The kinase DYRK1A phosphorylates the transcription factor FKHR at Ser329 in vitro, a novel in vivo phosphorylation site
about
Genome-wide association study identifies single nucleotide polymorphism in DYRK1A associated with replication of HIV-1 in monocyte-derived macrophagesThe kinase DYRK phosphorylates protein-synthesis initiation factor eIF2Bepsilon at Ser539 and the microtubule-associated protein tau at Thr212: potential role for DYRK as a glycogen synthase kinase 3-priming kinaseDYRK1A autophosphorylation on serine residue 520 modulates its kinase activity via 14-3-3 bindingSuppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylationDirect association of Sprouty-related protein with an EVH1 domain (SPRED) 1 or SPRED2 with DYRK1A modifies substrate/kinase interactionsIdentification of Protor as a novel Rictor-binding component of mTOR complex-2The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+-Cl- co-transportersCDK1 promotes cell proliferation and survival via phosphorylation and inhibition of FOXO1 transcription factordDYRK2: a novel dual-specificity tyrosine-phosphorylation-regulated kinase in DrosophilaHeat-shock protein 90 and Cdc37 interact with LKB1 and regulate its stabilityTwo novel phosphorylation sites on FKHR that are critical for its nuclear exclusionThe highly related DEAD box RNA helicases p68 and p72 exist as heterodimers in cellsExpression of Drosophila FOXO regulates growth and can phenocopy starvationOverexpression of the human MNB/DYRK1A gene induces formation of multinucleate cells through overduplication of the centrosomeDYRK1A, a Dosage-Sensitive Gene Involved in Neurodevelopmental Disorders, Is a Target for Drug Development in Down SyndromeRedox regulation of FoxO transcription factorsAkt signaling dynamics in individual cells.FoxO6 transcriptional activity is regulated by Thr26 and Ser184, independent of nucleo-cytoplasmic shuttlingIdentification of the autophosphorylation sites and characterization of their effects in the protein kinase DYRK1ADyrk1A potentiates steroid hormone-induced transcription via the chromatin remodeling factor Arip4DYRK1A enhances the mitogen-activated protein kinase cascade in PC12 cells by forming a complex with Ras, B-Raf, and MEK1.The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinasesDyrk1A haploinsufficiency affects viability and causes developmental delay and abnormal brain morphology in miceTransgenic mouse in vivo library of human Down syndrome critical region 1: association between DYRK1A overexpression, brain development abnormalities, and cell cycle protein alteration.The protein kinase DYRK1A phosphorylates the splicing factor SF3b1/SAP155 at Thr434, a novel in vivo phosphorylation siteRNAi screening for kinases and phosphatases identifies FoxO regulatorsIdentification and analysis of evolutionary selection pressures acting at the molecular level in five forkhead subfamilies.Green tea polyphenols rescue of brain defects induced by overexpression of DYRK1A.Phosphorylation and acetylation modifications of FOXO3a: Independently or synergistically?The protein kinase MBK-1 contributes to lifespan extension in daf-2 mutant and germline-deficient Caenorhabditis elegans.Insulin signaling, resistance, and the metabolic syndrome: insights from mouse models into disease mechanisms.The FoxO family in cardiac function and dysfunction.FOXO1: a potential target for human diseasesFoxO, autophagy, and cardiac remodeling.Black tea polyphenols mimic insulin/insulin-like growth factor-1 signalling to the longevity factor FOXO1a.The role of mirk kinase in sarcomasThe human T-cell leukemia virus type 1 oncoprotein tax controls forkhead box O4 activity through degradation by the proteasomeInsulin and LiCl synergistically rescue myogenic differentiation of FoxO1 over-expressed myoblastsDecisions on life and death: FOXO Forkhead transcription factors are in command when PKB/Akt is off duty.Deciphering the role of forkhead transcription factors in cancer therapy
P2860
Q21135536-36AEFD2E-913B-4BB2-9057-1F7EA97B4929Q24291138-8DDCF601-B2D2-49EB-9AB9-D5550C6860CCQ24293338-A4573243-C41A-4929-B5F6-AD5C111D1149Q24293737-83278F7D-ADEF-42FC-A641-C88471059C84Q24297221-61C52523-FA67-4DD1-9364-6ED689707D3CQ24303936-B4DBB04B-C8C9-4EA3-A22B-DE1E2575B6CEQ24317496-C3E2657F-D1DC-4A44-9DFB-C4D719827817Q24321230-7DE3D9F3-FAEF-4261-85CD-DA54100E0F62Q24530188-CCA0D0B5-E704-42A9-8B66-55E09C2EB67CQ24535623-2877CB99-73C1-45E9-902A-43B9A0CA3A33Q24536290-730705D0-3738-453A-B048-930076AE2FCEQ24550717-08FE4FD4-653C-4054-8D7E-8DB6D3597FECQ24794099-2F5E2ECB-0363-4C64-AC55-CB98B5374963Q24803124-B26C6F35-6389-4440-A105-27E23D92CEC6Q26745413-C8E760F6-EB88-4574-A462-5BBA5952BE16Q26799843-5E1C0E73-D7E1-42AD-85BC-F7DE68D22B58Q27340143-56A89820-8BED-4FF1-99A3-D02D0680730AQ28258996-80680D7C-7EDC-4C73-9782-FE8C674824AFQ28362375-8DFF6C62-0586-4142-854E-BE51F9326060Q28510482-2252902C-1F42-469C-951D-8B9F7BE43C85Q28574593-4AAA8E28-E0A9-4834-87A1-C615468A5B45Q28583124-F40BD856-2BF6-49AB-ACD9-17C98B6DC590Q30531707-0FE15844-BB64-4C8C-AFF3-8C092241F80EQ31079724-DADBAE71-D7DD-4010-81F8-672C7345349FQ33235281-2399FC4E-BB54-4584-A481-02700E92721AQ33371685-6AF6416F-02CB-4066-8269-BDE3E33AB8B4Q33371818-A1182215-7955-4DFD-9E51-6EC2FBBDD797Q33412381-93D92154-FAE4-409C-ADE9-58CF79064049Q33685068-DD71F9B0-08F0-4F91-A2CE-8BBF1BCD940EQ33804604-0B5733B8-89C6-4BFE-9D71-06C017CDBD7EQ33865096-BA49549F-2DD5-4B1C-933C-84BCEF67AF52Q34013124-BBC05215-8AC0-43D1-AF28-AE7325E9B5D2Q34173809-C90F793C-3E43-49EF-BDEF-FFA9AC704EC0Q34362813-B777FFA6-D59D-4E47-898E-89352AC19076Q34713913-AA8780DA-0F05-47D6-98B8-348DCE36E8FEQ34928886-9F9A5021-D5B5-4B32-B3E5-5AC14514AA02Q35077555-BB55678F-C5AF-44FA-B6E5-79EE2974AC08Q35097402-B4714C4B-F30F-47D7-B5B5-56E62835B5F1Q35139549-FC1D4A23-F485-4A0B-BEB7-378A5DE1A281Q35146638-CF53B765-CC98-4B4E-BBE3-1B7915EEB419
P2860
The kinase DYRK1A phosphorylates the transcription factor FKHR at Ser329 in vitro, a novel in vivo phosphorylation site
description
2001 nî lūn-bûn
@nan
2001 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
name
The kinase DYRK1A phosphorylat ...... l in vivo phosphorylation site
@ast
The kinase DYRK1A phosphorylat ...... l in vivo phosphorylation site
@en
The kinase DYRK1A phosphorylat ...... l in vivo phosphorylation site
@en-gb
The kinase DYRK1A phosphorylat ...... l in vivo phosphorylation site
@nl
type
label
The kinase DYRK1A phosphorylat ...... l in vivo phosphorylation site
@ast
The kinase DYRK1A phosphorylat ...... l in vivo phosphorylation site
@en
The kinase DYRK1A phosphorylat ...... l in vivo phosphorylation site
@en-gb
The kinase DYRK1A phosphorylat ...... l in vivo phosphorylation site
@nl
prefLabel
The kinase DYRK1A phosphorylat ...... l in vivo phosphorylation site
@ast
The kinase DYRK1A phosphorylat ...... l in vivo phosphorylation site
@en
The kinase DYRK1A phosphorylat ...... l in vivo phosphorylation site
@en-gb
The kinase DYRK1A phosphorylat ...... l in vivo phosphorylation site
@nl
P2093
P2860
P3181
P356
P1433
P1476
The kinase DYRK1A phosphorylat ...... l in vivo phosphorylation site
@en
P2093
T G Unterman
P2860
P304
P3181
P356
10.1042/BJ3550597
P407
P577
2001-05-01T00:00:00Z