Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis - Test2 - elhamkhani - TriplyDB

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

http://www.wikidata.org/entity/Q24681977

about

Attenuation of PTEN increases p21 stability and cytosolic localization in kidney cancer cells: a potential mechanism of apoptosis resistance."Sentinel" circulating tumor cells allow early diagnosis of lung cancer in patients with chronic obstructive pulmonary disease Mitochondrial dysfunction in Pten haplo-insufficient mice with social deficits and repetitive behavior: interplay between Pten and p53 NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN Ubiquitination regulates PTEN nuclear import and tumor suppression Physical and functional interaction between PML and TBX2 in the establishment of cellular senescence Nek4 regulates entry into replicative senescence and the response to DNA damage in human fibroblasts Cancer-associated PTEN mutants act in a dominant-negative manner to suppress PTEN protein function Dynamic regulation of p53 subnuclear localization and senescence by MORC3 Wig1 prevents cellular senescence by regulating p21 mRNA decay through control of RISC recruitment Reciprocal regulation of p53 and malic enzymes modulates metabolism and senescence Loss of Nkx3.1 leads to the activation of discrete downstream target genes during prostate tumorigenesis Regulation of ploidy and senescence by the AMPK-related kinase NUAK1 Autophagy mediates the mitotic senescence transition The M-type receptor PLA2R regulates senescence through the p53 pathway Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent manner Cellular senescence controls fibrosis in wound healing α-catenin is a tumor suppressor that controls cell accumulation by regulating the localization and activity of the transcriptional coactivator Yap1 Androgen depletion induces senescence in prostate cancer cells through down-regulation of Skp2 The miR-17-92 cluster of microRNAs confers tumorigenicity by inhibiting oncogene-induced senescence Senescence of activated stellate cells limits liver fibrosis Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence Switching Akt: from survival signaling to deadly response The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing Remodeling of chromatin structure in senescent cells and its potential impact on tumor suppression and aging p38alpha and p38gamma mediate oncogenic ras-induced senescence through differential mechanisms The HBP1 transcriptional repressor participates in RAS-induced premature senescence Molecular dissection of formation of senescence-associated heterochromatin foci BRCA1: cell cycle checkpoint, genetic instability, DNA damage response and cancer evolution Advances in genetics: widening our understanding of prostate cancer Therapeutic Targeting of Telomerase Retinoblastoma tumor suppressor functions shared by stem cell and cancer cell strategies Noncoding RNA control of cellular senescence DNA damage response and prostate cancer: defects, regulation and therapeutic implications PTEN modulators: a patent review PTEN plasticity: how the taming of a lethal gene can go too far Methodological aspects of the molecular and histological study of prostate cancer: focus on PTEN Turning off AKT: PHLPP as a drug target Translating insights of AR signaling from mouse models The role of phosphoinositide-regulated actin reorganization in chemotaxis and cell migration

P2860

Q21093282-BD6ABC8E-DD90-43DA-9EB4-136D31B74665 Q21131903-59F6536D-E49D-4A80-BE55-8E684505FD9C Q21560776-7D84C58A-BE98-4D48-8300-4A77D5EF9982 Q24292919-80B5B699-15D0-4EEF-925E-FE060F5037D9 Q24292946-2E3D414A-043A-4CB0-9814-41E668FFD777 Q24293467-BC2A5AE7-A028-4622-A74C-5507780EE95A Q24294537-7D1270EA-3300-48EB-BABE-D574B4FC5969 Q24295164-2783C3DF-D19A-4F7F-A848-986C7A4BE502 Q24298683-86876C4D-09A5-4576-A7E3-C1E16BAAC543 Q24301358-66F7463C-255D-4214-8E92-5325F6A5E5CF Q24310386-503BABE3-B405-4E61-9FE4-519BBC3EEE6C Q24314483-071D8AC4-EAD1-446F-A791-60048648A6CB Q24318723-81432111-0409-4B75-96BE-B8D6F156E9E3 Q24320401-329A8663-A689-4B20-AD4A-F7C080D65E2C Q24336758-66B610E8-E531-4595-BE5A-21D275340F6C Q24337323-5DD76629-A473-4E6A-98D2-D83030826769 Q24602488-549E0F96-294D-48B9-904C-2136F03C0BAF Q24613385-6BADD9B2-BBA8-4261-9966-103E5B877CC2 Q24614665-C0AA8DE0-19F7-4FB0-BD83-6C4033F472EA Q24617045-51F8101D-398B-426F-8159-DEAA58753D07 Q24621822-C465B480-7002-441F-8B6D-02702C33FD49 Q24627126-097682C5-F344-492A-8B8C-B20299F78492 Q24632379-D5723BE1-F64E-4BF2-8250-13BFDF3C6D9F Q24633454-CC70AC66-60B6-4241-AC6D-0DB27641B8E4 Q24642706-38A79C68-8FA5-41FC-B1AA-774B82F942F3 Q24657888-D0B3BEC0-66EB-4DD0-8A28-E6C3AEDD0C85 Q24672298-D182A20D-D160-4AFF-B84F-AB4B0621EE68 Q24681416-D54807BA-E1F8-43FA-A19D-19E8DAC7C3B8 Q25255829-1AF01470-A685-41C7-8E89-819D1489F5CC Q26740628-3D8FB1BE-8F67-49EE-967A-FF4227879570 Q26741736-7575B64B-E767-4F06-A75D-205DB7B2C0AB Q26750380-53817BD9-0163-4288-9E93-D25475EF3DCE Q26786557-A91649A3-67CC-4FD4-B969-306FDE32F5AF Q26829155-21658F01-D9BE-4DCD-8060-868AEB597123 Q26995513-E60F7A9C-F5B5-4144-A3A3-DCB5FAAD325F Q26995683-8BF18F13-20D4-42EE-81F5-8E606E769AA3 Q27005677-2333E4C0-98C8-489D-B285-A16DAFDC1260 Q27014094-D93B862C-0485-45C4-BBB1-80B1C49746BE Q27014822-DF909C47-E352-4117-ABD9-490D9B1068BA Q27021287-56DBAA7D-D43C-4AD7-8518-570D1DEE8E61

P2860

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

http://www.wikidata.org/entity/Q24681977

description

2005 nî lūn-bûn

@nan

2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2005年の論文

@ja

2005年学术文章

@wuu

2005年学术文章

@zh-cn

2005年学术文章

@zh-hans

2005年学术文章

@zh-my

2005年学术文章

@zh-sg

2005年學術文章

@yue

name

Crucial role of p53-dependent ...... f Pten-deficient tumorigenesis

@ast

Crucial role of p53-dependent ...... f Pten-deficient tumorigenesis

@en

Crucial role of p53-dependent ...... f Pten-deficient tumorigenesis

@nl

type

label

Crucial role of p53-dependent ...... f Pten-deficient tumorigenesis

@ast

Crucial role of p53-dependent ...... f Pten-deficient tumorigenesis

@en

Crucial role of p53-dependent ...... f Pten-deficient tumorigenesis

@nl

prefLabel

Crucial role of p53-dependent ...... f Pten-deficient tumorigenesis

@ast

Crucial role of p53-dependent ...... f Pten-deficient tumorigenesis

@en

Crucial role of p53-dependent ...... f Pten-deficient tumorigenesis

@nl

P1433

Q24681977-B6F8461F-79F6-4B6D-B0D0-BDDEBD330C53

P1476

Q24681977-C235F7AA-10A1-4EED-A1EC-87CDE7486F52

P2093

Q24681977-0D7B9826-11CD-4866-B78C-9186219C4E37

Q24681977-2AF47F49-8FEA-43DD-A071-085D60E83811

Q24681977-37634E13-5C2D-423F-AD1C-5CF24D7D05A8

Q24681977-48973E0E-AF01-465D-8599-383ABA8897BB

Q24681977-6764646E-9509-4349-A79B-B7201BA32F29

Q24681977-6C68000C-B7EE-498D-B2D1-77BFD7AFDD76

Q24681977-7A794479-BA59-4688-BF96-DD1CEF3BC3E7

Q24681977-B046E256-A401-45A1-9C43-CAA446515CD9

Q24681977-D0F26EFE-B369-4805-A81F-27A95AA99749

Q24681977-EAD95478-CD31-4C99-9284-B83549133E59

P2860

Q24681977-05F29203-00F2-4336-9812-AD2715D15FEC

Q24681977-08A73DAC-8985-4060-B301-B4E3C661C889

Q24681977-16C537BF-554D-483F-91C9-B760C1B4E3E6

Q24681977-1D5E8CF0-7C55-41E1-9E70-6BC243003E74

Q24681977-2C44E713-0E0B-4484-B133-5D0EDAB51CED

Q24681977-2D171F0C-6FBD-4FCC-B596-43DC078D9FF9

Q24681977-373D1EED-84BF-4AE7-BD1D-4ACE12721705

Q24681977-4AFA0BA7-9AE2-475E-9900-14B761BF6637

Q24681977-57B9CABB-371E-46ED-9CAA-6E32D5086028

Q24681977-6BFAA43E-3A66-41F3-B2BE-624C6C726965

P2888

Q24681977-FE5ECD3A-5C13-4822-8ECF-2396917E9847

P304

Q24681977-27DCCEF9-FB86-4166-A367-207B522FA945

P31

Q24681977-0B002570-E3D4-429C-B7F2-673F4CC41E74

P3181

Q24681977-3A513C55-F67B-4C03-821B-CE2935EF702A

P356

Q24681977-983D6417-1CE1-4342-971C-C17A0885B6B2

P407

Q24681977-53EB33A9-BF80-427E-91F8-685BF6DC29F9

P433

Q24681977-56CF2635-9A5C-4693-97E6-18376B0330C9

P478

Q24681977-5CBC3589-1AB7-4D6B-A132-46EB4A195389

P50

Q24681977-45E14353-9624-40FA-B62C-FF9B42DBBEC2

Q24681977-58000B11-DAAC-43F8-BDEB-EED391C673FF

P577

Q24681977-4EF17D37-6832-4FC5-A0E5-0FA82CCC0FC8

P5875

Q24681977-C4527D9B-2CC0-4DEF-B85C-C6293E14DAD1

P6179

Q24681977-AB3A3367-E0BD-4BA1-B044-4527DE6A6BDD

P698

Q24681977-B1A44186-A895-4AE8-831F-67854B639476

P932

Q24681977-D120D65C-2FDC-40F5-87CD-AD020B0C25B8

P3181

P356

P1433

P1476

Crucial role of p53-dependent ...... f Pten-deficient tumorigenesis

@en

P2093

David Shaffer

http://www.w3.org/2001/XMLSchema#string

Howard I Scher

http://www.w3.org/2001/XMLSchema#string

Hui-Kuan Lin

http://www.w3.org/2001/XMLSchema#string

Jason A Koutcher

http://www.w3.org/2001/XMLSchema#string

Lloyd C Trotman

http://www.w3.org/2001/XMLSchema#string

Masaru Niki

http://www.w3.org/2001/XMLSchema#string

Thomas Ludwig

http://www.w3.org/2001/XMLSchema#string

William Gerald

http://www.w3.org/2001/XMLSchema#string

Zhenbang Chen

http://www.w3.org/2001/XMLSchema#string

Zohar A Dotan

http://www.w3.org/2001/XMLSchema#string

P2860

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

Pten dose dictates cancer progression in the prostate

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

Surfing the p53 network

PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms

Role of the proto-oncogene Pokemon in cellular transformation and ARF repression

Regulation of PTEN transcription by p53

Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound.

Generation of a prostate epithelial cell-specific Cre transgenic mouse model for tissue-specific gene ablation.

The multiple roles of PTEN in tumor suppression.

P2888

P304

725-30

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

968449

http://www.w3.org/2001/XMLSchema#string

P356

10.1038/NATURE03918

http://www.w3.org/2001/XMLSchema#string

P407

P433

7051

http://www.w3.org/2001/XMLSchema#string

P478

436

http://www.w3.org/2001/XMLSchema#string

P50

Carlos Cordon-Cardo

Pier Paolo Pandolfi

P577

2005-08-04T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

7679856

http://www.w3.org/2001/XMLSchema#string

P6179

1027424701

http://www.w3.org/2001/XMLSchema#string

P698

16079851

http://www.w3.org/2001/XMLSchema#string

P932

1939938

http://www.w3.org/2001/XMLSchema#string