14-3-3 zeta as novel molecular target for cancer therapy
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Structural Analysis of the 14-3-3ζ/Chibby Interaction Involved in Wnt/β-Catenin SignalingMetabolic-stress-induced rearrangement of the 14-3-3ζ interactome promotes autophagy via a ULK1- and AMPK-regulated 14-3-3ζ interaction with phosphorylated Atg9Establishing a novel knock-in mouse line for studying neuronal cytoplasmic dynein under normal and pathologic conditionsA microarray-based gene expression analysis to identify diagnostic biomarkers for unknown primary cancerGenome-Wide and Experimental Resolution of Relative Translation Elongation Speed at Individual Gene Level in Human CellsDeep-proteome mapping of WM-266-4 human metastatic melanoma cells: From oncogenic addiction to druggable targetsTipping the balance between good and evil: aberrant 14-3-3ζ expression drives oncogenic TGF-β signaling in metastatic breast cancersmiR-451 regulates FoxO3 nuclear accumulation through Ywhaz in human colorectal cancerBcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity.Coexistence of YWHAZ amplification predicts better prognosis in muscle-invasive bladder cancer with CDKN2A or TP53 loss.14-3-3ζ and aPKC-ι synergistically facilitate epithelial-mesenchymal transition of cholangiocarcinoma via GSK-3β/Snail signaling pathway.14-3-3ζ/TGFβR1 promotes tumor metastasis in lung squamous cell carcinoma.Wnt5a induces ROR1 to associate with 14-3-3ζ for enhanced chemotaxis and proliferation of chronic lymphocytic leukemia cells.Identification of 14-3-3zeta associated protein networks in oral cancer.Histone deacetylase 6 (HDAC6) promotes the pro-survival activity of 14-3-3ζ via deacetylation of lysines within the 14-3-3ζ binding pocket.Tanshinone IIA inhibits the proliferation, migration and invasion of ectopic endometrial stromal cells of adenomyosis via 14-3-3ζ downregulation.14-3-3ζ loss impedes oncogene-induced mammary tumorigenesis and metastasis by attenuating oncogenic signaling.Identification of a novel YAP-14-3-3ζ negative feedback loop in gastric cancer.The overexpression of 14-3-3ζ and Hsp27 promotes non–small cell lung cancer progression.The phytotoxin fusicoccin, a selective stabilizer of 14-3-3 interactions?14-3-3ζ loss leads to neonatal lethality by microRNA-126 downregulation-mediated developmental defects in lung vasculature.Differential Proteome Analysis of Extracellular Vesicles from Breast Cancer Cell Lines by Chaperone Affinity Enrichment.Optimal reference genes for RT-qPCR normalization in the newborn.Chk1 and 14-3-3 proteins inhibit atypical E2Fs to prevent a permanent cell cycle arrest.Suppression of 14-3-3ζ in cholangiocarcinoma cells inhibits proliferation through attenuated Akt activity, enhancing chemosensitivity to gemcitabine.The phytotoxin fusicoccin differently regulates 14-3-3 proteins association to mode III targets.An integrated approach to infer cross-talks between intracellular protein transport and signaling pathways.Knockdown of tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta (YWHAZ) enhances tumorigenesis both in vivo and in vitro in bladder cancer.Involvement of multiple cellular pathways in regulating resistance to tamoxifen in BIK-suppressed MCF-7 cells.14-3-3ζ silencing retards tongue squamous cell carcinoma progression by inhibiting cell survival and migration.Prognostic significance of YWHAZ expression in localized prostate cancer.The ASH1-miR-375-YWHAZ Signaling Axis Regulates Tumor Properties in Hepatocellular Carcinoma.Molecular Cloning and Effects of -Silencing on Larval Survivability Against and inMicroRNA-375 Suppresses the Tumor Aggressive Phenotypes of Clear Cell Renal Cell Carcinomas through Regulating YWHAZ
P2860
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P2860
14-3-3 zeta as novel molecular target for cancer therapy
description
2012 nî lūn-bûn
@nan
2012 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
14-3-3 zeta as novel molecular target for cancer therapy
@ast
14-3-3 zeta as novel molecular target for cancer therapy
@en
14-3-3 zeta as novel molecular target for cancer therapy
@nl
type
label
14-3-3 zeta as novel molecular target for cancer therapy
@ast
14-3-3 zeta as novel molecular target for cancer therapy
@en
14-3-3 zeta as novel molecular target for cancer therapy
@nl
prefLabel
14-3-3 zeta as novel molecular target for cancer therapy
@ast
14-3-3 zeta as novel molecular target for cancer therapy
@en
14-3-3 zeta as novel molecular target for cancer therapy
@nl
P2093
P2860
P3181
P1476
14-3-3 zeta as novel molecular target for cancer therapy
@en
P2093
Ajay Matta
K W Michael Siu
Ranju Ralhan
P2860
P304
P3181
P356
10.1517/14728222.2012.668185
P407
P577
2012-05-01T00:00:00Z