Lipidomics identifies cardiolipin oxidation as a mitochondrial target for redox therapy of brain injury - Test2 - elhamkhani - TriplyDB

Lipidomics identifies cardiolipin oxidation as a mitochondrial target for redox therapy of brain injury

Lipidomics identifies cardiolipin oxidation as a mitochondrial target for redox therapy of brain injury

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Imaging mass spectrometry of diversified cardiolipin molecular species in the brain Oxidized phospholipids as biomarkers of tissue and cell damage with a focus on cardiolipin Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells Designing inhibitors of cytochrome c/cardiolipin peroxidase complexes: mitochondria-targeted imidazole-substituted fatty acids Deciphering of mitochondrial cardiolipin oxidative signaling in cerebral ischemia-reperfusion Structural re-arrangement and peroxidase activation of cytochrome c by anionic analogues of vitamin E, tocopherol succinate and tocopherol phosphate Cardiolipin asymmetry, oxidation and signaling Cardiolipin signaling mechanisms: collapse of asymmetry and oxidation LC/MS analysis of cardiolipins in substantia nigra and plasma of rotenone-treated rats: implication for mitochondrial dysfunction in Parkinson's disease LC/MS characterization of rotenone induced cardiolipin oxidation in human lymphocytes: implications for mitochondrial dysfunction associated with Parkinson's disease Characterization of cardiolipins and their oxidation products by LC-MS analysis A mitochondrial pathway for biosynthesis of lipid mediators Traumatic Axonal Injury: Mechanisms and Translational Opportunities Barth Syndrome: From Mitochondrial Dysfunctions Associated with Aberrant Production of Reactive Oxygen Species to Pluripotent Stem Cell Studies Evolution of cytochrome bc complexes: from membrane-anchored dehydrogenases of ancient bacteria to triggers of apoptosis in vertebrates Emerging therapies in traumatic brain injury Cerebrospinal Fluid Markers of Macrophage and Lymphocyte Activation After Traumatic Brain Injury in Children First-in-class cardiolipin-protective compound as a therapeutic agent to restore mitochondrial bioenergetics New insights on effects of a dietary supplement on oxidative and nitrosative stress in humans Mitochondrial-derived reactive oxygen species (ROS) play a causal role in aging-related intervertebral disc degeneration Serendipity and the discovery of novel compounds that restore mitochondrial plasticity Metabolic Alterations in Developing Brain After Injury: Knowns and Unknowns Mitochondria-targeted antioxidant preserves contractile properties and mitochondrial function of skeletal muscle in aged rats The membrane-active tri-block copolymer pluronic F-68 profoundly rescues rat hippocampal neurons from oxygen-glucose deprivation-induced death through early inhibition of apoptosis Synthesis of analogs of the radiation mitigator JP4-039 and visualization of BODIPY derivatives in mitochondria Mitochondrial targeting of XJB-5-131 attenuates or improves pathophysiology in HdhQ150 animals with well-developed disease phenotypes.The mitochondrial-targeted compound SS-31 re-energizes ischemic mitochondria by interacting with cardiolipin Mitochondria-targeted ROS scavenger improves post-ischemic recovery of cardiac function and attenuates mitochondrial abnormalities in aged rats Dietary macronutrients modulate the fatty acyl composition of rat liver mitochondrial cardiolipins Contributions of academic laboratories to the discovery and development of chemical biology tools Pharmacological mitigation of tissue damage during brain microdialysis Nutritional lipidomics: molecular metabolism, analytics, and diagnostics Formation of electrophilic oxidation products from mitochondrial cardiolipin in vitro and in vivo in the context of apoptosis and atherosclerosis Inhibition of Eukaryotic Initiation Factor 2 Alpha Phosphatase Reduces Tissue Damage and Improves Learning and Memory after Experimental Traumatic Brain Injury A Mitochondrial-Targeted Nitroxide Is a Potent Inhibitor of Ferroptosis Evaluation of potential ionizing irradiation protectors and mitigators using clonogenic survival of human umbilical cord blood hematopoietic progenitor cells Mitochondrial targeted β-lapachone induces mitochondrial dysfunction and catastrophic vacuolization in cancer cells Sex-specific cardiac cardiolipin remodelling after doxorubicin treatment Repetitive Mild Traumatic Brain Injury in the Developing Brain: Effects on Long-Term Functional Outcome and Neuropathology.Probenecid and N-Acetylcysteine Prevent Loss of Intracellular Glutathione and Inhibit Neuronal Death after Mechanical Stretch Injury In Vitro

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Lipidomics identifies cardiolipin oxidation as a mitochondrial target for redox therapy of brain injury

http://www.wikidata.org/entity/Q23914951

description

2012 nî lūn-bûn

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2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2012 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2012年の論文

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Lipidomics identifies cardioli ...... redox therapy of brain injury

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Lipidomics identifies cardioli ...... redox therapy of brain injury

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Lipidomics identifies cardioli ...... redox therapy of brain injury

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Lipidomics identifies cardioli ...... redox therapy of brain injury

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Lipidomics identifies cardioli ...... redox therapy of brain injury

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Lipidomics identifies cardioli ...... redox therapy of brain injury

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Lipidomics identifies cardioli ...... redox therapy of brain injury

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Lipidomics identifies cardioli ...... redox therapy of brain injury

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Lipidomics identifies cardioli ...... redox therapy of brain injury

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Lipidomics identifies cardioli ...... redox therapy of brain injury

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Lipidomics identifies cardioli ...... redox therapy of brain injury

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Lipidomics identifies cardioli ...... redox therapy of brain injury

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Lipidomics identifies cardioli ...... redox therapy of brain injury

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P2860

Selective early cardiolipin peroxidation after traumatic brain injury: an oxidative lipidomics analysis

Cytochrome c acts as a cardiolipin oxygenase required for release of proapoptotic factors

Chemistry and antihypertensive effects of tempol and other nitroxides

Traumatic brain injury--football, warfare, and long-term effects

Cardiolipin: characterization of distinct oxidized molecular species

Permeabilization of the mitochondrial outer membrane by Bax/truncated Bid (tBid) proteins as sensitized by cardiolipin hydroperoxide translocation: mechanistic implications for the intrinsic pathway of oxidative apoptosis

Mitochondrial injury after mechanical stretch of cortical neurons in vitro: biomarkers of apoptosis and selective peroxidation of anionic phospholipids

Cytochrome c release from mitochondria proceeds by a two-step process.

Transgenic mice overexpressing glutathione peroxidase 4 are protected against oxidative stress-induced apoptosis.

Imaging mass spectrometry revealed the production of lyso-phosphatidylcholine in the injured ischemic rat brain.

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human behaviour

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3697869

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