about
BRCA1 affects global DNA methylation through regulation of DNMT1DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domainsConstitutive association of BRCA1 and c-Abl and its ATM-dependent disruption after irradiation.Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chainsAlternative splicing in concert with protein intrinsic disorder enables increased functional diversity in multicellular organismsRegulation of RelA (p65) function by the large subunit of replication factor CA requirement for breast-cancer-associated gene 1 (BRCA1) in the spindle checkpointSTRUCTURE-FUNCTION OF THE TUMOR SUPPRESSOR BRCA1Binding and recognition in the assembly of an active BRCA1/BARD1 ubiquitin-ligase complexAssociation of BRCA1 with the inactive X chromosome and XIST RNABRCA1 Zinc RING Finger Domain Disruption Alters Caspase Response in Ovarian Surface Epithelial Cells.Distinct functions of BRCA1 and BRCA2 in double-strand break repairAre Trp53 rescue of Brca1 embryonic lethality and Trp53/Brca1 breast cancer association related?Vestige: maximum likelihood phylogenetic footprintingBRCA1: cell cycle checkpoint, genetic instability, DNA damage response and cancer evolutionFine tuning chemotherapy to match BRCA1 statusPhosphorylated BRCA1 is predominantly located in the nucleus and mitochondriaHigh occurrence of BRCA1 intragenic rearrangements in hereditary breast and ovarian cancer syndrome in the Czech Republic.Function of oval cells in hepatocellular carcinoma in ratsProspective screening study of 0.5 Tesla dedicated magnetic resonance imaging for the detection of breast cancer in young, high-risk women.Yeast screens identify the RNA polymerase II CTD and SPT5 as relevant targets of BRCA1 interaction.Protein disorder in the human diseasome: unfoldomics of human genetic diseases.Distinct implications of different BRCA mutations: efficacy of cytotoxic chemotherapy, PARP inhibition and clinical outcome in ovarian cancerDNA damage response mediated through BRCA1Turnover of BRCA1 involves in radiation-induced apoptosis.The PARP inhibitors, veliparib and olaparib, are effective chemopreventive agents for delaying mammary tumor development in BRCA1-deficient miceDepletion of BRCA1 impairs differentiation but enhances proliferation of mammary epithelial cells.BRCA1 transcriptionally regulates genes involved in breast tumorigenesis.The Met oncogene and basal-like breast cancer: another culprit to watch out for?Conditional knockout of brca1/2 and p53 in mouse ovarian surface epithelium: do they play a role in ovarian carcinogenesis?Drug repurposing screen identifies lestaurtinib amplifies the ability of the poly (ADP-ribose) polymerase 1 inhibitor AG14361 to kill breast cancer associated gene-1 mutant and wild type breast cancer cells.Characterization of Arabidopsis thaliana ortholog of the human breast cancer susceptibility gene 1: AtBRCA1, strongly induced by gamma raysBRCA1 and γH2AX as independent prognostic markers in oral squamous cell carcinoma.Selective removal of the selenocysteine tRNA [Ser]Sec gene (Trsp) in mouse mammary epithelium.PARP-1 inhibitors: are they the long-sought genetically specific drugs for BRCA1/2-associated breast cancers?The breast cancer susceptibility genes (BRCA) in breast and ovarian cancers.Gerosuppressant metformin: less is moreTransgenic and knockout mice models to reveal the functions of tumor suppressor genes.Assessing estrogen signaling aberrations in breast cancer risk using genetically engineered mouse models.The Novel Ribonucleotide Reductase Inhibitor COH29 Inhibits DNA Repair In Vitro
P2860
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P2860
description
2000 nî lūn-bûn
@nan
2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Roles of BRCA1 and its interacting proteins
@ast
Roles of BRCA1 and its interacting proteins
@en
Roles of BRCA1 and its interacting proteins
@en-gb
Roles of BRCA1 and its interacting proteins
@nl
type
label
Roles of BRCA1 and its interacting proteins
@ast
Roles of BRCA1 and its interacting proteins
@en
Roles of BRCA1 and its interacting proteins
@en-gb
Roles of BRCA1 and its interacting proteins
@nl
prefLabel
Roles of BRCA1 and its interacting proteins
@ast
Roles of BRCA1 and its interacting proteins
@en
Roles of BRCA1 and its interacting proteins
@en-gb
Roles of BRCA1 and its interacting proteins
@nl
P3181
P1433
P1476
Roles of BRCA1 and its interacting proteins
@en
P2093
P304
P3181
P356
10.1002/1521-1878(200008)22:8<728::AID-BIES6>3.3.CO;2-2
P407
P577
2000-08-01T00:00:00Z