The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome
about
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)TRIM proteins regulate autophagy and can target autophagic substrates by direct recognitionHistone deacetylase 6 plays a role as a distinct regulator of diverse cellular processesRole of Cigarette Smoke-Induced Aggresome Formation in Chronic Obstructive Pulmonary Disease-Emphysema PathogenesisAggresome formation is regulated by RanBPM through an interaction with HDAC6RNA-seq analysis of broiler liver transcriptome reveals novel responses to high ambient temperature.SQSTM1/p62 interacts with HDAC6 and regulates deacetylase activity.Overexpression of the transcriptional repressor complex BCL-6/BCoR leads to nuclear aggregates distinct from classical aggresomesTRIM32-Cytoplasmic-Body Formation Is an ATP-Consuming Process Stimulated by HSP70 in Cells.HDAC6 and ovarian cancer.The HDAC inhibitor AR42 interacts with pazopanib to kill trametinib/dabrafenib-resistant melanoma cells in vitro and in vivo.Inclusion body formation, macroautophagy, and the role of HDAC6 in neurodegeneration.Regulation of autophagy by protein post-translational modification.Autophagy in neuronal cells: general principles and physiological and pathological functions.Enhanced proteotoxic stress: one of the contributors for hyperthermic potentiation of the proteasome inhibitor bortezomib using magnetic nanoparticles.Targeting the integrated networks of aggresome formation, proteasome, and autophagy potentiates ER stress‑mediated cell death in multiple myeloma cells.Multilevel regulation of autophagosome content by ethanol oxidation in HepG2 cells.The HECT E3 ubiquitin ligase NEDD4 interacts with and ubiquitylates SQSTM1 for inclusion body autophagy.Class II HDACs and neuronal regeneration.Interplay Between the Autophagy-Lysosomal Pathway and the Ubiquitin-Proteasome System: A Target for Therapeutic Development in Alzheimer's Disease.TRIM50 suppressed hepatocarcinoma progression through directly targeting SNAIL for ubiquitous degradation.
P2860
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P2860
The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome
description
2012 nî lūn-bûn
@nan
2012 թուականին հրատարակուած գիտական յօդուած
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2012 թվականին հրատարակված գիտական հոդված
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2012年の論文
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2012年論文
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2012年論文
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2012年論文
@zh-hk
2012年論文
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2012年論文
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2012年论文
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name
The E3-ubiquitin ligase TRIM50 ...... ed proteins into the aggresome
@ast
The E3-ubiquitin ligase TRIM50 ...... ed proteins into the aggresome
@en
The E3-ubiquitin ligase TRIM50 ...... ed proteins into the aggresome
@en-gb
The E3-ubiquitin ligase TRIM50 ...... ed proteins into the aggresome
@nl
type
label
The E3-ubiquitin ligase TRIM50 ...... ed proteins into the aggresome
@ast
The E3-ubiquitin ligase TRIM50 ...... ed proteins into the aggresome
@en
The E3-ubiquitin ligase TRIM50 ...... ed proteins into the aggresome
@en-gb
The E3-ubiquitin ligase TRIM50 ...... ed proteins into the aggresome
@nl
prefLabel
The E3-ubiquitin ligase TRIM50 ...... ed proteins into the aggresome
@ast
The E3-ubiquitin ligase TRIM50 ...... ed proteins into the aggresome
@en
The E3-ubiquitin ligase TRIM50 ...... ed proteins into the aggresome
@en-gb
The E3-ubiquitin ligase TRIM50 ...... ed proteins into the aggresome
@nl
P2093
P2860
P50
P921
P1433
P1476
The E3-ubiquitin ligase TRIM50 ...... ed proteins into the aggresome
@en
P2093
Alessia Calcagnì
Alexandre Reymond
Bartolomeo Augello
Ester Valentina D'Addetta
Gerard Didelot
Giuseppe Merla
Mikhail Egorov
Roman S Polishchuk
P2860
P304
P356
10.1371/JOURNAL.PONE.0040440
P407
P577
2012-07-09T00:00:00Z