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Deciphering of mitochondrial cardiolipin oxidative signaling in cerebral ischemia-reperfusionLipidomics identifies cardiolipin oxidation as a mitochondrial target for redox therapy of brain injuryMitochondria-targeted disruptors and inhibitors of cytochrome c/cardiolipin peroxidase complexes: a new strategy in anti-apoptotic drug discoveryMitochondrial targeting of electron scavenging antioxidants: regulation of selective oxidation vs random chain reactionsCytochrome c/cardiolipin relations in mitochondria: a kiss of deathEvaluating beta-turn mimics as beta-sheet folding nucleatorsIterative Structure-Based Peptide-Like Inhibitor Design against the Botulinum Neurotoxin Serotype ATerminal Alkene Formation by the Thioesterase of Curacin A Biosynthesis: STRUCTURE OF A DECARBOXYLATING THIOESTERASEStructural Basis of Functional Group Activation by Sulfotransferases in Complex Metabolic PathwaysTotal Synthesis of (-)-Muscoride AMitochondria as a target in treatmentPeptide-Like Molecules (PLMs): A Journey from Peptide Bond Isosteres to Gramicidin S Mimetics and Mitochondrial Targeting Agents.Strategies for discovery of small molecule radiation protectors and radiation mitigatorsMitochondria-targeted antioxidant preserves contractile properties and mitochondrial function of skeletal muscle in aged ratsSynthesis of analogs of the radiation mitigator JP4-039 and visualization of BODIPY derivatives in mitochondriaMitochondrial targeting of XJB-5-131 attenuates or improves pathophysiology in HdhQ150 animals with well-developed disease phenotypes.Large-scale asymmetric synthesis of the bioprotective agent JP4-039 and analogsTwo strategies for the development of mitochondrion-targeted small molecule radiation damage mitigatorsContributions of academic laboratories to the discovery and development of chemical biology toolsPharmacological mitigation of tissue damage during brain microdialysisA Mitochondrial-Targeted Nitroxide Is a Potent Inhibitor of FerroptosisEvaluation of potential ionizing irradiation protectors and mitigators using clonogenic survival of human umbilical cord blood hematopoietic progenitor cellsMitochondrial targeted β-lapachone induces mitochondrial dysfunction and catastrophic vacuolization in cancer cellsGenetically encoded redox sensor identifies the role of ROS in degenerative and mitochondrial disease pathogenesisBridged tetrahydroisoquinolines as selective NADPH oxidase 2 (Nox2) inhibitorsAntioxidant Approaches to Management of Ionizing Irradiation InjuryCan Radiosensitivity Associated with Defects in DNA Repair be Overcome by Mitochondrial-Targeted Antioxidant RadioprotectorsAllylic Amines as Key Building Blocks in the Synthesis of (E)-Alkene Peptide IsosteresOxidative lipidomics of hyperoxic acute lung injury: mass spectrometric characterization of cardiolipin and phosphatidylserine peroxidationIdentification of potent chemotypes targeting Leishmania major using a high-throughput, low-stringency, computationally enhanced, small molecule screenDiscovery of diverse small molecule chemotypes with cell-based PKD1 inhibitory activity.A targeted library screen reveals a new inhibitor scaffold for protein kinase DDiscovery and validation of a new class of small molecule Toll-like receptor 4 (TLR4) inhibitorsSD-208, a novel protein kinase D inhibitor, blocks prostate cancer cell proliferation and tumor growth in vivo by inducing G2/M cell cycle arrestMolecular pharmacology and antitumor activity of PX-866, a novel inhibitor of phosphoinositide-3-kinase signalingEffectiveness of Analogs of the GS-Nitroxide, JP4-039, as Total Body Irradiation MitigatorsCombined chemical-genetic approach identifies cytosolic HSP70 dependence in rhabdomyosarcomaPlasmodium falciparum encodes a single cytosolic type I Hsp40 that functionally interacts with Hsp70 and is upregulated by heat shockOptimization of pyrazole-containing 1,2,4-triazolo-[3,4-b]thiadiazines, a new class of STAT3 pathway inhibitorsPhotooxygenation of an amino-thienopyridone yields a more potent PTP4A3 inhibitor.
P50
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P50
description
scheikundige
@nl
name
Peter Wipf
@ast
Peter Wipf
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Peter Wipf
@es
Peter Wipf
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Peter Wipf
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type
label
Peter Wipf
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Peter Wipf
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Peter Wipf
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Peter Wipf
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Peter Wipf
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prefLabel
Peter Wipf
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Peter Wipf
@en
Peter Wipf
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Peter Wipf
@nl
Peter Wipf
@sl