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Ubiquitination regulates PTEN nuclear import and tumor suppressionRegulation of Rap2A by the ubiquitin ligase Nedd4-1 controls neurite developmentLoss of Mel-18 induces tumor angiogenesis through enhancing the activity and expression of HIF-1α mediated by the PTEN/PI3K/Akt pathwayRak functions as a tumor suppressor by regulating PTEN protein stability and functionX-linked inhibitor of apoptosis protein (XIAP) regulates PTEN ubiquitination, content, and compartmentalizationHuman BRE1 is an E3 ubiquitin ligase for Ebp1 tumor suppressorCSIG inhibits PTEN translation in replicative senescenceNovel control of S phase of the cell cycle by ubiquitin-conjugating enzyme H7Purinergic receptor-mediated rapid depletion of nuclear phosphorylated Akt depends on pleckstrin homology domain leucine-rich repeat phosphatase, calcineurin, protein phosphatase 2A, and PTEN phosphatasesSCF(β-TRCP)-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathwayProtein kinases and phosphatases in the control of cell fateNedd4 augments the adaptive immune response by promoting ubiquitin-mediated degradation of Cbl-b in activated T cellsEmerging role of Lys-63 ubiquitination in protein kinase and phosphatase activation and cancer developmentRegulation of PTEN/Akt and MAP kinase signaling pathways by the ubiquitin ligase activators Ndfip1 and Ndfip2E3 ligase Nedd4 promotes axon branching by downregulating PTENTherapeutic Implications of Targeting AKT Signaling in MelanomaUbiquitin-dependent regulation of phospho-AKT dynamics by the ubiquitin E3 ligase, NEDD4-1, in the insulin-like growth factor-1 responseNedd4 controls animal growth by regulating IGF-1 signalingThe ubiquitin ligase Nedd4-1 is dispensable for the regulation of PTEN stability and localizationNedd4 and Nedd4-2: closely related ubiquitin-protein ligases with distinct physiological functionsThe PTEN tumor suppressor gene and its role in lymphoma pathogenesisPhosphatase and Tensin Homologue: Novel Regulation by Developmental SignalingFocus on PTEN RegulationTargeting the ubiquitin pathway for cancer treatmentPTEN modulators: a patent reviewPTEN plasticity: how the taming of a lethal gene can go too farUbiquitination and phosphorylation of Beclin 1 and its binding partners: Tuning class III phosphatidylinositol 3-kinase activity and tumor suppressionPTEN regulation of ERK1/2 signaling in cancerPhosphoinositides: tiny lipids with giant impact on cell regulationNEDD4: a promising target for cancer therapyTargeting the ubiquitin-proteasome system in heart disease: the basis for new therapeutic strategiesBreast tumor cells with PI3K mutation or HER2 amplification are selectively addicted to Akt signalingTherapeutic targeting of cancers with loss of PTEN function.Deubiquitylase OTUD3 regulates PTEN stability and suppresses tumorigenesisNedd4 E3 ubiquitin ligase promotes cell proliferation and autophagyPTEN is a protein tyrosine phosphatase for IRS1Transforming growth factor-beta regulates DNA binding activity of transcription factor Fli1 by p300/CREB-binding protein-associated factor-dependent acetylationThe intrinsically disordered tails of PTEN and PTEN-L have distinct roles in regulating substrate specificity and membrane activityA phosphorylation-dependent intramolecular interaction regulates the membrane association and activity of the tumor suppressor PTEN.NO signaling and S-nitrosylation regulate PTEN inhibition in neurodegeneration
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN
@ast
NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN
@en
NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN
@en-gb
NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN
@nl
type
label
NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN
@ast
NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN
@en
NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN
@en-gb
NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN
@nl
prefLabel
NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN
@ast
NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN
@en
NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN
@en-gb
NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN
@nl
P2093
P2860
P50
P3181
P1433
P1476
NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN
@en
P2093
Andrea Alimonti
Junru Wang
Lloyd C Trotman
Theresa Koppie
Xinjiang Wang
Xuejun Jiang
Zhenbang Chen
Zhonghua Gao
P2860
P304
P3181
P356
10.1016/J.CELL.2006.11.039
P407
P577
2007-01-12T00:00:00Z