Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting
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The kinase DYRK1A phosphorylates the transcription factor FKHR at Ser329 in vitro, a novel in vivo phosphorylation siteAkt- and Foxo1-interacting WD-repeat-FYVE protein promotes adipogenesisDifferential 14-3-3 affinity capture reveals new downstream targets of phosphatidylinositol 3-kinase signalingAntagonistic effects of phorbol esters on insulin regulation of insulin-like growth factor-binding protein-1 (IGFBP-1) but not glucose-6-phosphatase gene expressionAcetylation of Foxo1 alters its DNA-binding ability and sensitivity to phosphorylationTwo novel phosphorylation sites on FKHR that are critical for its nuclear exclusionInsulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation14-3-3s regulate fructose-2,6-bisphosphate levels by binding to PKB-phosphorylated cardiac fructose-2,6-bisphosphate kinase/phosphataseGlycogen synthase kinase-3 regulates IGFBP-1 gene transcription through the thymine-rich insulin response elementExpression of Drosophila FOXO regulates growth and can phenocopy starvationRNA-processing protein TDP-43 regulates FOXO-dependent protein quality control in stress responseLigand-dependent interaction of estrogen receptor-alpha with members of the forkhead transcription factor familyRegulation and physiological roles of serum- and glucocorticoid-induced protein kinase isoformsNeutrophil activation by fMLP regulates FOXO (forkhead) transcription factors by multiple pathways, one of which includes the binding of FOXO to the survival factor Mcl-1Phenobarbital confers its diverse effects by activating the orphan nuclear receptor carNuclear-cytoplasmic shuttling of a RING-IBR protein RBCK1 and its functional interaction with nuclear body proteinsFoxO6 transcriptional activity is regulated by Thr26 and Ser184, independent of nucleo-cytoplasmic shuttlingFoxO6, a novel member of the FoxO class of transcription factors with distinct shuttling dynamicsThe B55α-containing PP2A holoenzyme dephosphorylates FOXO1 in islet β-cells under oxidative stressInsulin regulation of insulin-like growth factor-binding protein-1 gene expression is dependent on the mammalian target of rapamycin, but independent of ribosomal S6 kinase activityInvestigation of salicylate hepatic responses in comparison with chemical analogues of the drugPP2A regulates the pro-apoptotic activity of FOXO1.Insulin-response element-binding protein 1: a novel Akt substrate involved in transcriptional action of insulin.Bimodal regulation of FoxO3 by AKT and 14-3-314-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transportOver-expression of 14-3-3zeta is an early event in oral cancer.Identification and analysis of evolutionary selection pressures acting at the molecular level in five forkhead subfamilies.14-3-3 protein masks the DNA binding interface of forkhead transcription factor FOXO4.Oxidative stress activates the transcription factors FoxO 1a and FoxO 3a in the hippocampus of rats exposed to low doses of ozoneInsulin signaling, resistance, and the metabolic syndrome: insights from mouse models into disease mechanisms.Uncoupling of acetylation from phosphorylation regulates FoxO1 function independent of its subcellular localization.FoxO1 links hepatic insulin action to endoplasmic reticulum stress.The double-stranded RNA-dependent protein kinase differentially regulates insulin receptor substrates 1 and 2 in HepG2 cellsFoxO, autophagy, and cardiac remodeling.14-3-3sigma regulates B-cell homeostasis through stabilization of FOXO1.FoxO1 is required for the regulation of preproglucagon gene expression by insulin in pancreatic alphaTC1-9 cells.Induction of cyclin D2 in rat granulosa cells requires FSH-dependent relief from FOXO1 repression coupled with positive signals from SmadProtein tyrosine phosphatase-1B modulates pancreatic β-cell massFOXO1 is regulated by insulin and IGF1 in pituitary gonadotropes.Role of transcription factor modifications in the pathogenesis of insulin resistance.
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P2860
Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting
description
2001 nî lūn-bûn
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2001 թուականի Մարտին հրատարակուած գիտական յօդուած
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2001 թվականի մարտին հրատարակված գիտական հոդված
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2001年の論文
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2001年学术文章
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2001年学术文章
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2001年学术文章
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2001年学术文章
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2001年學術文章
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name
Roles of the forkhead in rhabd ...... ivation and nuclear targetting
@ast
Roles of the forkhead in rhabd ...... ivation and nuclear targetting
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Roles of the forkhead in rhabd ...... ivation and nuclear targetting
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Roles of the forkhead in rhabd ...... ivation and nuclear targetting
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Roles of the forkhead in rhabd ...... ivation and nuclear targetting
@ast
Roles of the forkhead in rhabd ...... ivation and nuclear targetting
@en
Roles of the forkhead in rhabd ...... ivation and nuclear targetting
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Roles of the forkhead in rhabd ...... ivation and nuclear targetting
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prefLabel
Roles of the forkhead in rhabd ...... ivation and nuclear targetting
@ast
Roles of the forkhead in rhabd ...... ivation and nuclear targetting
@en
Roles of the forkhead in rhabd ...... ivation and nuclear targetting
@en-gb
Roles of the forkhead in rhabd ...... ivation and nuclear targetting
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Roles of the forkhead in rhabd ...... ivation and nuclear targetting
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10.1042/0264-6021:3540605
10.1042/BJ3540605
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P577
2001-03-15T00:00:00Z