol 4,5-bisphosphate signaling network.Identification of a novel domain of Ras and Rap1 that directs their differential subcellular localizations.Synthesis of PIPs at the plasma membraneDual 4- and 5-phosphatase activities regulate SopB-dependent phosphoinositide dynamics to promote bacterial entry.PI(4;5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membranePI(3;4;5)P3 is dephosphorylated to PI(3;4)P2 by INPP5[2] at the plasma membraneThe inositol 5-phosphatase INPP5K participates in the fine control of ER organization
P2860
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P248
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P2860
Identification of a novel domain in two mammalian inositol-polyphosphate 5-phosphatases that mediates membrane ruffle localization. The inositol 5-phosphatase skip localizes to the endoplasmic reticulum and translocates to membrane ruffles ...
description
2003 nî lūn-bûn
@nan
2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Identification of a novel doma ...... ocates to membrane ruffles ...
@ast
Identification of a novel doma ...... ocates to membrane ruffles ...
@en
Identification of a novel doma ...... ocates to membrane ruffles ...
@en-gb
Identification of a novel doma ...... ocates to membrane ruffles ...
@nl
type
label
Identification of a novel doma ...... ocates to membrane ruffles ...
@ast
Identification of a novel doma ...... ocates to membrane ruffles ...
@en
Identification of a novel doma ...... ocates to membrane ruffles ...
@en-gb
Identification of a novel doma ...... ocates to membrane ruffles ...
@nl
prefLabel
Identification of a novel doma ...... ocates to membrane ruffles ...
@ast
Identification of a novel doma ...... ocates to membrane ruffles ...
@en
Identification of a novel doma ...... ocates to membrane ruffles ...
@en-gb
Identification of a novel doma ...... ocates to membrane ruffles ...
@nl
P2093
P2860
P50
P921
P3181
P356
P1476
Identification of a novel doma ...... rmal growth factor stimulation
@en
P2093
Adam D Munday
Mark Prescott
Rajendra Gurung
Richard D Huysmans
P2860
P304
11376-11385
P3181
P356
10.1074/JBC.M209991200
P407
P577
2003-01-20T00:00:00Z