Reactive oxygen species-induced phosphorylation of p53 on serine 20 is mediated in part by polo-like kinase-3
about
Pyruvate dehydrogenase kinase as a novel therapeutic target in oncologyPlk3 functions as an essential component of the hypoxia regulatory pathway by direct phosphorylation of HIF-1alphaPolo box domain of Plk3 functions as a centrosome localization signal, overexpression of which causes mitotic arrest, cytokinesis defects, and apoptosisPlk3 interacts with and specifically phosphorylates VRK1 in Ser342, a downstream target in a pathway that induces Golgi fragmentationCalcium-dependent inhibition of polo-like kinase 3 activity by CIB1 in breast cancer cellsPlk5, a polo box domain-only protein with specific roles in neuron differentiation and glioblastoma suppressionThe in vivo gene expression signature of oxidative stressPutting a bit into the polo-box domain of polo-like kinase 1Hydrogen peroxide sensing, signaling and regulation of transcription factorsNADPH oxidases: key modulators in aging and age-related cardiovascular diseases?Mammalian Polo-like kinase 3 (Plk3) is a multifunctional protein involved in stress response pathwaysA genome-wide RNAi screen reveals multiple regulators of caspase activationAnti-cancer activity of a novel small molecule compound that simultaneously activates p53 and inhibits NF-κB signalingRegulation of PTEN stability and activity by Plk3Folate MetabolismPolo-like kinase 1 (Plk1) inhibits p53 function by physical interaction and phosphorylation.Combination of NTP with cetuximab inhibited invasion/migration of cetuximab-resistant OSCC cells: Involvement of NF-κB signaling.Polo-box domain: a versatile mediator of polo-like kinase function.Prostaglandin (PG)D(2) and 15-deoxy-Delta(12,14)-PGJ(2), but not PGE(2), mediate shear-induced chondrocyte apoptosis via protein kinase A-dependent regulation of polo-like kinasesPolo-like kinase 2 activates an antioxidant pathway to promote the survival of cells with mitochondrial dysfunction.Chk2-deficient mice exhibit radioresistance and defective p53-mediated transcriptionOsmotic stress-induced phosphorylation of H2AX by polo-like kinase 3 affects cell cycle progression in human corneal epithelial cellsA natural small molecule harmine inhibits angiogenesis and suppresses tumour growth through activation of p53 in endothelial cells.Several dual specificity phosphatases coordinate to control the magnitude and duration of JNK activation in signaling response to oxidative stress.Effect of hypoxic stress-activated Polo-like kinase 3 on corneal epithelial wound healingPolo-like kinases and centrosome regulation.Dysregulation of the polo-like kinase pathway in CD4+ T cells is characteristic of pathogenic simian immunodeficiency virus infection.Mechanism of Cisplatin-Induced Cytotoxicity Is Correlated to Impaired Metabolism Due to Mitochondrial ROS Generation.TGRL Lipolysis Products Induce Stress Protein ATF3 via the TGF-β Receptor Pathway in Human Aortic Endothelial CellsPathway-specific effect of caffeine on protection against UV irradiation-induced apoptosis in corneal epithelial cells.Polo-like kinases in the nervous system.Stress-induced corneal epithelial apoptosis mediated by K+ channel activationMetabolic regulation of oxygen and redox homeostasis by p53: lessons from evolutionary biology?Recent Advances and New Strategies in Targeting Plk1 for Anticancer TherapyThe absence of Ser389 phosphorylation in p53 affects the basal gene expression level of many p53-dependent genes and alters the biphasic response to UV exposure in mouse embryonic fibroblasts.APE2 is required for ATR-Chk1 checkpoint activation in response to oxidative stress.Polo-like kinase 3 functions as a tumor suppressor and is a negative regulator of hypoxia-inducible factor-1 alpha under hypoxic conditions.Defective apoptosis and B-cell lymphomas in mice with p53 point mutation at Ser 23.Aldose reductase-mediated phosphorylation of p53 leads to mitochondrial dysfunction and damage in diabetic platelets.p53: the attractive tumor suppressor in the cancer research field.
P2860
Q21129303-13B07E62-D66B-4F83-BD16-0D346D2A59C6Q24301526-134F4D54-BDC5-4AC3-A000-FBDA1D996402Q24304476-1E3E4A3B-A0CB-4FAC-AE41-5A7DA835EF03Q24310419-685D9CB0-94E1-4335-AB2E-E37ADC86A7B3Q24313054-454870D9-B16A-4C4E-A424-30DA8C77F860Q24337639-25DD1202-0F9A-4492-BEB5-EAFC7C2C58F7Q24653033-195358FB-F1A6-4DC5-AB41-3543BE34DB09Q26779135-C237D3FC-C020-44BA-AA99-AE6909433464Q27004438-104CDE05-102D-499C-A70B-BAB5552AC811Q28072348-220ECACE-F302-45BC-829F-113C48F158A9Q28202838-2E16B6B4-4C1F-451B-B201-1420F08F1ADFQ28257071-33385E35-57EA-478A-BA3B-E9489DE85C51Q28483751-AA449275-EB45-4427-8497-1C10161C77AFQ28512686-E09EA2AD-60B3-490D-9A7B-D7D666D3ED9BQ30225387-2AEB62FD-5542-4B40-B014-46A18A2F19FEQ33199646-2B581A1B-1B77-4E38-B7A4-D212D030D677Q33466722-A9568A42-F863-4F3A-839D-8E5F36AE7172Q33882148-DCFB4B03-FE87-4DEF-B1A3-DC5B9E51E58CQ33926052-FE8B1B35-757C-4FFE-9201-E5847DA3565CQ33970870-2A7C6506-A4BA-4C54-8166-927B5B94FC63Q34149479-84981864-169E-4995-B65D-09AFD6D89E3FQ34396857-27F1AF00-C87B-4FDA-B0F9-2E1A0F0537F6Q34540424-B2DCF114-4ACE-4D89-A04E-2A9516D23AE5Q34660270-19B24772-1F9F-4EB4-8B6C-1DE87E262C0EQ34735346-B4C1F031-4574-4A11-AB24-619ADB911290Q34818259-A8764E53-CB71-4609-AD4E-1353C7659E5CQ35542632-58873BFD-A3B2-48F1-8603-BC820DED7A2BQ35738714-6B326967-8B68-44F2-8A1D-FE356F8650D4Q35879314-23ED8E9B-8BCD-4A1B-8DD2-C977163B482EQ35894504-A02888E0-022B-4587-89CD-BFF8F4D5D2F6Q36004655-BE6CC1DA-09A4-43A8-AD68-272A5B77B726Q36015695-2F54DC70-1D1B-45C9-97F6-29ACB9D755A8Q36239686-53FBB49D-173D-4CA8-BEF4-67B73472C8BCQ36386336-478D093E-A615-464F-A286-90A5AAA8F307Q36497975-CAA3F5A2-22A8-4999-B81B-DCC5AEDEFEE0Q36967831-A3CC75D6-78F0-4EDF-BC63-5892D53F1575Q37051199-4CE40C5A-4F97-4C46-98F0-C6301B2F3754Q37524264-C9042C39-5DBA-4A0B-B95D-E03337CDCA8AQ37707000-813B3243-CC3C-48F3-A488-2E40FDFC85BBQ37824262-86683131-2806-4615-9FFA-B96F12279EA2
P2860
Reactive oxygen species-induced phosphorylation of p53 on serine 20 is mediated in part by polo-like kinase-3
description
2001 nî lūn-bûn
@nan
2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Reactive oxygen species-induce ...... in part by polo-like kinase-3
@ast
Reactive oxygen species-induce ...... in part by polo-like kinase-3
@en
Reactive oxygen species-induce ...... in part by polo-like kinase-3
@en-gb
Reactive oxygen species-induce ...... in part by polo-like kinase-3
@nl
type
label
Reactive oxygen species-induce ...... in part by polo-like kinase-3
@ast
Reactive oxygen species-induce ...... in part by polo-like kinase-3
@en
Reactive oxygen species-induce ...... in part by polo-like kinase-3
@en-gb
Reactive oxygen species-induce ...... in part by polo-like kinase-3
@nl
prefLabel
Reactive oxygen species-induce ...... in part by polo-like kinase-3
@ast
Reactive oxygen species-induce ...... in part by polo-like kinase-3
@en
Reactive oxygen species-induce ...... in part by polo-like kinase-3
@en-gb
Reactive oxygen species-induce ...... in part by polo-like kinase-3
@nl
P2093
P2860
P921
P356
P1476
Reactive oxygen species-induce ...... in part by polo-like kinase-3
@en
P2093
J Cogswell
M Jhanwar-Uniyal
P2860
P304
P356
10.1074/JBC.M104157200
P407
P577
2001-09-28T00:00:00Z