The TRAP/Mediator coactivator complex interacts directly with estrogen receptors alpha and beta through the TRAP220 subunit and directly enhances estrogen receptor function in vitro
about
The Mediator subunit MED1/TRAP220 is required for optimal glucocorticoid receptor-mediated transcription activationHuman Ccr4-Not complex is a ligand-dependent repressor of nuclear receptor-mediated transcriptionActivation of TRAP/mediator subunit TRAP220/Med1 is regulated by mitogen-activated protein kinase-dependent phosphorylationComponents of the CCR4-NOT complex function as nuclear hormone receptor coactivators via association with the NRC-interacting Factor NIF-1A coregulatory role for the TRAP-mediator complex in androgen receptor-mediated gene expressionIdentification of the MLL2 complex as a coactivator for estrogen receptor alphaCCAR1, a key regulator of mediator complex recruitment to nuclear receptor transcription complexesA positive feedback loop links circadian clock factor CLOCK-BMAL1 to the basic transcriptional machineryIdentification of a transcriptionally active peroxisome proliferator-activated receptor alpha -interacting cofactor complex in rat liver and characterization of PRIC285 as a coactivator.Role of metazoan mediator proteins in interferon-responsive transcriptionA novel docking site on Mediator is critical for activation by VP16 in mammalian cellsArginine and glutamate-rich 1 (ARGLU1) interacts with mediator subunit 1 (MED1) and is required for estrogen receptor-mediated gene transcription and breast cancer cell growthAdvances in estrogen receptor biology: prospects for improvements in targeted breast cancer therapyMediator-dependent nuclear receptor functionAn hGCN5/TRRAP histone acetyltransferase complex co-activates BRCA1 transactivation function through histone modificationT:G mismatch-specific thymine-DNA glycosylase potentiates transcription of estrogen-regulated genes through direct interaction with estrogen receptor alphaTIP30 interacts with an estrogen receptor alpha-interacting coactivator CIA and regulates c-myc transcriptionMED12 somatic mutations in fibroadenomas and phyllodes tumours of the breastAn Oct4-centered protein interaction network in embryonic stem cellsThe Mediator complex and transcription regulationKey roles for MED1 LxxLL motifs in pubertal mammary gland development and luminal-cell differentiationStructural and functional organization of TRAP220, the TRAP/mediator subunit that is targeted by nuclear receptorsERR-10: a new repressor in transcriptional signaling activation of estrogen receptor-alpha.Mediator and human diseaseCross-talk between HER2 and MED1 regulates tamoxifen resistance of human breast cancer cells.Coactivators in PPAR-Regulated Gene ExpressionExome sequencing identifies highly recurrent MED12 somatic mutations in breast fibroadenoma.Mediator and p300/CBP-steroid receptor coactivator complexes have distinct roles, but function synergistically, during estrogen receptor alpha-dependent transcription with chromatin templates.Chromatin exposes intrinsic differences in the transcriptional activities of estrogen receptors alpha and beta.Gender difference in the activity but not expression of estrogen receptors alpha and beta in human lung adenocarcinoma cells.Proteomic analysis of coregulators bound to ERα on DNA and nucleosomes reveals coregulator dynamics.Silencing MED1 sensitizes breast cancer cells to pure anti-estrogen fulvestrant in vitro and in vivo.Med25 is required for estrogen receptor alpha (ERα)-mediated regulation of human CYP2C9 expression.Proteomic analysis of the herpes simplex virus 1 virion protein 16 transactivator protein in infected cellsMED30 Regulates the Proliferation and Motility of Gastric Cancer Cells.A single-nucleotide polymorphism in a half-binding site creates p53 and estrogen receptor control of vascular endothelial growth factor receptor 1.Med1 plays a critical role in the development of tamoxifen resistance.Coactivation of estrogen receptor alpha (ER alpha)/Sp1 by vitamin D receptor interacting protein 150 (DRIP150).Suppression of Adipocyte Differentiation by Foenumoside B from Lysimachia foenum-graecum Is Mediated by PPARγ AntagonismLeiomyoma: genetics, assisted reproduction, pregnancy and therapeutic advances
P2860
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P248
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P2860
The TRAP/Mediator coactivator complex interacts directly with estrogen receptors alpha and beta through the TRAP220 subunit and directly enhances estrogen receptor function in vitro
description
2002 nî lūn-bûn
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2002 թուականի Մարտին հրատարակուած գիտական յօդուած
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2002 թվականի մարտին հրատարակված գիտական հոդված
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2002年の論文
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2002年論文
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2002年論文
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2002年論文
@zh-hk
2002年論文
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2002年論文
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2002年论文
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name
The TRAP/Mediator coactivator ...... gen receptor function in vitro
@ast
The TRAP/Mediator coactivator ...... gen receptor function in vitro
@en
The TRAP/Mediator coactivator ...... gen receptor function in vitro
@en-gb
The TRAP/Mediator coactivator ...... gen receptor function in vitro
@nl
type
label
The TRAP/Mediator coactivator ...... gen receptor function in vitro
@ast
The TRAP/Mediator coactivator ...... gen receptor function in vitro
@en
The TRAP/Mediator coactivator ...... gen receptor function in vitro
@en-gb
The TRAP/Mediator coactivator ...... gen receptor function in vitro
@nl
prefLabel
The TRAP/Mediator coactivator ...... gen receptor function in vitro
@ast
The TRAP/Mediator coactivator ...... gen receptor function in vitro
@en
The TRAP/Mediator coactivator ...... gen receptor function in vitro
@en-gb
The TRAP/Mediator coactivator ...... gen receptor function in vitro
@nl
P2093
P2860
P3181
P356
P1476
The TRAP/Mediator coactivator ...... gen receptor function in vitro
@en
P2093
Chao-Xing Yuan
Mohamed Guermah
Robert G Roeder
Yun Kyoung Kang
P2860
P304
P3181
P356
10.1073/PNAS.261715899
P407
P577
2002-03-05T00:00:00Z