Crystal structure of the 14-3-3zeta:serotonin N-acetyltransferase complex. a role for scaffolding in enzyme regulation
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Structural Analysis of the 14-3-3ζ/Chibby Interaction Involved in Wnt/β-Catenin SignalingCrystal structure and functional mapping of human ASMT, the last enzyme of the melatonin synthesis pathwayDYRK1A autophosphorylation on serine residue 520 modulates its kinase activity via 14-3-3 bindingImpaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling14-3-3 amplifies and prolongs adrenergic stimulation of HERG K+ channel activityThe regulated assembly of a PKCepsilon complex controls the completion of cytokinesisDifferential 14-3-3 affinity capture reveals new downstream targets of phosphatidylinositol 3-kinase signalingRecognition of an intra-chain tandem 14-3-3 binding site within PKCepsilonProtein kinase A-mediated 14-3-3 association impedes human Dapper1 to promote dishevelled degradationInteraction with 14-3-3 proteins promotes functional expression of the potassium channels TASK-1 and TASK-3Analysis of serotonin N-acetyltransferase regulation in vitro and in live cells using protein semisynthesisDe novo discovery of serotonin N-acetyltransferase inhibitors14-3-3s regulate fructose-2,6-bisphosphate levels by binding to PKB-phosphorylated cardiac fructose-2,6-bisphosphate kinase/phosphataseStructure and Functional Diversity of GCN5-Related N-Acetyltransferases (GNAT)Potential prognostic, diagnostic and therapeutic markers for human gastric cancerInvestigation of the roles of catalytic residues in serotonin N-acetyltransferaseStructural view of a fungal toxin acting on a 14-3-3 regulatory complexPhosphorylation-independent interaction between 14-3-3 and exoenzyme S: from structure to pathogenesisStructure of a 14-3-3σ–YAP phosphopeptide complex at 1.15 Å resolutionDiscovery and structural characterization of a small molecule 14-3-3 protein-protein interaction inhibitorCharacterization of 14-3-3-ζ Interactions with Integrin TailsThe N-Terminal Sequence of Tyrosine Hydroxylase Is a Conformationally Versatile Motif That Binds 14-3-3 Proteins and MembranesCrystal structure of the dopamine N -acetyltransferase–acetyl-CoA complex provides insights into the catalytic mechanismCharacterization of the Saccharomyces cerevisiae homolog of the melatonin rhythm enzyme arylalkylamine N-acetyltransferase (EC 2.3.1.87).Self-association of the spindle pole body-related intermediate filament protein Fin1p and its phosphorylation-dependent interaction with 14-3-3 proteins in yeast.Regulation of yeast Yak1 kinase by PKA and autophosphorylation-dependent 14-3-3 binding.Role of the 14-3-3 C-terminal loop in ligand interactionAn intramolecular disulfide bridge as a catalytic switch for serotonin N-acetyltransferaseThe serine-rich domain from Crk-associated substrate (p130cas) is a four-helix bundleThree-way interaction between 14-3-3 proteins, the N-terminal region of tyrosine hydroxylase, and negatively charged membranes14-3-3 isoforms bind directly exon B of the 5'-UTR of human surfactant protein A2 mRNA14-3-3 zeta as novel molecular target for cancer therapyBoth the N-terminal loop and wing W2 of the forkhead domain of transcription factor Foxo4 are important for DNA bindingPhospho-Ser/Thr-binding domains: navigating the cell cycle and DNA damage responseThe weak complex between RhoGAP protein ARHGAP22 and signal regulatory protein 14-3-3 has 1:2 stoichiometry and a single peptide binding modeForkhead-associated domain-containing protein Rv0019c and polyketide-associated protein PapA5, from substrates of serine/threonine protein kinase PknB to interacting proteins of Mycobacterium tuberculosisRole of a pineal cAMP-operated arylalkylamine N-acetyltransferase/14-3-3-binding switch in melatonin synthesisRhythmic control of AANAT translation by hnRNP Q in circadian melatonin productionIdentification of the amino acids 300-600 of IRS-2 as 14-3-3 binding region with the importance of IGF-1/insulin-regulated phosphorylation of Ser-573Cannabinoids attenuate norepinephrine-induced melatonin biosynthesis in the rat pineal gland by reducing arylalkylamine N-acetyltransferase activity without involvement of cannabinoid receptors
P2860
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P2860
Crystal structure of the 14-3-3zeta:serotonin N-acetyltransferase complex. a role for scaffolding in enzyme regulation
description
2001 nî lūn-bûn
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2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի ապրիլին հրատարակված գիտական հոդված
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2001年の論文
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2001年学术文章
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2001年学术文章
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2001年学术文章
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2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
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name
Crystal structure of the 14-3- ...... affolding in enzyme regulation
@ast
Crystal structure of the 14-3- ...... affolding in enzyme regulation
@en
Crystal structure of the 14-3- ...... affolding in enzyme regulation
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Crystal structure of the 14-3- ...... affolding in enzyme regulation
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label
Crystal structure of the 14-3- ...... affolding in enzyme regulation
@ast
Crystal structure of the 14-3- ...... affolding in enzyme regulation
@en
Crystal structure of the 14-3- ...... affolding in enzyme regulation
@en-gb
Crystal structure of the 14-3- ...... affolding in enzyme regulation
@nl
prefLabel
Crystal structure of the 14-3- ...... affolding in enzyme regulation
@ast
Crystal structure of the 14-3- ...... affolding in enzyme regulation
@en
Crystal structure of the 14-3- ...... affolding in enzyme regulation
@en-gb
Crystal structure of the 14-3- ...... affolding in enzyme regulation
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P2093
P3181
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Crystal structure of the 14-3- ...... affolding in enzyme regulation
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P2093
P304
P3181
P356
10.1016/S0092-8674(01)00316-6
P407
P577
2001-04-20T00:00:00Z