A novel docking site on Mediator is critical for activation by VP16 in mammalian cells
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Mediator modulates Gli3-dependent Sonic hedgehog signalingMED25 is distinct from TRAP220/MED1 in cooperating with CBP for retinoid receptor activationPTOV1 enables the nuclear translocation and mitogenic activity of flotillin-1, a major protein of lipid raftsMED19 and MED26 are synergistic functional targets of the RE1 silencing transcription factor in epigenetic silencing of neuronal gene expressionInteraction of Bunyamwera Orthobunyavirus NSs protein with mediator protein MED8: a mechanism for inhibiting the interferon responseMediator-dependent nuclear receptor functionThe potential link between PML NBs and ICP0 in regulating lytic and latent infection of HSV-1Structure and VP16 binding of the Mediator Med25 activator interaction domainStructure of the VP16 transactivator target in the MediatorSolution NMR structure of MED25(391–543) comprising the activator-interacting domain (ACID) of human mediator subunit 25The Acidic Transcription Activator Gcn4 Binds the Mediator Subunit Gal11/Med15 Using a Simple Protein Interface Forming a Fuzzy ComplexMechanism of Mediator recruitment by tandem Gcn4 activation domains and three Gal11 activator-binding domainsThe Mediator complex and transcription regulationThe mammalian Mediator complexInteraction studies of the human and Arabidopsis thaliana Med25-ACID proteins with the herpes simplex virus VP16- and plant-specific Dreb2a transcription factorsCharacterization of ERM transactivation domain binding to the ACID/PTOV domain of the Mediator subunit MED25Complexity in transcription control at the activation domain-mediator interface.A sequence-specific transcription activator motif and powerful synthetic variants that bind Mediator using a fuzzy protein interface.Two modes of transcriptional activation at native promoters by NF-kappaB p65Herpes simplex virus VP16, but not ICP0, is required to reduce histone occupancy and enhance histone acetylation on viral genomes in U2OS osteosarcoma cells.Inhibition of SREBP transcriptional activity by a boron-containing compound improves lipid homeostasis in diet-induced obesityMediator and human diseaseGenome-Scale CRISPR-Mediated Control of Gene Repression and ActivationMed25 is required for RNA polymerase II recruitment to specific promoters, thus regulating xenobiotic and lipid metabolism in human liver.Function and regulation of the Mediator complex.A systematic analysis of host factors reveals a Med23-interferon-λ regulatory axis against herpes simplex virus type 1 replication.The Arabidopsis thaliana Med25 mediator subunit integrates environmental cues to control plant development.Promoter activation by the varicella-zoster virus major transactivator IE62 and the cellular transcription factor USF.Quantitative proteomic analysis of distinct mammalian Mediator complexes using normalized spectral abundance factors.Phosphorylation of the VP16 transcriptional activator protein during herpes simplex virus infection and mutational analysis of putative phosphorylation sites.Identification of a common epitope between enterovirus 71 and human MED25 proteins which may explain virus-associated neurological disease.Proteomic analysis of the herpes simplex virus 1 virion protein 16 transactivator protein in infected cellsBarrier-to-Autointegration Factor 1 (BAF/BANF1) Promotes Association of the SETD1A Histone Methyltransferase with Herpes Simplex Virus Immediate-Early Gene Promoters.Reactivation of MASPIN in non-small cell lung carcinoma (NSCLC) cells by artificial transcription factors (ATFs)Mediator subunits MED1 and MED24 cooperatively contribute to pubertal mammary gland development and growth of breast carcinoma cells.An activation domain within the walleye dermal sarcoma virus retroviral cyclin protein is essential for inhibition of the viral promoter.Endoplasmic reticulum stress-responsive transcription factor ATF6α directs recruitment of the Mediator of RNA polymerase II transcription and multiple histone acetyltransferase complexes.Comparative genomics supports a deep evolutionary origin for the large, four-module transcriptional mediator complexVaricella-zoster virus IE62 protein utilizes the human mediator complex in promoter activation.The dynamics of HCF-1 modulation of herpes simplex virus chromatin during initiation of infection.
P2860
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P2860
A novel docking site on Mediator is critical for activation by VP16 in mammalian cells
description
2003 nî lūn-bûn
@nan
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
A novel docking site on Mediator is critical for activation by VP16 in mammalian cells
@ast
A novel docking site on Mediator is critical for activation by VP16 in mammalian cells
@en
A novel docking site on Mediator is critical for activation by VP16 in mammalian cells
@nl
type
label
A novel docking site on Mediator is critical for activation by VP16 in mammalian cells
@ast
A novel docking site on Mediator is critical for activation by VP16 in mammalian cells
@en
A novel docking site on Mediator is critical for activation by VP16 in mammalian cells
@nl
prefLabel
A novel docking site on Mediator is critical for activation by VP16 in mammalian cells
@ast
A novel docking site on Mediator is critical for activation by VP16 in mammalian cells
@en
A novel docking site on Mediator is critical for activation by VP16 in mammalian cells
@nl
P2093
P2860
P3181
P356
P1433
P1476
A novel docking site on Mediator is critical for activation by VP16 in mammalian cells
@en
P2093
F Lottspeich
Gerhard Mittler
Lisa Santolin
Lucia Berti
Michael Meisterernst
Thomas Stühler
Thomas Uhlmann
P2860
P304
P3181
P356
10.1093/EMBOJ/CDG619
P407
P577
2003-12-15T00:00:00Z