Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling
about
The CK1 Family: Contribution to Cellular Stress Response and Its Role in CarcinogenesisWnt signaling pathways in urological cancers: past decades and still growingEpigenetic silencing of AXIN2 in colorectal carcinoma with microsatellite instabilityActivation of AXIN2 expression by beta-catenin-T cell factor. A feedback repressor pathway regulating Wnt signalingA coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)Subcellular distribution of Wnt pathway proteins in normal and neoplastic colonDACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modificationsMutations in AXIN2 cause familial tooth agenesis and predispose to colorectal cancerThe kinase TNIK is an essential activator of Wnt target genesWnt11 signaling promotes proliferation, transformation, and migration of IEC6 intestinal epithelial cells.Wnt/beta-catenin signaling and small molecule inhibitorsWnt/beta-catenin signaling: components, mechanisms, and diseasesA genome-wide RNAi screen for Wnt/beta-catenin pathway components identifies unexpected roles for TCF transcription factors in cancerAssociation of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcomeWnt signaling: the good and the badPCAF acetylates {beta}-catenin and improves its stabilityThe links between axin and carcinogenesisNr-CAM is a target gene of the beta-catenin/LEF-1 pathway in melanoma and colon cancer and its expression enhances motility and confers tumorigenesisGli1, downregulated in colorectal cancers, inhibits proliferation of colon cancer cells involving Wnt signalling activationLoss of CDX2 expression and microsatellite instability are prominent features of large cell minimally differentiated carcinomas of the colonRegulation of CTNNB1 signaling in gastric cancer and stem cellsS100A4 in Cancer Metastasis: Wnt Signaling-Driven Interventions for Metastasis RestrictionDevelopment of anticancer agents targeting the Wnt/β-catenin signalingAdult mammalian stem cells: the role of Wnt, Lgr5 and R-spondinsImmunotherapy in human colorectal cancer: Challenges and prospectiveThe crosstalk between microRNAs and the Wnt/β-catenin signaling pathway in cancerBeta-catenin--a linchpin in colorectal carcinogenesis?Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomasColorectal cancer and genetic alterations in the Wnt pathwayThe β-catenin destruction complexExpression of axin2 is regulated by the alternative 5'-untranslated regions of its mRNAHEF1, a novel target of Wnt signaling, promotes colonic cell migration and cancer progressionGenetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivoThe leukemia-associated Mllt10/Af10-Dot1l are Tcf4/β-catenin coactivators essential for intestinal homeostasisActivation of the transcription factor GLI1 by WNT signaling underlies the role of SULFATASE 2 as a regulator of tissue regenerationLong-term feeding of various fat diets modulates azoxymethane-induced colon carcinogenesis through Wnt/beta-catenin signaling in ratsWnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway.Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumorsWnt signalling in stem cells and cancerMutations in the human naked cuticle homolog NKD1 found in colorectal cancer alter Wnt/Dvl/beta-catenin signaling
P2860
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P2860
Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling
description
2000 nî lūn-bûn
@nan
2000 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Mutations in AXIN2 cause color ...... ng beta-catenin/TCF signalling
@ast
Mutations in AXIN2 cause color ...... ng beta-catenin/TCF signalling
@en
Mutations in AXIN2 cause color ...... ng beta-catenin/TCF signalling
@en-gb
Mutations in AXIN2 cause color ...... ng beta-catenin/TCF signalling
@nl
type
label
Mutations in AXIN2 cause color ...... ng beta-catenin/TCF signalling
@ast
Mutations in AXIN2 cause color ...... ng beta-catenin/TCF signalling
@en
Mutations in AXIN2 cause color ...... ng beta-catenin/TCF signalling
@en-gb
Mutations in AXIN2 cause color ...... ng beta-catenin/TCF signalling
@nl
prefLabel
Mutations in AXIN2 cause color ...... ng beta-catenin/TCF signalling
@ast
Mutations in AXIN2 cause color ...... ng beta-catenin/TCF signalling
@en
Mutations in AXIN2 cause color ...... ng beta-catenin/TCF signalling
@en-gb
Mutations in AXIN2 cause color ...... ng beta-catenin/TCF signalling
@nl
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Mutations in AXIN2 cause color ...... ng beta-catenin/TCF signalling
@en
P2093
E Christensen
K C Halling
K K Krishnadath
K Taniguchi
L A Boardman
R S Seelan
P2860
P2888
P3181
P356
10.1038/79859
P407
P577
2000-10-01T00:00:00Z
P6179
1027563146