Polycystin-2, the protein mutated in autosomal dominant polycystic kidney disease (ADPKD), is a Ca2+-permeable nonselective cation channel
about
A method for measuring electrical signals in a primary ciliumTrafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulationA polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexesAlpha-actinin associates with polycystin-2 and regulates its channel activityMutations in Mcoln3 associated with deafness and pigmentation defects in varitint-waddler (Va) mice.Role of calcium in polycystic kidney disease: From signaling to pathologyA polycystin-centric view of cyst formation and disease: the polycystins revisitedMicroRNAs in the pathogenesis of cystic kidney diseasePermeation, regulation and control of expression of TRP channels by trace metal ionsWnt and planar cell polarity signaling in cystic renal diseaseNovel role of ouabain as a cystogenic factor in autosomal dominant polycystic kidney diseasePolycystin-1 cleavage and the regulation of transcriptional pathwaysSwelling-activated Ca2+ channels trigger Ca2+ signals in Merkel cellsPkd1 and Pkd2 are required for normal placental developmentThe exocyst protein Sec10 interacts with Polycystin-2 and knockdown causes PKD-phenotypesStructural and molecular basis of the assembly of the TRPP2/PKD1 complexMolecular mechanism of the assembly of an acid-sensing receptor ion channel complex.A conserved signal and GTPase complex are required for the ciliary transport of polycystin-1.Regulation of calcium signaling by polycystin-2Thick ascending limb: the Na(+):K (+):2Cl (-) co-transporter, NKCC2, and the calcium-sensing receptor, CaSRCharacterization of the maitotoxin-activated cationic current from human skin fibroblastsRegulation of ryanodine receptor-dependent calcium signaling by polycystin-2Loss of polycystin-1 or polycystin-2 results in dysregulated apolipoprotein expression in murine tissues via alterations in nuclear hormone receptorsPkd1l1 establishes left-right asymmetry and physically interacts with Pkd2.TAZ promotes PC2 degradation through a SCFbeta-Trcp E3 ligase complexNative polycystin 2 functions as a plasma membrane Ca2+-permeable cation channel in renal epitheliaTransient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptorThe native TRPP2-dependent channel of murine renal primary ciliaFunction and regulation of TRPP2 ion channel revealed by a gain-of-function mutantThe cAMP Signaling Pathway and Direct Protein Kinase A Phosphorylation Regulate Polycystin-2 (TRPP2) Channel FunctionTRP channelsPhylogeny as a guide to structure and function of membrane transport proteins.Situs inversus and ciliary abnormalities: 20 years later, what is the connection?Domain mapping of the polycystin-2 C-terminal tail using de novo molecular modeling and biophysical analysis.Mutant polycystin-2 induces proliferation in primary rat tubular epithelial cells in a STAT-1/p21-independent fashion accompanied instead by alterations in expression of p57KIP2 and Cdk2.Naringenin inhibits the growth of Dictyostelium and MDCK-derived cysts in a TRPP2 (polycystin-2)-dependent manner.TRPV4 mediates flow-induced increases in intracellular Ca in medullary thick ascending limbs.The role of noise and positive feedback in the onset of autosomal dominant diseases.Spatially resolved shear distribution in microfluidic chip for studying force transduction mechanisms in cells.Polycystic kidney disease.
P2860
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P2860
Polycystin-2, the protein mutated in autosomal dominant polycystic kidney disease (ADPKD), is a Ca2+-permeable nonselective cation channel
description
2001 nî lūn-bûn
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2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2001 թվականի հունվարին հրատարակված գիտական հոդված
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name
Polycystin-2, the protein muta ...... le nonselective cation channel
@ast
Polycystin-2, the protein muta ...... le nonselective cation channel
@en
Polycystin-2, the protein muta ...... le nonselective cation channel
@en-gb
Polycystin-2, the protein muta ...... le nonselective cation channel
@nl
type
label
Polycystin-2, the protein muta ...... le nonselective cation channel
@ast
Polycystin-2, the protein muta ...... le nonselective cation channel
@en
Polycystin-2, the protein muta ...... le nonselective cation channel
@en-gb
Polycystin-2, the protein muta ...... le nonselective cation channel
@nl
prefLabel
Polycystin-2, the protein muta ...... le nonselective cation channel
@ast
Polycystin-2, the protein muta ...... le nonselective cation channel
@en
Polycystin-2, the protein muta ...... le nonselective cation channel
@en-gb
Polycystin-2, the protein muta ...... le nonselective cation channel
@nl
P2093
P2860
P921
P356
P1476
Polycystin-2, the protein muta ...... le nonselective cation channel
@en
P2093
A E Damiano
H F Cantiello
I L Reisin
M A Arnaout
P C Harris
S González-Perrett
P2860
P304
P356
10.1073/PNAS.98.3.1182
P407
P577
2001-01-30T00:00:00Z